INTRODUCTION

KALZIN NANO ORAL SOLUTION contains Cholecalciferol which belongs to the group of medicines called Vitamin D analogs. It is used to treat and prevent Vitamin D deficiency. This may occur when your diet or lifestyle does not provide you enough vitamin D or when your body requires more vitamin D during pregnancy.

Along with this treatment, your doctor might advise you to eat and drink foods that are rich in calcium. Your doctor might want to take certain blood tests prior to the treatment to understand the existing condition.

KALZIN NANO ORAL SOLUTION is not recommended for use if you have high blood or urine levels of calcium, kidney stones or serious kidney problems and high levels of Vitamin D.

Before taking KALZIN NANO ORAL SOLUTION, inform your doctor if you have heart or kidney disease, sarcoidosis (a multisystem chronic inflammatory condition which can affect your lungs, heart, and kidneys) or if you are taking medicines containing vitamin D, increase parathyroid hormone in your blood or rickets (problems in bone).

KALZIN NANO ORAL SOLUTION should be used with caution in pregnant and breastfeeding women. KALZIN NANO ORAL SOLUTION is not recommended for use in children and adolescents (below 12 years of age). It should be used with caution in elderly patients.

The most common side effects of taking KALZIN NANO ORAL SOLUTION are increased calcium level in the blood or urine. Consult your doctor if you experience any unusual effects.

USES OF KALZIN NANO ORAL SOLUTION

• To prevent or treat vitamin D deficiency (in adults, elderly and children over 12 years of age)

HOW KALZIN NANO ORAL SOLUTION WORKS

KALZIN NANO ORAL SOLUTION helps the body to absorb calcium and phosphorus by increasing their absorption from the gut and reducing the amount removed by the kidneys and it is a fat-soluble vitamin.

DIRECTIONS FOR USE

Take KALZIN NANO ORAL SOLUTION as advised by your physician.  Shake well before use. You may also mix the dose with a small amount of cold or lukewarm food immediately before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF KALZIN NANO ORAL SOLUTION

HOW TO MANAGE SIDE EFFECTS

Skin Rash Or Itching

Do not scratch the affected area. Wear protective clothing while going outdoors. Regularly moisturize your skin. Consult your doctor if the symptoms worsen.

WARNING & PRECAUTIONS

PREGNANCY

Use with Caution

KALZIN NANO ORAL SOLUTION should be used with caution in pregnant women or women planning to have a baby. Dose will be adjusted by your doctor. Consult your doctor before taking it.

BREASTFEEDING

Use with Caution

KALZIN NANO ORAL SOLUTION should be used with caution in breastfeeding women as it passes through the breast milk. Dose will be adjusted by your doctor. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Safe

KALZIN NANO ORAL SOLUTION does not affect your ability to drive or use machines. Consult your doctor before taking it.

KIDNEY

Consult your doctor

KALZIN NANO ORAL SOLUTION is not recommended for use if you have severe kidney problems or kidney stones. It should be used with caution in patients with kidney disease or damage. Consult your doctor before taking KALZIN NANO ORAL SOLUTION. 

ALLERGY

Contraindicated

Do not take KALZIN NANO ORAL SOLUTION if you are allergic to cholecalciferol, nuts or any other ingredients of this medicine.

HEART DISEASE

Use with Caution

KALZIN NANO ORAL SOLUTION should be used with caution in patients with heart disease. Consult your doctor before taking KALZIN NANO ORAL SOLUTION.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking KALZIN NANO ORAL SOLUTION, inform your doctor, if you are taking any of the following medicines:

• medicines used to treat epilepsy (Ex. carbamazepine, phenobarbital, phenytoin)
• cardiac glycosides to treat heart condition (Ex. digoxin, digitoxin)
• thiazide diuretics (water tablets) (Ex. bendroflumethiazide) to treat high blood pressure
• medicine used to treat high cholesterol (Ex. cholestyramine)
• laxative containing liquid paraffin to treat constipation
• medicines used to treat fungal infections (Ex. ketoconazole, itraconazole)
• actinomycin (medicine used to treat some forms of cancer)
• glucocorticosteroids (Ex. dexamethasone or prednisolone) used to treat inflammation

Overdosage:

If you or anyone else accidentally takes too much of KALZIN NANO ORAL SOLUTION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include damage of soft tissues and kidney, lack of appetite, thirst, nausea, vomiting, constipation, abdominal pain, muscle weakness, fatigue, mental disturbances, increased urination, bone pain and in severe cases may result in coma and death.

