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INTRODUCTION
MASOOM SYRUP contains Paracetamol which belongs to the group of medicines called Analgesics and Antipyretics. It is used to relieve mild to moderate pain like headache, migraine, nerve pain, toothache, sore throat, period pains, teething, immunisation, earache, and general aches and pains. It can also be used to treat fever (high temperature), and symptoms of cold or flu.
Before taking MASOOM SYRUP, inform your doctor if you have liver or kidney problems, fructose intolerance, Gilberts syndrome, glucose-6-phosphate dehydrogenase deficiency, hemolytic anaemia, reduced glutathione levels, malnourishment, dehydration or if you weigh less than 50 kg.
MASOOM SYRUP should be used in pregnant women only if considered necessary. Avoid consumption of alcohol during treatment with MASOOM SYRUP, as it might make you more prone to side effects.
MASOOM SYRUP is not recommended for use in children (2-3 months old, weighing less than 4 kg or born before 37 weeks). Contact your doctor if you get any side effects of any of the symptoms get worse.
USES OF MASOOM SYRUP
- Relieves mild to moderate pain, fever, and symptoms of cold or flu
HOW MASOOM SYRUP WORKS
MASOOM SYRUP relieves pain by increasing the pain threshold by inhibiting certain enzymes (COX-1 and COX-2) involved in synthesis of chemicals responsible for inducing pain (prostaglandins). It reduces fever by directly acting on heat-regulating centers in the brain, resulting in vessel relaxation, sweating, and loss of body heat.
DIRECTIONS FOR USE
Take MASOOM SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you based upon your age, body weight and disease condition.
SIDE EFFECTS OF MASOOM SYRUP
COMMON
- skin rash
- blood not clotting well (easy bruising or bleeding)
- nausea, vomiting, constipation
- itching, agitation
RARE
- a severe drop in the number of white blood cells (you become more prone to infections)
- shortness of breath
Stop taking MASOOM SYRUP and contact your doctor immediately if you experience any of the following side effects:
- allergic reaction (skin rash, flaking skin, boils, sore lips and mouth, swollen face, fever, sudden wheezing, fluttering or chest tightness)
- signs of blood disorder (easy bruising, sore throat or other signs of infection)
- pancreas inflammation (severe pain in the abdomen and back, with fever, loss of appetite, nausea, vomiting)
- serious skin reactions (skin reddening, blisters, rash)
- liver and kidney problems (on long-term use)
HOW TO MANAGE SIDE EFFECTS
Constipation
Eat plenty of fiber rich foods like fresh fruits, vegetables, cereals, and drink plenty of water. Exercise more regularly. If you still feel constipated, contact your doctor.
Nausea And Vomiting
Take MASOOM SYRUP with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If you still feel nauseous and vomiting, contact your doctor.
Skin Rash Or Itching
Avoid hot showers because hot water can irritate your skin more. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash gets worse.
WARNING & PRECAUTIONS
PREGNANCY
MASOOM SYRUP should be used in pregnant women only if considered necessary. Consult your doctor before taking it.
BREASTFEEDING
MASOOM SYRUP should be used in breastfeeding women only if considered necessary. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Consult your doctor if you feel any side effect during treatment with MASOOM SYRUP that may stop you from driving or using machines.
ALCOHOL
Avoid consumption of alcohol while taking MASOOM SYRUP. Before taking MASOOM SYRUP, inform your doctor if you have chronic alcoholism.
KIDNEY
MASOOM SYRUP should be used with caution in patients with severe kidney problems. Consult your doctor before taking it.
LIVER
MASOOM SYRUP should be used with caution in patients with severe liver problems, liver problems due to excessive alcohol intake, or have Gilberts syndrome (liver doesn't process bilirubin properly). Consult your doctor before taking it.
ALLERGY
Do not take MASOOM SYRUP if you are allergic to Paracetamol or any of the other ingredients of this medicine.
OTHERS
Before taking MASOOM SYRUP, inform your doctor if you:
- have fructose intolerance or any other type of sugar intolerance
- have sepsis (circulation of bacteria and their toxins in the blood leading to organ damage)
- are malnourished
- are glucose-6-phosphate dehydrogenase deficient (enzyme deficiency)
- have haemolytic anaemia (decreased red blood cells which can make the skin pale yellow and cause weakness or breathlessness)
- have reduced glutathione levels
- are dehydrated or weigh less than 50 kg
Use in pediatrics:
MASOOM SYRUP is not recommended for use in children (2-3 months old, weighing less than 4 kg or born before 37 weeks). Consult your doctor before taking it.
