KETOCIP contains Ketoconazole belongs to the class of drugs called azole antifungals. It is used to treat fungal infections including blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. It gets bound to proteins such as albumin in the circulating blood and is widely distributed in body tissues. This medicine works by binding to the fungal p450 enzymes and stops the cells making ergosterol of the cell wall which is necessary for them to grow.
Always take this medicine as directed by physician. Your doctor will decide the dose and duration of therapy depending upon your age, weight and condition. Swallow the medicine with a glass of water. It is recommended for the use in children and adolescents. Do not take this medicine, if you have adrenal insufficiency. It is not recommended for use in pregnant or breastfeeding women. Consult your doctor before taking this medicine. Tell your doctor, if you are taking or taken or might take any other medicines. The most common side effects include diarrhea, nausea, headache, stomach pain and abnormal liver function test.
KETOCIP binds to the fungal p450 enzymes and stops the cells making ergosterol of the cell wall which is necessary for them to grow.
Always take KETOCIP exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water. If you take more this medicine than you should, talk to your doctor.
Skin rash:
Avoid bath in hot water because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.
Nausea and vomiting:
Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Diarrhea:
Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicine without consulting your doctor.
KETOCIP is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
KETOCIP is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
Do not drive or operate any machinery while taking this medicine, it may make you feel dizzy.
Consumption of alcohol is not recommended during treatment with KETOCIP.
KETOCIP should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
KETOCIP should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
Do not take if you are allergic to this medicine.
If you have any heart related problems, consult your doctor for advice before taking this medicine.
Talk to your doctor, if you are taking:
Drug | : | Ketoconazole |
Pharmacological Category | : | Antifungal |
Therapeutic Indication | : | Treat fungal infection |
Dosage Forms | : | Tablet, Cream, Gel, Ointment, Lotion, Soap, Dusting powder |
Store at room temperature 15-25°C and keep out of reach of children.
Can KETOCIP be used in pregnant women?
No. It is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
How does KETOCIP kill fungus?
It kills fungi by binding to the fungal p450 enzymes and stops the cells making ergosterol of the cell wall.
1. Hadeer Sinawe; Damian Casadesus, Ketoconazole, [Revised on Jun 2020] [Accessed 11 Dec 2020] https://www.ncbi.nlm.nih.gov/books/NBK559221/
2. Jan van cutsem; The antifungal activity of ketoconazole; [Revised on Jan 1983] [Accessed 11 Dec 2020] https://www.amjmed.com/article/0002-9343(83)90508-9/fulltext
3. K.D.Tripathi, Essentials of medical pharmacology, Antimicrobial drugs, Chapter 57 – Antifungal drugs, 7th edition 2013, Page – 792.
4. Glenmark Pharmaceuticals s.r.o., U.S. Food and Drug Administration; [Revised on July 2013] [Accessed 11 Dec 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/018533s040lbl.pdf
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