INTRODUCTION

MAZZ 200 contain Azithromycin which belongs to a group of medicine called macrolide antibiotics. It is used to treat infections caused by micro-organisms such as bacteria including chest, throat or nasal infection, ear infections, skin and soft tissue infections, sexually transmitted diseases and infection of the tube that carries urine from the bladder (urethra) or the neck of the womb (cervix).

MAZZ 200 is a broad-spectrum type of antibiotic. It is effective in killing many types of gram-positive bacteria, some types of gram-negative bacteria and other microorganisms. This medicine is not suitable for use in children under the age of one year. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF MAZZ 200

Treat bacterial infections such as

• chest, throat, or nasal infections (such as bronchitis, pneumonia, tonsillitis, sore throat, and sinusitis)
• ear infections
• skin and soft tissue infections (such as abscess or boil)
• sexually transmitted diseases caused by Chlamydia trachomatis and Neisseria gonorrhoea
• urethra and cervix infections caused by chlamydia

HOW MAZZ 200 WORKS

MAZZ 200 inhibits the synthesis of essential protein required by bacteria to grow and multiply and thus prevents the infection from spreading.

DIRECTIONS FOR USE

Always take MAZZ 200 exactly as your doctor has told you. Shake well before use.

SIDE EFFECTS OF MAZZ 200

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. Eat and drink slowly and smaller and frequent meals. Applying a heat pad or covered hot water bottle on your stomach may also help. If still pain persists, speak to your doctor.

Nausea and Vomiting:

Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking,

• ergot derivatives such as ergot or ergotamine (used to treat migraine)
• warfarin (used to prevent blood clots)
• ciclosporin (used to suppress the immune system)
• antacids (used to treat heartburn and indigestion)
• digoxin (used to treat heart failure)
• colchicine (used to treat gout and familial mediterranean fever)
• terfenadine, astemizol (used to treat hay fever or a skin allergy)
• cabergoline and pergolide (used to treat parkinson’s disease)
• medicines to treat irregular heartbeat
• cisapride (used to treat gastric reflux disease and constipation)
• antipsychotics such as pimozide (used to treat psychosis problems)
• antidepressants such as citalopram (used to treat depression)
• fluoroquinolones antibiotic such as moxifloxacin and levofloxacin (used to treat infections)
• theophylline (used to treat asthma)
• fluconazole (used to treat fungal infections)
• zidovudine, nelfinavir (used to treat HIV infections)
• alfentanil (used for narcosis)
• statins such as atorvastatin (used for lowering blood cholesterol)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT MAZZ 200

Can I take MAZZ 200 during kidney disease?

It should be used with caution in patients suffering from active kidney diseases.

Can I take MAZZ 200 during heart disease?

It should be used with caution in patients suffering from active heart diseases.

How does MAZZ 200 works?

This medicine inhibits the synthesis of essential protein required by bacteria to grow and multiply and thus prevents the infection from spreading.

REFERENCES

1. Bertram G. Katzung, Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones, Basic & Clinical Pharmacology, Fourteenth Edition, 2015. Page – 820.

2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 360-365.

3. Fabian Yuh Shiong Kong 1, Patrick Horner 2 3, Magnus Unemo 4, Jane S Hocking 1. Pharmacokinetic considerations regarding the treatment of bacterial sexually transmitted infections with azithromycin: a review. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. 1 May 2019. [Accessed 11 Nov 2020] https://pubmed.ncbi.nlm.nih.gov/30649333/

4. Haupt Pharma Latina S.r.l; Electronic Medicines Compendium (EMC); [Revised on May 2018] [Accessed 11 Nov 2020] https://www.medicines.org.uk/emc/files/pil.3006.pdf

5. Haupt Pharma Latina S.r.l; Electronic Medicines Compendium (EMC); [Revised on Apr 2019] [Accessed 11 Nov 2020] https://www.medicines.ie/medicines/zithromax-powder-for-oral-suspension-200-mg-5-ml-34355/patient-info

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count
• Peripheral Smear Examination