LUMETHER DT 40 Tablet 6's

Malarial Rx required

Best Price* ₹ 108.32 MRP ₹ 120.36
(Inclusive of all taxes) *6 Tablet(s) in a Strip * Mkt: Themis Medicare Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

LUMETHER DT 40 TABLET is a combination of Artemether and Lumefantrine which belongs to the group of medicines called Antimalarials. It is used in infants, children and adults for the treatment of acute uncomplicated malaria (mosquito borne disease with symptoms of fever with chills, tiredness, nausea, vomiting, stomach pain) caused by a parasite called plasmodium falciparum.  

LUMETHER DT 40 TABLET should be used with caution in patients with severe liver or kidney problems or if the patient feels worse or unwell to eat and drink.

LUMETHER DT 40 TABLET is not recommended for use in patients having severe type of malarial infection affecting the lungs, kidney or brain, heart condition such as changes in the heart rhythm, slow heartbeat or severe heart disease and low levels of electrolytes such as potassium or magnesium in the blood.

LUMETHER DT 40 TABLET is generally not recommended for use during the first trimester of pregnancy and it should be used with caution during the second and third trimester of pregnancy and breast-feeding women only if advised by the doctor.  

LUMETHER DT 40 TABLET should be used with caution in children and your child’s doctor may adjust the dose depending upon child’s age and body weight.

The most common side effects of taking LUMETHER DT 40 TABLET are headache, dizziness, vomiting, stomach pain, nausea, muscle pain and loss of appetite. Consult your doctor if any of the side effects worsen.

USES OF LUMETHER DT 40 TABLET

  • Treats acute uncomplicated malarial infections (caused by plasmodium falciparum) in infants, children and adults

HOW LUMETHER DT 40 TABLET WORKS

LUMETHER DT 40 TABLET effectively treats malarial infections, where artemether effectively kills the malarial parasites by binding to haem (part of molecules that contains iron which is toxic to malarial parasites) which is produced during the breakdown of haemoglobin. Lumefantrine works by binding to hemin where it prevents the formation of a toxic malarial pigment called hemozoin, thereby it treats malarial infection. In addition to this artemether and lumefantrine blocks nucleic acid and protein synthesis in parasite that damages the parasitic cell membrane of plasmodium falciparum which leads to the death of parasite. Thus, it helps in treating the malarial infection.

DIRECTIONS FOR USE

Take LUMETHER DT 40 TABLET exactly as advised by your doctor.

For Tablet, Capsule: Swallow LUMETHER DT 40 TABLET with a glass of water. This medicine should be taken with food or drinks rich in fat such as milk. Crush the medicine into powder if your child is unable to swallow the whole medicine.

For Dispersible Tablet: Disperse LUMETHER DT 40 TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.

Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the disease condition.

SIDE EFFECTS OF LUMETHER DT 40 TABLET

COMMON

  • headache, dizziness
  • nausea, vomiting
  • stomach pain
  • diarrhea
  • muscle or joint pain
  • difficulty to sleep
  • loss of appetite
  • cough
  • fast heartbeat
  • general weakness, tiredness
  • involuntary muscle spasms
  • abnormal walking (in children above 12 years)
  • tingling sensation or numbness of hand and feet
  • rashes or itching in the skin
  • disturbance in heart rhythm (prolonged QTc interval)

UNCOMMON

  • sleepiness
  • decreased skin sensitivity
  • inability to coordinate movements

RARE

  • allergic reactions

Stop taking LUMETHER DT 40 TABLET and contact your doctor immediately if you experience any of the following side effects:

  • swelling of the face, lips, tongue or throat with difficulty in breathing and swallowing
  • skin condition with large fluid filled blisters (bullous eruption)

HOW TO MANAGE SIDE EFFECTS

Headache:  

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if required. Do not consume too much of alcohol. Consult your doctor if the symptom does not improve.

Nausea and vomiting:

Stick to simple meals while taking this medicine. Avoid eating oily, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve. 

Stomach pain:

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom does not improve. 

Diarrhea:

Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom does not improve.

