LISUPRIL 10 Tablet 15's

Hypertension Rx required

Best Price* ₹ 108.00 MRP ₹ 135.00
(Inclusive of all taxes) *15 Tablet(s) in a Strip * Mkt: PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

LISUPRIL 10 contains Lisinopril which belongs to group of medications called Angiotensin converting enzyme (ACE) inhibitors. LISUPRIL 10 is used in the treatment of hypertension (a condition in which force of the blood against the blood vessel is too high that causes headaches in the early morning, bleeding in nose, tiredness, nausea, vomiting, chest pain, vision changes, and buzzing in the ears).  

It is also used to treat heart failure (heart cannot supply enough blood leading to shortness of breath, and swelling of legs, ankle, and feet), heart attack (blockage of blood flow to the heart muscle characterized by severe pain in the chest along with fatigue and excessive sweating) and kidney problems associated with diabetic patients who have high blood pressure.   

Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor that reduces the high blood pressure by inhibiting the activity of an enzyme called Angiotensin converting enzyme (an enzyme which is responsible for causing constriction of blood vessels) which enhances easy flow of blood around the body and reduces the workload of the heart. Your doctor may test your kidney function, blood pressure, and the electrolyte level (Ex. potassium) in your blood at regular intervals, while taking LISUPRIL 10.

Before taking LISUPRIL 10, inform your doctor if you have low blood pressure (hypotension), heart failure or heart valve disease (stenosis) or thickening of the arteries of your heart or an enlarged heart (hypertrophic cardiomyopathy), had a stroke earlier, have kidney disease (stenosis) or undergoing treatment (dialysis treatment or a transplant).

LISUPRIL 10 should be avoided among women who are pregnant or breastfeeding. It is not recommended in children under 6 years of age or in any child with severe kidney problems. The most common side effects of LISUPRIL 10 are dizziness, headache, dry cough, nausea, vomiting and diarrhoea. Consult your doctor if any of the symptoms worse.

USES OF LISUPRIL 10

  • Treats high blood pressure
  • Treats heart failure
  • Treat patients who had heart attack recently
  • Treats kidney problems in diabetic patients with high blood pressure  

HOW LISUPRIL 10 WORKS

LISUPRIL 10 works by decreasing certain chemicals to widen the blood vessel for increased blood flow and thereby reducing the effort of heart to pump blood around the body. This combined action will be beneficial in the treatment of hypertension, heart failure, heart attack and slows down the progression of kidney diseases in diabetic patients (diabetic nephropathy) with high blood pressure. LISUPRIL 10 also maintains the blood pressure level for a longer time.

DIRECTIONS FOR USE

Take LISUPRIL 10 as advised by your physician. Swallow LISUPRIL 10 with a glass of water and do not crush or chew it. Your doctor will decide the correct dose for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF LISUPRIL 10

COMMON

  • headache
  • dizziness
  • diarrhea
  • cough
  • vomiting

UNCOMMON

  • mood changes
  • fingers or toes color change to pale blue (blood circulation problem)
  • prickling or tingling sensation in fingers or toes.
  • taste changes
  • head spinning feeling (vertigo)
  • difficulty in falling asleep
  • faster heartbeat (palpitations)
  • running nose
  • stomach pain or indigestion
  • skin rash or itching sensation
  • unable to get an erection (erectile dysfunction)
  • tiredness or weakness

RARE

  • confusion
  • changes in smell sensation
  • dry mouth
  • skin disease with thickened red patches mixed with silvery scales (psoriasis).
  • hair loss                 
  • painful joints (due to high uric acid levels)
  • breast enlargement in men (gynecomastia)
  • anemia
  • signs of low sodium levels in blood (tiredness, weakness, confusion, fluid retention)

Stop taking LISUPRIL 10 and consult your doctor immediately if you experience any of the following side effects:

  • signs of heart attack (severe sudden chest pain that might spread to the neck, shoulders and arms with shortness of breath and sweating)
  • signs of stroke (weakness or numbness in one side of the body along with confusion, difficulty speaking or loss of coordination)
  • severe allergic reactions (swelling of the hands, face, lips, tongue and/or throat, cause difficulty in breathing or swallowing (angioedema) or breathing difficulty and wheezing with severe itching sensation of the skin (anaphylaxis) or blistering and peeling of the skin, mouth, eyes and genital organs (pemphigus, Stevens-Johnson syndrome or if widespread, toxic epidermal necrolysis)]
  • signs of kidney failure (sudden reduction in the urine output or cloudy urine or blood in the urine along with lower back pain, nausea, vomiting or swelling in your legs, ankles or feet)
  • signs of pancreatitis (severe abdominal pain radiating to the back with vomiting)
  • signs of liver problems [yellowing of your skin or whites of the eyes (jaundice), dark urine, pale stools, tiredness, fever, nausea, stomach pain and weakness]
  • signs of a low immunity (frequent incidence of infections resulting in fever, severe chills, sore throat or mouth ulcers)
  • signs of reduced production of blood cells (frequent appearance of bruise or bleed more easily or without explanation, or yellowing of the skin or eyes or feel tired, pale or weak)

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Sit down or lie down slowly when you are feeling dizziness. Take rest for some time and drink plenty of water. Avoid coffee and other carbonated drinks. If the symptom does not improve, contact your doctor.

