Lupigest 400mg Capsule 10'S

Hormonal Therapy Rx required

Best Price*  ₹ 464.68
MRP ₹580.85
(Inclusive of all taxes) *10 Capsule(s) in a Strip * Mfr: Lupin Ltd * Country of Origin: India
TOTAL AMOUNT ₹ 580.85

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INTRODUCTION

LUPIGEST 400MG contains Progesterone which belongs to the group of medicine called progestins. It is used to treat secondary amenorrhea in adult females. Secondary amenorrhea is a condition of absence of menstruation for three months or longer after having at least one menstrual period. It is typically caused due to hormonal imbalance. Progesterone helps to maintain normal hormonal balance and provides relief from menstrual disorders and infertility issues. Along with the treatment, your doctor might recommend you eat a healthy diet rich in fruits, greens and vegetables. Try to exercise regularly and reduce your stress levels. If you are over-weight or obese, reduce your extra weight, which might help you see the results faster.

The most common side effects of taking this medicine are headache, dizziness, stomach pain, bloating and breast pain. Contact your doctor immediately, if you see any changes in breasts like dimpling of the skin, changes in the nipple or presence of any lumps. Avoid consumption of alcohol, driving or travelling, because this medicine may make you feel dizzy and drowsy. Before taking this medicine, inform your doctor if you have severe liver or heart problems. This medicine is not recommended for use in patients who have cancer in the breast or uterus, blood clotting disorders or unexplained vaginal bleeding. Consult your doctor before taking. LUPIGEST 400MG should be used with caution in pregnant and breastfeeding women. Consult your doctor before taking. This medicine is intended for use only in adult females and not recommended for use in children.

USES OF LUPIGEST 400MG

  • Treats secondary amenorrhea in adult females

HOW LUPIGEST 400MG WORKS

Progesterone taken orally, binds to and activates the progesterone receptor (PR) present in the stromal cells during the secretory phase of menstrual cycle and during pregnancy. It works by adjusting the hormonal balance within the body, restores progesterone levels in case of deficiency and reduce the symptoms associated with menstrual disorders.

DIRECTIONS FOR USE

Take LUPIGEST 400MG as directed by your physician. Take this medicine daily at bedtime before meals for 10 days. Swallow the medicine as a whole with a sip of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results

SIDE EFFECTS OF LUPIGEST 400MG

SERIOUS

  • stroke, heart attack
  • visual loss or blindness
  • changes in speech
  • severe pains in legs
  • chest pain with or without shortness of breath, weakness and fatigue

COMMON

  • drowsiness, dizziness
  • breast tenderness or pain
  • abdominal cramps or bloating
  • headaches
  • irregular vaginal bleeding or spotting
  • nausea and vomiting
  • hair loss
  • fluid retention (edema)
  • vaginal yeast infection

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Bloating or wind:

Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptoms get worse, contact your doctor immediately.

Abdominal cramps:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

Headache:  

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

WARNING & PRECAUTIONS

PREGNANCY

LUPIGEST 400MG should be used with caution in pregnant women. Consult your doctor before taking this medicine.

BREASTFEEDING

LUPIGEST 400MG should be used with caution if you are breastfeeding women. Consult your doctor before taking this medicine.

DRIVING AND USING MACHINES

Do not drive or operate any machines, because this medicine may make you feel dizzy.

ALCOHOL

Avoid consumption of alcohol while taking this medicine, because it can increase the risk of side effects.

KIDNEY

LUPIGEST 400MG should be used with caution in patients with kidney disease. Consult your doctor for advice.

LIVER

LUPIGEST 400MG should be used with caution in patients with liver disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to progesterone.

LUNGS

LUPIGEST 400MG should be used with caution in patients with asthma or other respiratory disorders. Consult your doctor for advice.

HEART DISEASE

LUPIGEST 400MG should be used with caution in patients with heart problems. Consult your doctor for advice.