Use in geriatrics:
MASOOM SYRUP should be used with caution in elderly patients. Consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug interactions:
Before taking MASOOM SYRUP, inform your doctor if you are taking any of the following medicines:
- medicines used to induce sleep (Ex. phenobarbital, pentobarbital)
- medicines used in depression (Ex. amitriptyline, nortriptyline)
- cholestyramine (used to control blood fat levels)
- warfarin (used for treating blood clots)
- zidovudine (used to treat HIV infection)
- other medicines containing paracetamol
- medicines to treat nausea and vomiting (Ex. metoclopramide, domperidone)
- medicines used to treat fits (Ex. carbamazepine, phenytoin)
- medicines used to prevent pregnancy (Ex. ethinyl estradiol, norethindrone)
- medicines used to treat bacterial infections (Ex. flucloxacillin, chloramphenicol)
Overdosage:
If you, your child, or anyone else accidentally take too much of MASOOM SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of MASOOM SYRUP overdose are delayed, serious liver damage, paleness, nausea, sweating, vomiting, loss of appetite and stomach pain.
SYNOPSIS
| Drug | : | Paracetamol |
| Pharmacological Category | : | Para aminophenol derivative |
| Therapeutic Indication | : | Pain, Fever |
| Dosage Forms | : | Tablet, Dispersible tablet, Capsule, Drops, Dry syrup, Syrup, Oral suspension, Liquid, Oral solution, Suppositories, Infusion, Injection |
MORE INFORMATION
- Keep MASOOM SYRUP out of reach of children
- Store below 25°C
FAQs ABOUT MASOOM SYRUP
Q: Can MASOOM SYRUP be given to children?
A: MASOOM SYRUP is not recommended for use in children (2-3 months old, weighing less than 4 kg or born before 37 weeks). Your doctor will decide the correct dose or select a suitable alternative treatment for your child.
Q: What if I forget to take a dose of MASOOM SYRUP?
A: If you forget to take a dose of MASOOM SYRUP, take it as soon as you remember. However, omit the missed dose if it's almost time for the next one. Do not take MASOOM SYRUP two times to make up for the missed dose.
Q: Can MASOOM SYRUP prevent pregnancy?
A: No. MASOOM SYRUP does not prevent pregnancy, but it should be used with caution in fertile women. Consult your doctor before taking it.
Q: Can MASOOM SYRUP be stopped?
A: Continue taking MASOOM SYRUP until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. Contact your doctor in such case.
Q: What is MASOOM SYRUP used for?
A: MASOOM SYRUP is used to relieve mild to moderate pain like headache, migraine, nerve pain, toothache, sore throat, period pains, teething, immunisation, earache, and general aches and pains. It can also be used to treat fever (high temperature), and symptoms of cold or flu.
Q: What should I tell my doctor before taking MASOOM SYRUP?
A: Patients taking MASOOM SYRUP must inform their doctor about their pre-existing conditions like kidney or liver problems, or any type of sugar intolerance. Patients should also tell if they are pregnant, breast-feeding, or allergic to anything. Consult your doctor if you experience anything different.
Q: Can MASOOM SYRUP be taken in pregnancy?
A: MASOOM SYRUP should be used in pregnant women only if considered necessary. The lowest possible dose that reduces your pain and/or your fever should be used for the shortest time possible. Contact your doctor if the pain or fever is not relieved or if you need to take the medicine more often. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before taking it.
Q: Can I take other medicines with MASOOM SYRUP?
A: Before taking MASOOM SYRUP, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, over the counter or any herbal medicine, as these might cause serious side effects by interacting with each other.
REFERENCES
1. Tilo Grosser, Emer Smyth and Garret A. FitzGerald. Anti-inflammatory, Antipyretic and Analgesic agents; Pharmacotherapy of gout. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 693.
2. KD. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 206.
3. Freo, U., Ruocco, C., Valerio, A., Scagnol, I., & Nisoli, E. Paracetamol: A Review of Guideline Recommendations. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. August 2021. [Accessed on 13th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8347233/
4. Okereke, B., Ibeleme, O., & Bisi-Onyemaechi, A. Randomised comparative trial of the efficacy of paracetamol syrup and dispersible tablets for the treatment of fever in children. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. March 2021. [Accessed on 13th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985941/
5. Rosemont Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 13th August 2022] https://www.medicines.org.uk/emc/files/pil.6694.pdf
6. Delpharm Orleans. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 13th August 2022] https://www.medicines.org.uk/emc/files/pil.6634.pdf
7. Rosemont Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in July 2021] [Accessed on 13th August 2022] https://www.medicines.org.uk/emc/files/pil.2853.pdf
8. Micro Labs Ltd. Paracetamol. [Accessed on 13th August 2022] https://www.microlabsltd.com/elibrary/node/1782, https://www.microlabsltd.com/elibrary/node/1787, https://www.microlabsltd.com/elibrary/node/1797, https://www.microlabsltd.com/elibrary/node/1800
9. GlaxoSmithKline Asia Private Limited. Paracetamol. [Accessed on 13th August 2022] https://www.crocin.com/products/children-products/5-to-12-years/crocin-suspension-ds.html#
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