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LEGEND 30mg Capsule 10's
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INTRODUCTION
LEGEND 30MG CAPSULE contains Lansoprazole which belongs to the group of medicines called Proton Pump Inhibitors. It is used in the treatment and prevention of intestinal and peptic (stomach) ulcers. Peptic or intestinal ulcers are open sores that form on the inside lining of your stomach and the upper part of your small intestine, causing stomach pain.
LEGEND 30MG CAPSULE is also used to treat reflux oesophagitis (inflammation of lower food pipe due to backflow of acidic stomach material) and Zollinger-Ellison Syndrome (small tumour in the first part of your bowel due to excessive gastrin secretion).
Before taking LEGEND 30MG CAPSULE, inform your doctor if you have severe liver disease, phenylketonuria, osteoporosis or if you are about to have a specific blood test (Chromogranin A). LEGEND 30MG CAPSULE should be used with caution in pregnant and breastfeeding women. LEGEND 30MG CAPSULE is not recommended for use in children.
Your doctor may perform an additional examination (endoscopy) to diagnose your condition or exclude malignant disease and regular blood tests to monitor your levels of magnesium. The most common side effects of taking LEGEND 30MG CAPSULE are dizziness, nausea, headache, diarrhea. Contact your doctor if any of the symptoms gets worse over time.
USES OF LEGEND 30MG CAPSULE
Treats:
- and prevents intestinal and peptic ulcers
- reflux oesophagitis
- Zollinger-Ellison Syndrome
HOW LEGEND 30MG CAPSULE WORKS
LEGEND 30MG CAPSULE suppresses stomach acid secretion by specific inhibition of an enzyme system at the secretory surface of stomach cells, that results in blockage of the final step of acid production.
DIRECTIONS FOR USE
Take LEGEND 30MG CAPSULE as advised by your physician. Swallow with enough water. Do not crush or chew it. For effective results take LEGEND 30MG CAPSULE at least half an hour before food. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking LEGEND 30MG CAPSULE unless your doctor advises you to stop.
SIDE EFFECTS OF LEGEND 30MG CAPSULE
COMMON
- headache, dizziness
- diarrhoea, constipation, stomach pain, nausea, vomiting, gas
- dry or sore mouth or throat
- skin rash, itching
- tiredness
- benign stomach polyps (pain on pressing the stomach, nausea, blood in stool, anemia)
- altered liver function tests
UNCOMMON
- depression
- joint or muscle pain
- swelling or fluid retention
- fracture of the back, wrist or hip
- altered blood cell counts
RARE
- fever
- restlessness, drowsiness, confusion, feeling things that are not really there, lack of sleep, visual disturbances, spinning sensation
- altered taste sensation, loss of appetite, inflammation of tongue
- skin reactions (burning or pricking feeling under the skin, bruising, reddening, excessive sweating)
- sensitivity to light
- hair loss
- tingling or prickling sensation, shakiness
- anaemia
- kidney problems
- pancreatitis (abdominal pain, nausea and vomiting)
- breast swelling in males, impotence
- candidiasis (fungal infection of skin or mucosa)
Stop taking LEGEND 30MG CAPSULE and contact your doctor immediately if you experience any of the following side effects:
- angioedema (swollen face, tongue or pharynx, difficulty to swallow or breathe, hives)
- severe hypersensitivity reactions including anaphylactic shock (fever, rash, swelling and sometimes a fall in blood pressure)
- very severe skin reactions causing reddening, blistering, inflammation and skin loss (Ex. Stevens Johnson Syndrome, toxic epidermal necrolysis, erythema multiforme)
- liver inflammation (yellowing of skin or eye)
HOW TO MANAGE SIDE EFFECTS
Diarrhoea:
To avoid dehydration, drink ample amount of fluids such as water, fruit juices or electrolytes. If symptom persists, contact your doctor.
Nausea or vomiting:
Take LEGEND 30MG CAPSULE with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If symptom persists, contact your doctor.
Headache:
Apply hot or cold-water bag on your head. Rest in a quiet and dark room. Massage the scalp or head gently. Avoid drinking excessive alcohol, as it could make your headache worse. If symptom persists, contact your doctor.
Dizziness:
Lie or sit down as soon as you start to feel dizzy. If you're having severe episode of spinning, lie in a dark and quite place and close your eyes. Try to avoid vehicle driving. If symptom persists, contact your doctor.
Skin rash:
Avoid hot showers as it can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors and moisturize your skin regularly. If symptom persists, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
LEGEND 30MG CAPSULE should be used with caution in pregnant women. Consult your doctor before taking it.
BREASTFEEDING
LEGEND 30MG CAPSULE should be used with caution in breastfeeding women. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you experience dizziness, spinning sensation, tiredness and visual disturbances after taking LEGEND 30MG CAPSULE.
KIDNEY
No dosage adjustment of LEGEND 30MG CAPSULE is necessary in patients with kidney impairment, however, consult your doctor before taking it.
LIVER
LEGEND 30MG CAPSULE should be used with caution in patients having severe liver disease. Consult your doctor before taking it.