Dry cough:

Drink plenty of liquids to stay hydrated and gargle with lukewarm saltwater to soothe the irritated throat. You can also try hot tea or water with honey and lemon. If the symptom does not improve, contact your doctor.

Headache:

Try to rest and relax. Apply pain balm to the head to ease off the pain. Sip on some hot water or ginger tea. If the symptom does not improve, contact your doctor.

Diarrhoea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

WARNING & PRECAUTIONS

PREGNANCY

LISUPRIL 10 is not recommended for use in early pregnancy and should be avoided after 3 months pregnant, as they may cause serious harm to your baby, especially if used after the third month of pregnancy. Consult your doctor for advice before LISUPRIL 10.

BREASTFEEDING

LISUPRIL 10 is not recommended for use among breastfeeding women. Consult your doctor before taking LISUPRIL 10, your doctor may choose another treatment if you want to continue breast-feeding.

DRIVING AND USING MACHINES

Do not drive or operate any machines, if you feel dizzy or tired while taking LISUPRIL 10. Consult your doctor before taking LISUPRIL 10.  

ALCOHOL

Avoid consumption of alcohol while taking LISUPRIL 10, as it could aggravate your existing condition. Consult your doctor before taking LISUPRIL 10.

KIDNEY

LISUPRIL 10 should be used with caution in patients with kidney disease, improper functioning of the kidneys or narrowing (stenosis) of the blood vessels to the kidney and in patients undergoing dialysis or had kidney transplantation. Consult your doctor before taking LISUPRIL 10.

LIVER

LISUPRIL 10 should be used with caution in patients with liver problems. Consult your doctor for advice before taking LISUPRIL 10.

ALLERGY

LISUPRIL 10 is not recommended for use if you are allergic to lisinopril, or any other angiotensin converting enzyme (ACE) inhibitors such as captopril, ramipril.

HEART DISEASE

 

LISUPRIL 10 should be used with caution in patients with low blood pressure, abnormal functioning of the heart, heart failure or heart valve disease, narrowing (stenosis) or hardening of the arteries of your heart or an enlarged heart (hypertrophic cardiomyopathy). Consult your doctor for advice before taking LISUPRIL 10.

OTHERS

LISUPRIL 10 is not recommended for use if you have:

  • hereditary angioedema
  • idiopathic angioedema  

Before taking LISUPRIL 10, inform your doctor if you:

  • are dehydrated (due to dialysis treatment, dietary restriction of salt, vomiting or diarrhoea)
  • have diabetes
  • have high levels of potassium in your blood (hyperkalaemia)
  • had a stroke or mini-stroke (also known as transient ischaemic attack) (TIA)
  • are under blood separation treatment (apheresis) for high cholesterol levels or under desensitization treatment for wasp or bee sting
  • have collagen vascular disease Ex. Scleroderma or lupus

Use in Pediatrics:

LISUPRIL 10 should be used with caution in children and adolescents with high blood pressure (aged between 6-16 years) and not recommended for use in children under 6 years of age and those with kidney problems. However, consult your doctor before taking LISUPRIL 10.

Use in Geriatrics:

LISUPRIL 10 should be used with caution in elderly patients depending on their medical condition. Consult your doctor before taking LISUPRIL 10.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking LISUPRIL 10, inform your doctor, if you are taking any of the following medicine:

  • medicines used to treat heart failure (Ex. angiotensin II receptor blocker (ARBs) such as valsartan, telmisartan, irbesartan, aliskiren)
  • medicines that remove excess salt and water from the body (Ex. Diuretics such as amiloride, triamterene, spironolactone)
  • other medicines to help lower your blood pressure (Ex. Nitrates such as glyceryl trinitrate)
  • medicines containing potassium salt substitutes or drugs which can increase potassium in your body (Ex. antibiotics used in the treatment of bacterial infections such as co-trimoxazole also known as trimethoprim/sulfamethoxazole)
  • medicines used to treat certain depression and anxiety (Ex. lithium, amitriptyline, fluphenazine)
  • medicines that reduce pain and inflammation (Ex. non-steroidal anti-inflammatory drugs (NSAIDs) such as indomethacin, aspirin, celecoxib, rofecoxib)
  • medicines used to reduce joint pain and swelling (Ex. Injectable gold, sodium aurothiomalate, allopurinol)
  • medicine used in the treatment of diarrhoea (Ex. Enkephalinase inhibitor such as racecadotril)
  • medicines used in the treatment of diabetes (Ex. Insulin, gliclazide, metformin)
  • medicines that suppress your immune system (Ex. Immunosuppressants such as cyclosporin, sirolimus, everolimus)
  • medicines that break the blood clots formed in the body (Ex. Anticoagulants such as heparin, coumarin)
  • medicines that cause loss of sensation in the area given (Ex. Local anesthetics such as lidocaine)

