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Lymphtor 100mg Injection 1's
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INTRODUCTION
LYMPHTOR 100MG INJECTION contains Bendamustine, which belongs to the group of medicines called Anti-cancer agents. It is used to manage certain forms of cancer, such as chronic lymphocytic leukemia (cancer of the blood and bone marrow), Non-Hodgkin lymphomas (lymph cancer), and multiple myeloma (cancer of plasma cells).
LYMPHTOR 100MG INJECTION can be used either alone or in combination with other anti-cancer agents to achieve better results. Therapy with LYMPHTOR 100MG INJECTION is chosen only when the use of other first-line medicines is not suitable.
The use of LYMPHTOR 100MG INJECTION may cause an abnormal decrease in white blood cells (WBC) and platelet count in the blood. To avoid this, your doctor will closely monitor your blood count periodically before and during treatment with LYMPHTOR 100MG INJECTION.
Before receiving LYMPHTOR 100MG INJECTION, inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have severe bone marrow depression, any infections, or severe changes in white blood cells and platelet count.
LYMPHTOR 100MG INJECTION should not be used in pregnant or breastfeeding women, as it may cause serious harm to the growing fetus or nursing infant. Consult your doctor for advice.
The most common side effects of receiving LYMPHTOR 100MG INJECTION are nausea, vomiting, hair loss, oral sores, diarrhea, constipation, fever, dehydration, headache, and tiredness. Contact your doctor if any of these side effects bother you.
USES OF LYMPHTOR 100MG INJECTION
It is used either alone or in combination with other anticancer medicines to manage:
- Chronic Lymphocytic Leukemia
- Non-Hodgkin’s Lymphoma
- Multiple Myeloma
HOW LYMPHTOR 100MG INJECTION WORKS
LYMPHTOR 100MG INJECTION belongs to an anticancer agent that acts by damaging the genetic material (either DNA or RNA) of cancer cells, which inhibits the cancer cells from growing and multiplying within the body.
DIRECTIONS FOR USE
LYMPHTOR 100MG INJECTION will be administered into the vein only by a doctor or a nurse. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.
SIDE EFFECTS OF LYMPHTOR 100MG INJECTION
COMMON
- headache
- nausea, vomiting
- signs of low red blood cells (weakness, tiredness, dizziness, and shortness of breath)
- signs of low platelet counts (easy bruising or bleeding from gums)
- signs of low white blood cells (repeated fevers and infections)
- mucosal inflammation (oral sores)
- bleeding
- increased or decreased blood pressure
- irregular heart rhythm
- disturbed lung function (cough, shortness of breath, tiredness)
- fever, tiredness
- amenorrhea (missed periods in women)
- diarrhea, constipation, changes in metabolism, and loss of appetite
- dehydration
- hair loss
- skin changes, skin rash, or itching
- sleeping disturbances
- dizziness
- pain, chills
UNCOMMON
- heart attack, chest pain
- heart failure
- fluid accumulation in the heart sac
- acute leukemia (cancer of the blood and bone marrow)
RARE
- drowsiness
- infection of the blood
- loss of voice
- excessive sweating
- acute circulatory collapse (blood circulation problem)
- skin reddening, skin inflammation (dermatitis)
Contact your doctor immediately if you experience any of the following side effects after receiving LYMPHTOR 100MG INJECTION:
- signs of allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, and tongue, causing difficulty breathing or swallowing)
- severe skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis (causing skin peeling, a raised red lesion, and ulcers of the mouth, including the throat, nose, genitals, and eyes)
- medicine-induced allergic reactions (high body temperature, widespread skin rash, and enlarged lymph nodes)
- pain in your side, bloody urine, decreased urine output (signs of tumor lysis syndrome)
- signs of serious brain infection (such as memory loss, difficulty in thinking, difficulty in walking, or vision loss)
- unusual skin changes
HOW TO MANAGE SIDE EFFECTS
Constipation
Include fiber-rich foods in your diet, such as fresh fruits, vegetables, and whole-grain cereals, and drink plenty of fluids. Consult your doctor if your symptoms worsen.
Diarrhea
Drink plenty of fluids, such as water, fruit juices, or electrolytes, to avoid dehydration in your body. Consult your doctor if your symptoms worsen.