OTHERS

Tell your doctor, before taking this medicine if you:

  • have breast cancer or cancer that is sensitive to estrogen (e.g. endometrial cancer)
  • have unexplained vaginal bleeding
  • have or ever had blood clotting disorders (e.g. blood clot in the vein or legs)
  • have diabetes
  • have high blood pressure
  • have migraine headache
  • have systemic lupus erythematosus (allergic immune reaction)
  • have epilepsy
  • have depression
  • are elderly (aged 65 years and above)

INTERACTIONS

Talk to your doctor, if you are taking,

  • medicines used to treat epilepsy (e.g. phenytoin, phenobarbital, carbamazepine)
  • medicines used to treat tuberculosis (e.g. rifampicin, rifabutin)
  • medicines used to prevent blood clots (e.g. coumarins, phenindone)
  • medicines used to treat fungal infection (e.g. ketoconazole, griseofulvin or terbinafine)
  • medicines used to treat diabetes (e.g. insulin, metformin)
  • St. John’s Wart (a herbal medicine to treat depression)
  • bromocriptine (used to treat problems of pituitary gland or Parkinson’s disease)
  • ciclosporin (used to suppress immune system)

SYNOPSIS

Drug :   Progesterone
Pharmacological Category :   Progestins
Therapeutic Indication :   Secondary amenorrhea
Dosage Forms :   Tablet, Capsule, Gel, Ointment, Injection, Pessary, Spray

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT LUPIGEST 400MG

Can LUPIGEST 400MG cause miscarriage?

Currently, there is no evidence that progesterone as oral medication can cause miscarriage. If you are experiencing any unusual symptoms after taking this medicine, contact your doctor.

Can LUPIGEST 400MG cause headache?

Yes. This medicine can cause headache in some individuals, although not everybody gets them. Rest and drink plenty of fluids. Do not drink too much alcohol. If the symptom persists, contact your doctor.

REFERENCES

1. KD. Tripathi. Hormones and related drugs: Estrogens, Progestins and Contraceptives. Essentials of medical pharmacology. Seventh edition. 2013. Page – 316-319.

2. Ellis R. Levin and Stephen R. Hammes. Estrogens and Progestins. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1180-1184.

3. University of British Columbia. Progesterone for Perimenopausal Night Sweats. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on December 2019] [Accessed 10th November 2020] https://clinicaltrials.gov/ct2/show/NCT01464697

4. IBSA Institut Biochimique SA. Efficacy Study of Progesterone Tablet in Post-menopausal Women. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on June 2018] [Accessed 10th November 2020] https://clinicaltrials.gov/ct2/show/NCT02841137

5. Katrina Wyatt, Paul Dimmock, Peter Jones, Manjit Obhrai, and Shaughn O'Brien. Efficacy of progesterone and progestogens in management of premenstrual syndrome: systematic review. NCBI; PMC National Library of Medicine, National Institute of Health. October 2001. [Accessed 10th November 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC57352/

6. D L Moyer, B de Lignieres, P Driguez, J P Pez. Prevention of endometrial hyperplasia by progesterone during long-term estradiol replacement: influence of bleeding pattern and secretory changes. NIH National Library of Medicine, National Centere of Biotechnology Information. Pubmed.gov. May 1993. [Accessed 10th November] https://pubmed.ncbi.nlm.nih.gov/8486201/#:~:text=Conclusions%3A%20Control%20of%20endometrial%20growth,benefit%20for%20prevention%20of%20hyperplasia.

7. Ciplamed. Endogest capsules (micronized progesterone). Ciplamed.com [Revised on December 2015] [Accessed 10th November 2020] https://www.ciplamed.com/content/endogest-capsules

8. Catalent Pharma Solutions. U.S. Food & Drug Administration. 2011. [Accessed 9th November 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019781s017,020843s011lbl.pdf

9. Besins Manufacturing Belgium. Electronic Medicines Compendium (EMC); [Revised on May 2020] [Accessed 9th November 2020] https://www.medicines.org.uk/emc/files/pil.352.pdf

USEFUL DIAGNOSTIC TESTS

  • Anti-Mullerian Hormone
  • Glycosylated Hemoglobin
  • Testosterone Total
  • Thyroid Stimulating Hormone

Manufacturer/Marketer Details

    Net Qty
    1
    Shelf Life
    NA
    Item Weight
    17.5
    No. of Units in a Kit
    NA
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Lupigest 400mg Capsule 10'S

Lupigest 400mg Capsule 10'S Mfr: Lupin Ltd

M.R.P.: Rs.580.85
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