Tiredness:

Drink plenty of fluid and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY

LUMETHER DT 40 TABLET is generally not recommended for use during the first trimester of pregnancy. It should be used with caution during second and third trimester of pregnancy only if considered clearly necessary. Consult your doctor before taking LUMETHER DT 40 TABLET.

BREASTFEEDING

LUMETHER DT 40 TABLET should be taken with caution in breast feeding women only if considered clearly necessary. Consult your doctor before taking LUMETHER DT 40 TABLET.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you experience dizziness, sleepiness or weakness after taking LUMETHER DT 40 TABLET.

KIDNEY

LUMETHER DT 40 TABLET is not recommended for use in patients having severe type of malarial infection affecting the kidneys. It should be taken with caution in patients with severe kidney problems. Consult your doctor before taking LUMETHER DT 40 TABLET.

LIVER

LUMETHER DT 40 TABLET should be taken with caution in patients with severe liver problems. Consult your doctor before taking LUMETHER DT 40 TABLET.

ALLERGY

Do not take LUMETHER DT 40 TABLET if you are allergic to Artemether, Lumefantrine or any other ingredients of this medicine.

LUNGS

LUMETHER DT 40 TABLET is not recommended for use in patients having malaria with pulmonary edema or severe type of malarial infection affecting the lungs. Consult your doctor before taking it.

HEART DISEASE

LUMETHER DT 40 TABLET is not recommended for use in patients with severe heart disease or with heart diseases such as slow heartbeat, changes in the rhythm or rate of the heartbeat or family history of death due to heart problems or born with heart problems. LUMETHER DT 40 TABLET should be taken with caution in patients with variations in ECG (prolongation of QTc interval). Consult doctor before taking LUMETHER DT 40 TABLET.

OTHERS

LUMETHER DT 40 TABLET is not recommended for use if you have:

  • severe type of malarial infection that has affected the brain
  • low levels of electrolytes such as potassium or magnesium in blood

Before taking LUMETHER DT 40 TABLET, inform your doctor if you:

  • infected with both the plasmodium falciparum and plasmodium vivax parasites
  • feeling worse or if you feel too unwell to eat and drink

Use in pediatrics

LUMETHER DT 40 TABLET should be given with caution in children as the dosages of LUMETHER DT 40 TABLET vary in children according to their body weight. So, consult a paediatrician before you give this medicine to your child.

Use in geriatrics

LUMETHER DT 40 TABLET can be used in elderly patients. However, consult your doctor before taking this medicine.

INTERACTIONS

A. Drug – drug interactions:

Before taking LUMETHER DT 40 TABLET, inform your doctor if you are taking any of the following medicines:

  • medicines used to treat heart rhythm problems (Ex. Flecainide, metoprolol)
  • medicines used to treat depression (Ex. imipramine, amitriptyline, clomipramine, St. John’s wort)
  • medicine used to treat leprosy or tuberculosis (Ex. rifampicin)
  • medicines used to treat bacterial infections (EX.  fluroquinolones such as ciprofloxacin, levofloxacin, macrolide antibiotics like azithromycin, erythromycin)
  • medicines used to treat fungal infection (Ex. ketoconazole, fluconazole, itraconazole)
  • medicines used to treat allergy (Ex. terfenadine, astemizole)
  • medicine used to treat stomach disturbance (Ex. cisapride)
  • medicines used to treat fits (Ex. carbamazepine, phenytoin)
  • medicines used to treat malaria (Ex.  atovaquone/proguanil, chloroquine)
  • medicines used to treat HIV infection (Ex. indinavir, ritonavir)
  • medicine used to prevent pregnancy (Ex. Ethinyl estradiol)

B. Drug – Food interactions

Drink grapefruit juice with caution while taking LUMETHER DT 40 TABLET as it may interact with this medicine.

Overdosage:

If you or anyone else accidentally take too much of LUMETHER DT 40 TABLET, consult your doctor immediately or visit a nearby hospital.