Dizziness Or Drowsiness
Lie down until the dizziness passes away, and then move slowly and carefully. Take plenty of rest and drink plenty of fluids. If your symptom does not improve, consult your doctor.
Headache
Try to take a rest. Apply a pain-relieving balm to your forehead. If the symptom does not improve, consult with your doctor.
Skin Rash Or Itching
Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens.
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedLYMPHTOR 100MG INJECTION is not recommended for use in pregnant women as it may cause severe harm to the growing fetus. Women of childbearing age must use a suitable contraceptive before and during management with LYMPHTOR 100MG INJECTION to avoid pregnancy.
BREASTFEEDING
ContraindicatedLYMPHTOR 100MG INJECTION is not recommended for use by breastfeeding women. However, consult your doctor before receiving it. Your doctor may ask you to discontinue breastfeeding if treatment with LYMPHTOR 100MG INJECTION is considered necessary.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate any machines if you experience tiredness, dizziness, or a lack of concentration after receiving LYMPHTOR 100MG INJECTION.
ALCOHOL
ContraindicatedConsumption of alcohol is not recommended during treatment with LYMPHTOR 100MG INJECTION.
KIDNEY
Consult your doctorLYMPHTOR 100MG INJECTION is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with mild to moderate kidney impairment. Consult your doctor before receiving it.
LIVER
Consult your doctorLYMPHTOR 100MG INJECTION is not recommended for use in patients with moderate to severe liver impairment (jaundice). It should be used with caution in patients with mild liver dysfunction. Consult your doctor before receiving it.
ALLERGY
ContraindicatedDo not receive LYMPHTOR 100MG INJECTION if you are allergic to Bendamustine or any other ingredients of this medicine.
LUNGS
Use with CautionLYMPHTOR 100MG INJECTION should be used with caution in patients with respiratory diseases such as bronchitis. Consult your doctor before receiving it.
HEART DISEASE
Use with CautionLYMPHTOR 100MG INJECTION should be used with caution in patients with heart disease (such as chest pain, heart attack, or irregular heart rhythm). Consult your doctor before receiving it.
USE IN PEDIATRICS
Consult your doctorThe safety and effectiveness of LYMPHTOR 100MG INJECTION in children have not been established. Consult your doctor for advice.
USE IN GERIATRICS
Use with CautionLYMPHTOR 100MG INJECTION should be used with caution with elderly patients. Consult your doctor before receiving the medicine.
OTHERS
LYMPHTOR 100MG INJECTION is not recommended for use if you:
- have bone marrow depression
- have serious changes in white blood cells or platelet counts in the blood
- have recently had or had any major surgery (less than 30 days before starting this treatment)
- have an infection accompanied by a low white blood cell count
Before receiving LYMPHTOR 100MG INJECTION, inform your doctor if you:
- have signs or symptoms of infection (fever, weakness, body pain, including lungs symptoms such as cough, shortness of breath, wheezing, or chest pain)
- have any skin reactions or light sensitivity
INTERACTIONS
A. Drug-Drug Interactions:
Before receiving LYMPHTOR 100MG INJECTION, inform your doctor if you are taking any of the following medicines:
- medicines used to manage stomach ulcers (Ex. omeprazole, esomeprazole)
- ciprofloxacin (used to manage bacterial infections)
- fluvoxamine (used to manage obsessive-compulsive disorder)
- vaccines used to inhibit viral infections (cholera live vaccine, H1N1 live vaccine, zoster live vaccine)
- methotrexate (used to manage psoriasis or rheumatoid arthritis)
- yellow fever vaccine (used to protect against yellow fever)
Overdosage:
LYMPHTOR 100MG INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
SYNOPSIS
| Drug | : | Bendamustine |
| Pharmacological Category | : | Alkylating agents |
| Therapeutic Indication | : | Chronic lymphocytic leukemia, Non-Hodgkin’s Myeloma, Multiple Myeloma |
| Dosage Forms | : | Injection |
MORE INFORMATION
- Keep LYMPHTOR 100MG INJECTION out of reach of children
- Store at a temperature not exceeding 35°C
FAQs ABOUT LYMPHTOR 100MG INJECTION
Q: What is the use of LYMPHTOR 100MG INJECTION?