ALLERGY
LEGEND 30MG CAPSULE is not recommended for use if you are allergic to Lansoprazole or any of the other ingredients of this medicine.
OTHERS
Before taking LEGEND 30MG CAPSULE, inform your doctor if you:
- have osteoporosis (weak and brittle bones)
- have low level of Vitamin B12
- are about to have a specific blood test (Chromogranin A)
- had a skin reaction when previously treated with any medicine used to reduce acidity
- have phenylketonuria (a rare genetic disorder)
Use in pediatrics:
LEGEND 30MG CAPSULE is not recommended for use in children. Consult your doctor before taking it.
Use in geriatrics:
No dosage adjustment of LEGEND 30MG CAPSULE is necessary in elderly patients, however, consult your doctor before taking it.
INTERACTIONS
A. Drug - Drug interactions:
Before taking LEGEND 30MG CAPSULE, inform your doctor if you are taking any of the following medicines:
- medicines used to treat HIV (Ex. atazanavir, nelfinavir)
- methotrexate (used in autoimmune disorders and cancer)
- medicines used to treat infections (Ex. ketoconazole, itraconazole, rifampicin)
- digoxin (used to treat heart problems)
- warfarin (used to stop blood clot formation)
- theophylline (used to treat asthma)
- tacrolimus (used to prevent transplant rejection)
- fluvoxamine, St John´s wort (used to treat depression and other psychiatric diseases)
- medicines used to treat heartburn or acid regurgitation (Ex. magnesium hydroxide, calcium carbonate)
Overdosage:
If you or anyone else accidentally take too much of LEGEND 30MG CAPSULE, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Lansoprazole |
| Pharmacological Category | : | Proton Pump Inhibitors |
| Therapeutic Indication | : | Reflux oesophagitis, Stomach ulcers, Zollinger-Ellison Syndrome |
| Dosage Forms | : | Injection, Capsule, Tablet, Orally Disintegrating Tablet |
MORE INFORMATION
- Keep LEGEND 30MG CAPSULE out of reach of children
- Store below 25°C
FAQs ABOUT LEGEND 30MG CAPSULE
Does LEGEND 30MG CAPSULE reduce heartburn?
LEGEND 30MG CAPSULE stops the acid secretion in stomach and prevents the movement of contents from stomach back up to the food pipe and thus reduces heartburn (burning pain and discomfort felt in the chest and throat).
What is the preferred time to take LEGEND 30MG CAPSULE?
LEGEND 30MG CAPSULE works best if taken on an empty stomach at least 30 minutes before food to reduce the amount of acid secretion. Your doctor will decide the correct dose and duration of LEGEND 30MG CAPSULE treatment for you depending upon your age, body weight and disease condition.
Can I take LEGEND 30MG CAPSULE along with painkillers?
Yes. LEGEND 30MG CAPSULE can be taken with painkillers because some of the painkillers like aspirin, ibuprofen cause acidity in some patients. LEGEND 30MG CAPSULE reduces the acidity caused by the painkillers. Talk to your doctor for advice.
Does LEGEND 30MG CAPSULE cause dry mouth?
One of the common side effects of LEGEND 30MG CAPSULE is dry or sore mouth. In such case, chew sugar-free gum or suck on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use alcoholic mouthwashes because they can be drying. If symptom persists, consult your doctor.
What if I forget a dose of LEGEND 30MG CAPSULE?
If you forget to take a dose of LEGEND 30MG CAPSULE, take it as soon as you remember. However, skip that dose if it's almost time for the next dose. Do not take LEGEND 30MG CAPSULE two times to make up for the missed dose.
REFERENCES
1. KD. Tripathi. Drugs for Peptic Ulcer and Gastroesophageal Reflux Disease. Essentials of Medical Pharmacology. Eighth edition. Page- 701.
2. Thomas O. Kovacs, James W. Freston, Marian M. Haber, Barbara Hunt, Stuart Atkinson and David A. Peura. Long-Term Efficacy of Lansoprazole in Preventing Relapse of Erosive Reflux Esophagitis. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. August 2009. [Accessed 21st May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2702676/
3. Takeda. Safety and Efficacy of Lansoprazole in Patients With Reflux Disease. NIH U.S. National Library of Medicine. ClinicalTrials.gov. [Revised in September 2012] [Accessed 21st May 2022] https://clinicaltrials.gov/ct2/show/NCT01135368
4. LABORATORIOS LICONSA, S.A. Electronic Medicines Compendium (EMC). [Revised in September 2021]. [Accessed 21st May 2022] https://www.medicines.org.uk/emc/files/pil.4761.pdf
5. Takeda Pharmaceuticals America, Inc. U.S Food & Drug Administration [Revised in September 2012] [Accessed 21st May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020406s078-021428s025lbl.pdf
6. Central Drugs Standard Control Organization (CDSCO). [Accessed 21st May 2022] https://cdscoonline.gov.in/CDSCO/Drugs
USEFUL DIAGNOSTIC TESTS
- Urea breath test
- Upper GI endoscopy
AUTHOR DETAILS
Written By Dr. Jeenal Rajani, Pharm.D.
Last updated on 22 Nov 2022 | 05:56 PM(IST)
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.