LUPIFLEX 8mg Tablet is used for the treatment of dorsal pain and low back pain. It is also recommended in the treatment of torticollis and degenerative vertebral disorders.

LUPIFLEX 8mg Tablet may also be prescribed for other conditions as determined by the doctor.

In LUPIFLEX 8mg Tablet, Ketoprofen belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). Prostaglandins are the hormone-like substances, which causes inflammation and pain. Ketoprofen acts by reducing the levels of prostaglandins. Thus, it decreases pain and swelling.

Thiocolchicoside belongs to the class of drugs called as muscle relaxants. This drug acts by antagonizing the activity of certain receptors in the brain (GABA and glycine receptor). Thus, it relieves muscle stiffness and spasm.

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take LUPIFLEX 8mg Tablet as prescribed by your doctor.

Swallow the whole tablet. Do not crush or chew the tablet. Take the drug with or without food. However, taking the drug with food prevents stomach upset.

The overdose symptoms of LUPIFLEX 8mg Tablet include the following:

• Light-headedness
• Shallow breath
• Discomfort in chest

Drugs that interact with LUPIFLEX 8mg Tablet include the following:

• Citalopram
• Escitalopram
• Fluoxetine
• Fluvoxamine
• Iopamidol
• Lithium
• Methotrexate
• Paroxetine
• Sodium Bisphosphate
• Tacrolimus
• Vilazodone
• Warfarin

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

The following are the most common side effects of LUPIFLEX 8mg Tablet:

• Abdominal pain
• Diarrhoea
• Drowsiness
• Nausea
• Vomiting

The following are the severe side effects, and you may require immediate medical attention:

• Depression
• Peptic ulcer
• Bronchospasm
• Dyspepsia
• Fainting
• Stomach bleeding

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

• Avoid using the medicine if you are allergic to LUPIFLEX 8mg Tablet or similar drugs.
• Avoid consumption of alcohol as it may worsen the side effects of LUPIFLEX 8mg Tablet.
• Seek doctor’s advice before taking any other drug or herbal products while on LUPIFLEX 8mg Tablet.
• Be cautious while taking LUPIFLEX 8mg Tablet if you have any kidney or liver impairment.
• Keep the medication out of reach of children.
• Do not exceed the dose more than prescribed.

You are advised not to take LUPIFLEX 8mg Tablet if:

• it has passed the expiry date of the medicine printed on the pack.
• the foil or packaging is torn or shows signs of tampering or there is discolouration.

• Tell your doctor if you have any history of heart, liver, kidney, or lung diseases.
• Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
• Inform the doctor if you are pregnant or breastfeeding.

1. Is it safe to use LUPIFLEX 8mg Tablet in patients with heart disease?

Use of LUPIFLEX 8mg Tablet should be avoided by the patients with heart disease, as it may increase the risk of stroke.

2. How long can I take LUPIFLEX 8mg Tablet?

The duration of the treatment depends on the severity of your condition. However, use of LUPIFLEX 8mg Tablet for long-term may increase the risk of stomach bleeding and kidney problems.

3. Is it safe to use LUPIFLEX 8mg Tablet in peptic ulcer patients?

No. It is not safe to use LUPIFLEX 8mg Tablet, as this drug worsens the condition of peptic ulcer.

4. Should I follow any special dietary instructions while taking LUPIFLEX 8mg Tablet?

Follow a regular diet while taking LUPIFLEX 8mg Tablet unless any special dietary instructions are suggested by the doctor.