A: LYMPHTOR 100MG INJECTION is an anticancer medicine used to manage certain forms of cancer, such as chronic lymphocytic leukemia (cancer of the blood and bone marrow), Non-Hodgkin lymphomas (lymph cancer), and multiple myeloma (cancer of plasma cells).
Q: Is LYMPHTOR 100MG INJECTION chemotherapy?
A: Yes. LYMPHTOR 100MG INJECTION is chemotherapy. It acts by inhibiting the growth and multiplication of cancer cells within the body.
Q: Is the use of LYMPHTOR 100MG INJECTION safe?
A: LYMPHTOR 100MG INJECTION is safe when used under proper medical supervision and at the prescribed doses.
Q: What are the side effects of LYMPHTOR 100MG INJECTION?
A: LYMPHTOR 100MG INJECTION may cause an abnormal decrease in white blood cells and platelet counts. It may also cause nausea, vomiting, headache, dizziness, tiredness, mouth sores, fever, hair loss, and skin changes. Consult your doctor for advice if the side effects persist for a longer duration.
Q: Can the use of LYMPHTOR 100MG INJECTION cause skin damage?
A: Yes. The use of LYMPHTOR 100MG INJECTION may cause unusual changes in the skin. Consult your doctor immediately if you notice any unusual skin changes.
Q: How does LYMPHTOR 100MG INJECTION work?
A: LYMPHTOR 100MG INJECTION belongs to an anticancer agent that acts by damaging the genetic material (either DNA or RNA) of cancer cells, which inhibits the cancer cells from growing and multiplying within the body.
Q: Can the use of LYMPHTOR 100MG INJECTION cause hair loss?
A: Yes. Hair loss is one of the common side effects of taking a chemotherapy medicine like LYMPHTOR 100MG INJECTION. Consult your doctor if it bothers you.
Q: Can the use of LYMPHTOR 100MG INJECTION cause constipation?
A: Yes. LYMPHTOR 100MG INJECTION may cause constipation in some individuals. If you experience constipation, include plenty of fiber-rich foods (such as cereals, pulses, and fruits) in your diet. Drink plenty of water. If it bothers you, consult your doctor.
REFERENCES
1. Guido Marcucci, Meir Wetzler, John C. Byrd, Krzysztof Mrózek, and Clara D. Bloomfield. Leukemias. Textbook of Medical Oncology. 4th Edition. 2009. Edited by Franco Cavalli Stan B Kaye Heine H Hansen James O Armitage Martine J Piccart-Gebhart. Informa Healthcare. Page – 229.
2. RS Satoskar, SD Bhandarkar, Nirmala N. Rege. Alkylating agents. Chemotherapy of Malignancy. Pharmacology and Pharmacotherapeutics. 24th Edition. 2015. Page – 1274.
3. Martina Bogeljic Patekar, Vibor Milunovic, Karla Misura Jakobac, Drazen Perica, Inga Mandac Rogulj, Marin Kursar, Ana Planinc-Peraica, and Slobodanka Ostojic Kolonic. Bendamustine: an old drug in the new era for patients with Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia. NIH. National Library of Medicine. National Center for Biotechnology Information. September 2018. [Accessed on 3rd September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536274/
4. Ibrahim T Aldoss, Susan M Blumel, and Philip J Bierman. The role of Bendamustine in the treatment of indolent non-Hodgkin lymphoma. NIH. National Library of Medicine. National Center for Biotechnology Information. November 2009. [Accessed on 3rd September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004665/
5. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 3rd September 2022] https://www.medicines.org.uk/emc/files/pil.5095.pdf
6. Cephalon, Inc. U.S. Food & Drug Administration. [Revised in October 2008] [Accessed on 3rd September 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022303lbl.pdf
7. Central Drugs Standard Control Organization. Bendamustine. [Revised in September 2014]. [Accessed on 3rd September 2022] https://cdscoonline.gov.in/CDSCO/Drugs
USEFUL DIAGNOSTIC TESTS
- Cd117 (Myeloid Cell Marker)
- Fish-Multiple Myeloma
- Acute Leukemia - Mrd Panel (Mrd & Relapse)
- Chromosome Analysis, Leukemic Blood
AUTHOR DETAILS
Written By Dr. N. Sai Swaroop, Pharm.D
Last updated on 27 Nov 2023 | 03:30 PM(IST)
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.