SYNOPSIS

Drug :   Artemether, Lumefantrine
Pharmacological Category :   Antimalarials
Therapeutic Indication :   Treats acute uncomplicated malaria
Dosage Forms :   Tablet, Dispersible tablet, Injection, Syrup, Oral suspension, Dry Syrup

MORE INFORMATION

  • Keep LUMETHER DT 40 TABLET out of reach of children
  • Store LUMETHER DT 40 TABLET at room temperature

FAQs ABOUT LUMETHER DT 40 TABLET

What is LUMETHER DT 40 TABLET used for?

LUMETHER DT 40 TABLET is used in infants, children and adults for the treatment of acute uncomplicated malaria (mosquito born disease with symptoms of fever with chills, tiredness, nausea, vomiting, stomach pain) caused by a parasite called plasmodium falciparum.

Does LUMETHER DT 40 TABLET helps to prevent malaria?

LUMETHER DT 40 TABLET is not used to prevent malaria. It is only used to treat malarial infection caused by a parasite called plasmodium falciparum. Consult your doctor for advice before taking this medicine.

Is LUMETHER DT 40 TABLET safe to use in pregnant women?

LUMETHER DT 40 TABLET is generally not recommended for use during the first trimester of pregnancy. It should be used with caution during second and third trimester of pregnancy only if considered clearly necessary. Consult your doctor before taking LUMETHER DT 40 TABLET.

Can LUMETHER DT 40 TABLET be used in patients with kidney problems?

LUMETHER DT 40 TABLET is not recommended for use in patients having severe type of malarial infection affecting the kidneys. It should be taken with caution in patients with severe kidney problems. Consult your doctor before taking LUMETHER DT 40 TABLET.

Does LUMETHER DT 40 TABLET cause diarrhea?

Yes, LUMETHER DT 40 TABLET may cause diarrhea in some individuals. To manage this effect, drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom does not improve.

REFERENCES

1. KD Tripathi. Antimalarial drugs. Essentials of Medical Pharmacology. Eighth edition. 2019. Page: 875-77.

2. Stephan Ehrhardt, Christian G Meyer. Artemether–lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria. NIH. National Library of medicine. National center for Biotechnology Information. PubMed central. October 2009. [Accessed on 3rd November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762439/

3. Novartis Pharmaceuticals. Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria (CALINA). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in March 2020] [Accessed on 3rd November 2022] https://clinicaltrials.gov/ct2/show/NCT04300309

4. Novartis Ireland Limited. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 3rd November 2022] https://www.medicines.org.uk/emc/files/pil.1628.pdf

5. Ajanta Pharma Ltd. Food and Drugs Authority (FDA).[Revised in February 2018] [Accessed on 3rd November 2022] https://fdaghana.gov.gh/img/smpc/Artefan%20(Artemether-Lumefantrine%2060mg-360mg)%20Tablets.pdf

6. Ajanta Pharma Ltd. Artefan 80/480 (Artemether and Lumefantrine). [Revised in March 2019] [Accessed on 3rd November 2022] https://extranet.who.int/pqweb/sites/default/files/MA130part3.pdf

7. Ajanta Pharma Ltd. Artefan 40/240 (Artemether and Lumefantrine). [Revised in March 2019] [Accessed on 3rd November 2022] https://extranet.who.int/pqweb/sites/default/files/MA128part3.pdf

8. Getz pharma ltd. Artheget (Artemether + Lumefantrine). [Accessed on 3rd November 2022] https://getzpharma.com/wp-content/uploads/2016/07/Artheget-Range-Leaflet-Pakistan.pdf

9. Cipla Ltd. Lumet 80 Tablets (Artemether + Lumefantrine). CiplaMed. [Revised in October 2013] [Accessed on 3rd November 2022] https://ciplamed.com/content/lumet-80-tablets

USEFUL DIAGNOSTIC TESTS

  • Peripheral Smear for Malaria

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    15 g
    Ingredient
    ARTEMETHER 40 mg+LUMEFANTRINE 240 mg
    Hsn Code
    30049059
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LUMETHER DT 40 Tablet 6's

LUMETHER DT 40 Tablet 6's Mkt: Themis Medicare Ltd

M.R.P.: Rs.120.36
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