Overdosage:

If you or anyone else accidentally takes more LISUPRIL 10, consult your doctor immediately or visit the nearby hospital. Symptom of overdose can be low blood pressure, shock (a dangerous decrease of blood pressure which, if untreated, may lead to collapse or loss of consciousness), difficulty breathing, increased or decreased heartbeat, dizziness, anxiety and cough.

SYNOPSIS

Drug :   Lisinopril
Pharmacological Category :   Angiotensin-Converting Enzyme (ACE) Inhibitor, Antihypertensive
Therapeutic Indication :   Heart failure (reduced ejection fraction), Hypertension
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep LISUPRIL 10 out of reach of children
  • Store in room temperature

FAQs ABOUT LISUPRIL 10

What will happen if I stop taking LISUPRIL 10?

Consult your doctor if you want to stop taking LISUPRIL 10. Suddenly stopping the medication may increase your blood pressure level. This can also increase your chances of having a heart attack or stroke. If you're disturbed by side effects of LISUPRIL 10, then your doctor may prescribe you a different medicine.

When will I feel better after taking LISUPRIL 10?

LISUPRIL 10 starts to work within a few hours after taking to reduce high blood pressure, but it may take a few weeks for it to take full effect. If you're taking it for heart failure, it may even take weeks or months. If you're taking it after a heart attack, you may not have any symptoms. In these cases, you may not feel any difference. This does not mean that the medicine is not working. It's important to keep taking LISUPRIL 10.

Will LISUPRIL 10 affect my contraception?

LISUPRIL 10 will not affect your contraception. But some types of methods of contraception, such as the combined pill and contraceptive patch, are not usually recommended if you have high blood pressure. Consult your doctor if you're taking or using a combined hormonal contraceptive.

Can I stop LISUPRIL 10 once my blood pressure is low?

Even if LISUPRIL 10 has lowered your blood pressure, it's best to continue with the medication. If you stop taking LISUPRIL 10, then your blood pressure could rise back up again. Blood pressure-lowering medicines will not cure high blood pressure, it will only control the blood pressure level. So, you need to take them for the rest of your life.

Will lifestyle changes help high blood pressure along with LISUPRIL 10?

While taking LISUPRIL 10, you can control your blood pressure and keep your heart healthy by making some key lifestyle changes such as quitting smoking, cutting down on alcohol intake, making exercise a regular habit and consuming a healthy diet with less salt intake. Apart from these changes, staying away from stress is also important for blood pressure and heart health.

REFERENCES

1. KD. Tripathi. Antihypertensive drugs. Essentials of medical pharmacology. Eighth edition. 2019. Page – 607.

2. Edgardo Olvera Lopez, Mayur Parmar, Venkata Satish Pendela, Jamie M. Terrell. Lisinopril. NIH National Library of Medicine, National center for biotechnology information. https://www.ncbi.nlm.nih.gov/books/NBK482230/

3. Krysiak, Robert, Marcin Basiak, and Boguslaw Okopien. Impact of lisinopril on cardiometabolic risk factors in men with hypertension and early-onset androgenetic alopecia: a pilot study. Journal of Cardiovascular Pharmacology [Revised in November 2021] [Accessed on 6th May 2022] https://www.ingentaconnect.com/content/wk/fjc/2021/00000078/00000005/art00014

4. Flaten HK, Sonn BJ, Saben JL, Shelton SK, Schwartz J, Ryall K, Monte AA. Genomic markers associated with successful treatment of hypertension with lisinopril: A pilot study. International Journal of Clinical Pharmacology and Therapeutics. [Revised in July 2021] [Accessed on 6th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383846/

5. Gerard Laboratories. Electronic Medicines Compendium (EMC). [Revised in November 2020] [Accessed on 6th May 2022] https://www.medicines.org.uk/emc/files/pil.10114.pdf

6. McDermott Laboratories Ltd. Health Products Regulatory Authority (HPRA) [Revised in September 2017] [Accessed on 6th May 2022] https://www.hpra.ie/img/uploaded/swedocuments/pil-21940224102017102914-636444377555156250.pdf

USEFUL DIAGNOSTIC TESTS

  • Kidney function test
  • Kidney ultrasound

PRODUCT DETAILS

    Country Of Origin
    India
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LISUPRIL 10 Tablet 15's

LISUPRIL 10 Tablet 15's Mkt: PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED

M.R.P.: Rs.135.00
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