SYNOPSIS

MORE INFORMATION

• Keep the medicine out of reach of children
• Store KALZIN NANO ORAL SOLUTION at room temperature

FAQs ABOUT KALZIN NANO ORAL SOLUTION

Q: What is KALZIN NANO ORAL SOLUTION used for?

A: KALZIN NANO ORAL SOLUTION is used to prevent or treat vitamin D deficiency (which may occur when your diet or lifestyle does not provide you enough vitamin D or when your body requires more vitamin D during pregnancy).

Q: For how long should I take KALZIN NANO ORAL SOLUTION?

A: Your doctor might advise you on how long you should continue to take KALZIN NANO ORAL SOLUTION. You will need to consult your doctor from time to time to review your treatment and assess your symptoms.

Q: What happens if you take more KALZIN NANO ORAL SOLUTION than your required dose?

A: If you or anyone else accidentally takes too much of KALZIN NANO ORAL SOLUTION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include lack of appetite, thirst, nausea, vomiting, constipation, abdominal pain, muscle weakness, fatigue, mental disturbances, increased urination, bone pain and in severe cases may result in coma and death.

Q: How does KALZIN NANO ORAL SOLUTION work?

A: KALZIN NANO ORAL SOLUTION helps the body to absorb calcium and phosphorus and is a fat-soluble vitamin. It is produced naturally by your skin after exposure to the sun and is also found in some foods. KALZIN NANO ORAL SOLUTION is prescribed as a dietary supplement when there is a deficiency of Vitamin D.

Q: Is KALZIN NANO ORAL SOLUTION safe to use in patients with kidney disease?

A: KALZIN NANO ORAL SOLUTION is not recommended for use if you have severe kidney problems or kidney stones. It should be used with caution in patients with kidney disease or damage. Consult your doctor before taking KALZIN NANO ORAL SOLUTION.  

REFERENCES

1. KD. Tripathi. Section 11, Vitamins. Essentials of medical pharmacology. Seventh edition. 2013. Page – 909.

2. Jose-Luis Perez-Castrillon, Ricardo Usategui-MartinandPawel Pludowski Treatment of Vitamin D Deficiency with Calcifediol: Efficacy and Safety Profile and Predictability of Efficacy. May 2022. [Accessed on 21st June 2022] https://www.mdpi.com/2072-6643/14/9/1943/html

3. J Christopher Gallagher, Daniel D Bikle. Vitamin D: Mechanisms of Action and Clinical Applications. National library of Medicine, National center for Biotechnology information. Pubmed.gov 2017. [Accessed on 21st June 2022] Vitamin D: Mechanisms of Action and Clinical Applications - PubMed (nih.gov)

4. Thame Laboratories. Electronic Medicine Compendium. [Revised in September 2019] [Accessed on 21st June 2022] https://www.medicines.org.uk/emc/files/pil.8091.pdf

5. Ciplamed. Dsol sachet. (Cholecalciferol drops 400IU) [Revised in May 2016] [ Accessed on 21st June 2022] https://www.ciplamed.com/content/d-sol-granules-chewable-tablets-drops

6. SMB Technology S.A. Health products regulatory authority (HPRA). [Revised in March 2017] [Accessed on 21st June 2022] https://www.hpra.ie/img/uploaded/swedocuments/PIL-2185233-11052017115218-636301003399375000.pdf 

USEFUL DIAGNOSTIC TESTS

• Vitamin D3 test

AUTHOR DETAILS

Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 28 Jan 2023 | 12:59 PM(IST)