INTRODUCTION

MERCIDINE OZ is a combination of Ornidazole and Povidone Iodine which belongs to the group of medicines called Nitroimidazoles and Antiseptics respectively. It is used to prevent, control, treat and improve condition and symptoms of wound infection, minor cuts, graze, burns, boils, ulcers, blisters, abrasion, bacterial infections (such as paronychia, impetigo, furunculosis, otitis externa, sycosis barbae), fungal infections (such as tinea infestation, custodian candidiasis), protozoan infections, and infections that occurs after surgical procedures.

MERCIDINE OZ is not recommended for use if you have any health condition or illness. Before using MERCIDINE OZ, inform your doctor if you are planned for any upcoming surgery, have fits, or multiple sclerosis (an autoimmune disease). MERCIDINE OZ is not recommended for use in pregnant and breast-feeding women.

Also, it is not recommended for use in children (aged below 2 years) and neonates, and it should be used with caution in elderly patients (aged above 70 years). The most common side effects of using MERCIDINE OZ are local irritation, rashes, burning or stinging sensation and redness. Consult your doctor if any of the side effect worsens.

USES OF MERCIDINE OZ

Used to prevent, control, treat and improve condition and symptoms of:

• wound infection, minor cuts and graze, burns, boils, ulcers, blisters, abrasion
• bacterial infections (such as paronychia, impetigo, furunculosis, otitis externa, sycosis barbae)
• fungal infections (such as tinea infestation, custodian candidiasis)
• protozoan infections
• infections that occurs after surgical procedures

HOW MERCIDINE OZ WORKS

MERCIDINE OZ is a combination of Ornidazole and Povidone iodine, where ornidazole works by damaging the DNA of the microorganism on the infected site which results in destruction of the bacteria and other infectious microorganisms. Povidone iodine works by releasing iodine on the infected site which causes destruction and prevention of growth of infectious microorganisms on the infected site thereby treating the infection.

DIRECTIONS FOR USE

Apply MERCIDINE OZ as directed by your physician. It is for external use only. Clean and dry the affected area before the application. Wash your hands before and after applying MERCIDINE OZ. Avoid applying this medicine around your eyes, including eyelids. Your doctor will decide the duration of treatment depending upon the severity of the infection or wound.

SIDE EFFECTS OF MERCIDINE OZ

HOW TO MANAGE SIDE EFFECTS

Rashes:

Avoid taking shower or bath in hot water as it worsen the condition and pat dry the skin. Do not scratch the affected area. Wear protective clothing while going outdoors. Regularly moisturize your skin after consulting the doctor. Consult your doctor if the symptom gets worse.  

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug – Drug Interaction:

Before using MERCIDINE OZ, inform your doctor if you are using any medicines including prescription, non-prescription and herbal or vitamin supplements.

Overdosage:

In case of overdosage or accidental ingestion of MERCIDINE OZ, consult your doctor or visit the nearby hospital immediately.

SYNOPSIS

MORE INFORMATION

• Keep MERCIDINE OZ out of reach of children
• Store at room temperature

FAQs ABOUT MERCIDINE OZ

What is MERCIDINE OZ and why is it given?

MERCIDINE OZ contains Ornidazole and Povidone Iodine which belongs to the group of medicines called Nitroimidazoles and Antiseptics. It is used to prevent, control, treat and improve condition and symptoms of wound infection, minor cuts, burns, boils, ulcers, blisters, abrasion and certain bacterial, fungal and protozoan infections, also used treat infections that occurs after surgical procedures.

What are the common side effects of MERCIDINE OZ?

The most common side effects associated with the use of MERCIDINE OZ are local irritation, rashes, burning sensation, stinging and redness. Consult your doctor if any of the side effect worsens or bothers you.

Who should avoid applying MERCIDINE OZ?

MERCIDINE OZ is not recommended for use in patients who are allergic to ornidazole and povidone iodine and it is not recommended for use in pregnant and breastfeeding women. Consult your doctor before using MERCIDINE OZ.

Can MERCIDINE OZ be used in children?

MERCIDINE OZ is not recommended for use in children (below 2 years of age) and in neonates. If MERCIDINE OZ is accidentally ingested by a child or adolescent, go to the hospital immediately and consult the doctor for further management.

How MERCIDINE OZ should be applied?

Apply MERCIDINE OZ as directed by your physician. It is for external use only. Clean and dry the affected area before the application. Wash your hands before and after applying MERCIDINE OZ. Avoid applying this medicine around your eyes, including eyelids. Your doctor will decide the duration of treatment depending upon the severity of the infection or wound.

REFERENCES

1. Laurence L. Brunton, John S. Lazo, Keith L. Parker. Ophthalmology. Goodman & Gilman's The Pharmacological Basis of Therapeutics. Eleventh Edition. 2005. Page – 1734.

2. KD. Tripathi. Antiamoebic and Antiprotozoal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 839.

3. Yehouda Marcus, Noam Tal, Mordechai Ronen, Raanan Carmieli, Michael Gurevitz. The drug ornidazole inhibits photosynthesis in a different mechanism described for protozoa and anaerobic bacteria. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. December 2016. [Accessed on 11th June 2022] https://pubmed.ncbi.nlm.nih.gov/27647935/#:~:text=Abstract,of%20toxic%20derivatives%20and%20radicals

4. Subuhi Kaul, Savita Yadav, and Sunil Dogra. Treatment of Dermatophytosis in Elderly, Children, and Pregnant Women. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. September 2017. [Accessed on 11th June 2022] https://pubmed.ncbi.nlm.nih.gov/27647935/#:~:text=Abstract,of%20toxic%20derivatives%20and%20radicals

5. DM Pharma. Batodine Plus (Povidone Iodine and Ornidazole ointment). [Accessed on 11th June 2022] https://www.dmpharma.co.in/Povidone%20%E2%80%93%20Iodine%20+%20Ornidazole%20Ointment.html

6. Wellona Pharma. Wellodin-OR (Povidone Iodine and Ornidazole) [Accessed on 11th June 2022] https://wellonapharma.com/product/finished/povidone-iodine-and-ornidazole-cream

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count