MABTHERA 500mg Infusion 50ml

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Drug Information for MABTHERA 500mg Infusion 50ml

What is MABTHERA 500mg Infusion used for?

MABTHERA 500mg Infusion is used for the treatment of non-Hodgkin lymphoma (NHL), chronic lymphocytic leukaemia and rheumatoid arthritis.

MABTHERA 500mg Infusion may also be prescribed for other conditions as determined by the doctor.

How does MABTHERA 500mg Infusion work?

MABTHERA 500mg Infusion belongs to a class of drugs called monoclonal antibodies. It helps in destroying the tumour cells by specifically binding to its receptors. This triggers the immune system and destroys the cancer cells.

MABTHERA 500mg Infusion reduces the inflammation and damage of the joints by binding to the receptors on the B lymphocytes (inflammatory mediators). This improves the joint mobility and reduces the joint pain.  

How to administer MABTHERA 500mg Infusion?

The dosage and the drug form depend on the age, weight and medical condition of an individual.

MABTHERA 500mg Infusion injection is administered only under the supervision of a healthcare provider. Do not self-medicate.

If you miss a dose of MABTHERA 500mg Infusion, consult your doctor immediately.

What are the drugs that interact with MABTHERA 500mg Infusion?

The drugs that interact with MABTHERA 500mg Infusion are:

  • Cholecalciferol
  • Cyanocobalamin
  • Diphenhydramine
  • Duloxetine
  • Hydroxychloroquine
  • Levothyroxine
  • Pregabalin

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of MABTHERA 500mg Infusion?

The following are the most common side effects of MABTHERA 500mg Infusion:

  • Headache
  • Fever
  • Rash
  • Chills
  • Nausea
  • Heartburn
  • Weakness
  • Dizziness
  • Muscle pain
  • Joint pain
  • Increased thirst
  • Throat pain

The following are the severe side effects, and you may require immediate medical attention:

  • Swelling of the hands and feet
  • Increased urination
  • Painful urination
  • Muscle spasms
  • Trouble breathing

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while using MABTHERA 500mg Infusion?

  • Seek doctor’s advice before taking any other drug or herbal products while on MABTHERA 500mg Infusion
  • Avoid consumption of alcohol while on MABTHERA 500mg Infusion
  • Do not drive or operate heavy machinery if MABTHERA 500mg Infusion causes dizziness or blurred vision.
  • Keep the medicine away from children.
  • Tell your doctor if you are pregnant or breastfeeding.

What should you tell your doctor before using MABTHERA 500mg Infusion?

  • Tell your doctor if you are allergic to MABTHERA 500mg Infusion.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Inform your doctor if you have any pre-existing depression, liver or heart diseases.

Frequently Asked questions about MABTHERA 500mg Infusion

  1. How long does it take for MABTHERA 500mg Infusion to work?
  2. Usually, two intravenous infusions are administered with a gap of two weeks, and this is repeated based on the severity of the condition. However, if you begin to respond to MABTHERA 500mg Infusion, you may feel better within 2 – 16 weeks.

  3. Is it common to develop persistent pain or redness at the site of MABTHERA 500mg Infusion injection?
  4. The occurrence of pain or redness is rare with MABTHERA 500mg Infusion injection. However, please consult your doctor immediately.

  5. What are the overdose symptoms of MABTHERA 500mg Infusion?
  6. The overdose symptoms of MABTHERA 500mg Infusion include rash, redness, allergic reaction, muscle stiffness and dizziness. Please consult your doctor if you experience any of the above symptoms.

  7. Can I receive vaccination while on MABTHERA 500mg Infusion?
  8. No, it is not advisable to get vaccinated while using MABTHERA 500mg Infusion. Please consult your doctor.

  9. Is it safe to use MABTHERA 500mg Infusion in case of thrombocytopenia?
  10. No, do not use MABTHERA 500mg Infusion if you have any blood disorders, such as thrombocytopenia. Please inform the doctor about your medical history.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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