INTRODUCTION

MARKTEL 40MG contain Telmisartan which belongs to a group of medicine called angiotensin II receptor antagonists, a substance produced in your body which makes your blood vessels to narrow, thus increasing your blood pressure. This medicine works by blocking the effect of angiotensin II so that the blood vessels relax, and your blood pressure gets lowered. It is also used to decrease the chance of heart attack, stroke, in people who are at high risks for cardiovascular disease.

High blood pressure is a condition where the force of the blood against the artery wall is very high and if it is not treated, can damage blood vessels in several organs. It is important to regularly measure your blood pressure to check whether it is within the normal range.

Heart attack occur when an artery supplying your heart with blood and oxygen become blocked. Fatty deposit over time forms plaques in your heart's arteries which when ruptures forms a blood clot. This blood clot can block your arteries, causing a heart attack. Stroke is a condition where the blood supply to part of your brain is interrupted or reduced which prevents brain tissue from getting oxygen and nutrients. MARKTEL 40MG decrease the chance of heart attack, stroke, in people who are at high risks for cardiovascular disease.

Before taking this medicine, tell your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding mothers should consult their doctor before taking it. The use of MARKTEL 40MG in children and adolescents upto the age of 18 years is not recommended.

USES OF MARKTEL 40MG

• Treat high blood pressure
• Helps to reduce cardiovascular events such as heart attack, stroke

HOW MARKTEL 40MG WORKS

This medicine relaxes the blood vessels by blocking the action of angiotensin II that usually makes your blood vessels narrow. This allows the blood to flow more smoothly to different organs and the heart to pump more efficiently thus lowering the blood pressure.

DIRECTIONS FOR USE

Always take MARKTEL 40MG exactly as your doctor has told you. This medicine must be taken with or without food. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF MARKTEL 40MG

HOW TO MANAGE SIDE EFFECTS

Back pain:

Apply ice and heat. Take bed rest. Keep exercising. Improve flexibility. Take analgesics and anti-inflammatory medicine.

Diarrhoea:

Drink lot of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without consulting to a doctor.

Dizziness:

Lying down and closing the eyes. drink plenty of water and keep hydrated. Take plenty of sleep.

Stomach upset:

Drink water. Avoid lying down. Take warm bath or use a heat bag. Avoid smoking and drinking alcohol. Avoid difficult digest foods.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking,

• lithium containing medicines (used to treat some types of depression)
• potassium, potassium sparing diuretics (used to increase blood potassium levels)
• ACE inhibitors, angiotensin II receptor antagonist (used to treat high blood pressure)
• NSAIDs such as aspirin or ibuprofen and COX-2 inhibitors (used to treat pain and arthritis)
• heparin (used for thinning blood)
• immunosuppressant such as cyclosporin or tacrolimus
• antibiotic such as trimethoprim (used to treat infection)
• diuretics (water tablets)
• medicines with blood pressure lowering potential such as baclofen, amifostine
• alcohol, barbiturates, narcotics, or antidepressants
• digoxin
• ramipril (used to treat high blood pressure or heart problem)

SYNOPSIS

MORE INFORMATION

Store between 15-30°C and keep out of reach of children.

FAQs ABOUT MARKTEL 40MG

How long does it take for MARKTEL 40MG to work?

You may see an improvement within a few days. But the maximum benefit can be seen within 4-8 weeks of starting treatment.

Can the use of MARKTEL 40MG cause hyperkalemia (increased potassium level in blood)?

Yes, it can cause hyperkalemia (increased potassium level in blood). A regular monitoring of blood potassium levels may be advised by your doctor while taking this medicine.

How does MARKTEL 40MG works?

This medicine relaxes the blood vessels by blocking the action of angiotensin II that usually makes your blood vessels narrow. This allows the blood to flow more smoothly to different organs and the heart to pump more efficiently thus lowering the blood pressure.

REFERENCES

1. KD Tripathi. Drugs Affecting Renin-Angiotensin System and Plasma Kinins. Essentials of Medical pharmacology. Seventh edition.2013. Page-507-508.

2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page- 3691-3692.

3. M Sharpe 1, B Jarvis, K L Goa. Telmisartan: a review of its use in hypertension. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov.2001 [Accessed 26 Oct 2020] https://pubmed.ncbi.nlm.nih.gov/11558835/

4. Actavis Ltd; Electronic Medicines Compendium (EMC); [Revised on June 2015] [Accessed 26 Oct 2020] https://www.medicines.org.uk/emc/files/pil.5198.pdf

5. Boehringer Ingelheim Pharmaceuticals, Inc 1998; U.S. Food & Drug Administration; [Revised on May 2011] [Accessed 26 Oct 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020850s032lbl.pdf

USEFUL DIAGNOSTIC TESTS

• Kidney Function Test