INTRODUCTION

METASONE S OINTMENT is a combination of Mometasone and Salicylic acid which belongs to the group of medicines called Dermatological agents. METASONE S OINTMENT is used to treat psoriasis, especially in case of intensive scaling, in adults and adolescents (above 12 years of age).

Psoriasis is a type of skin disease that causes a skin rash with itchy, scaly patches, most commonly on the knees, elbows, trunk and scalp which is a common, long-term disease that occurs due to triggering factors such as infections, cuts, burns and/or certain medications which is generally painful and tends to go through cycles, flaring for a few weeks to months.

Avoid applying METASONE S OINTMENT if you have bacterial infection such as pyoderma (pus-producing skin disease), syphilis (sexually transmited bacterial disease), tuberculosis, viral infections such as herpes simplex, chicken pox, fungal infections such as dermatophyte, yeast and rosacea (type of skin disease) marked by reddens and or other changes of the skin in the facial area.

Before applying METASONE S OINTMENT, inform your doctor if you are receiving ultraviolet treatment and have any other skin problems. METASONE S OINTMENT is not recommended for use during pregnancy and breast-feeding women should consult their doctor before use.

METASONE S OINTMENT is recommended for use in children and adolescents (above 12 years of age). The most common side effects of using METASONE S OINTMENT are weak to moderate burning sensation at the site of application, itching and localized thinning of the skin. Consult your doctor if any of the side effect gets worse. 

USES OF METASONE S OINTMENT

• Treats psoriasis, especially in case of intensive scaling

HOW METASONE S OINTMENT WORKS

METASONE S OINTMENT is used to treat psoriasis, where Mometasone reduces the redness and itchiness of skin by blocking the production of prostaglandin (chemical messenger), which is responsible for causing redness and itchiness of skin and Salicylic acid helps in softening and removing the psoriasis scales by acting as a scale filter which causes shedding of outer layer of the skin thereby providing relief from the symptoms of psoriasis.

DIRECTIONS FOR USE

Always apply METASONE S OINTMENT as directed by your physician. It is for external use only. On the affected area, apply a thin layer of this medicine. It should not be applied under bandages or similar. Avoid applying the medicine around your eyes or mucous membrane. Your doctor will decide the duration and frequency of using this medicine depending upon severity of the condition. 

SIDE EFFECTS OF METASONE S OINTMENT

HOW TO MANAGE SIDE EFFECTS

Skin itching:

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Avoid sun exposure or UV rays as it may sensitize your skin. Use sunscreen and protective clothing when going outdoor. Regularly moisturize your skin after consulting the doctor. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions:

Before using METASONE S OINTMENT, inform your doctor if you are using any medicines including prescription or non-prescription medicines.

Overdosage:

If you or anyone else accidentally applied too much of METASONE S OINTMENT, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep METASONE S OINTMENT out of reach of children
• Store METASONE S OINTMENT at room temperature

FAQs ABOUT METASONE S OINTMENT

What is METASONE S OINTMENT used for?

METASONE S OINTMENT is used to treat psoriasis in adults and adolescents (above 12 years of age) which is a type of skin disease that causes a skin rash with itchy, scaly patches, most commonly seen on the knees, elbows, trunk and scalp.

What happens if you suddenly stop METASONE S OINTMENT?

Do not use METASONE S OINTMENT twice to make up for a forgotten dose. Make up for the dose you forgot as soon as possible, and then continue treatment at the regularly scheduled intervals. Consult your doctor before applying METASONE S OINTMENT if you are uncertain about the forgotten dose.

Who should avoid using METASONE S OINTMENT?

METASONE S OINTMENT is not recommended for use in patients allergic to Mometasone and Salicylic acid and/or have bacterial infection such as pyoderma (pus-producing skin disease), syphilis (sexually transmited bacterial disease), tuberculosis, viral infections such as herpes simplex, chicken pox, fungal infections such as dermatophyte, yeast and rosacea (type of skin disease) marked by reddens and or other changes of the skin in the facial area.

Is METASONE S OINTMENT safe to be used in pregnant women?

METASONE S OINTMENT is not recommended for use during the last three months of pregnancy and it should be avoided during the first six months of pregnancy. Consult your doctor before using METASONE S OINTMENT.

How METASONE S OINTMENT should be applied on the site of infection?

Always apply METASONE S OINTMENT as directed by your physician. It is for external use only. On the affected area, apply a thin layer of this medicine. It should not be applied under bandages or similar. Avoid applying the medicine around your eyes or mucous membrane. Your doctor will decide the duration and frequency of using this medicine depending upon severity of the condition.  

REFERENCES

1. KD. Tripathi. Drugs Acting on Skin & Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 889 &  895.

2. Azidus Brasil. Efficacy Study of the Combination Mometasone + Salicylic Acid in Patients With Psoriasis (Psoriasis). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in October 2010] [Accessed on 23rd May 2022] https://clinicaltrials.gov/ct2/show/NCT01229085

3. Fabrizio Spada, Tanya M Barnes and Kerryn A Greive. Comparative safety and efficacy of topical mometasone furoate with other topical corticosteroids. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. February 2018. [Accessed on 23rd May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099284/

4. Luís Uva, Diana Miguel, Catarina Pinheiro, Joana Antunes, Diogo Cruz, Joao Ferreira, and Paulo Filipe. Mechanisms of Action of Topical Corticosteroids in Psoriasis. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. November 2012 [Accessed on 23rd May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508578/

5. Salicylic Acid Topical. Medline Plus. NIH National Library of Medicine. September 2016 [Accessed on 23rd May 2022] https://medlineplus.gov/druginfo/meds/a607072.html

6. Mometasone furoate. Dailymed. NIH National Library of Medicine. November 2020 [Accessed on 23rd May 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=ce3b155b-2e84-86cc-91db-0c86bc805ab6

7. Schering-Plough Labo nv. Medical Products Agency (MPA). [Revised in June 2018] [Accessed on 23rd May 2022] https://docetp.mpa.se/LMF/Elosalic%20ointment%20ENG%20PL_09001be680179b9e.pdf

USEFUL DIAGNOSTIC TESTS

• Skin biopsy test