JAKAVI 15MG contains Ruxolitinib which belongs to a group of medicines called kinase inhibitors. It is indicated to treat enlarged spleen or with symptoms related to myelofibrosis (a rare form of blood cancer). It is also used to control the haematocrit (the amount of red blood cells in the blood) in patients with polycythemia vera.
Ruxolitinib is a selective inhibitor of the Janus Kinases which blocks the action of certain enzymes and reduces the size of the spleen in patients with myelofibrosis and helps to reduce the risk of serious blood or vascular complications. This medicine also reduces the amount of red blood cells in the blood in patients with polycythemia vera.
Before taking JAKAVI 15MG, tell your physician if you have liver, kidney or heart problems, are pregnant or breastfeeding. This medicine is not suitable for use in children and adolescents below 18 years of age. The common side effects are headache, dizziness and infections.
Ruxolitinib is a kinase inhibitor that works at reducing spleen size and or its associated symptoms caused by myelofibrosis.
Always take JAKAVI 15MG as instructed by your doctor. Swallow whole and do not crush or chew. It can be taken with or without food.
Headache:
Rest and drink plenty of fluids. Apply a wet or cold cloth to forehead and rest in a quiet, comfortable, dark room.
Dizziness:
Get up and move around to feel awake and eat a healthy food to boost your energy.
JAKAVI 15MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
JAKAVI 15MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
Do not drive or handle any tools while taking this medicine since it may cause dizziness.
JAKAVI 15MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
JAKAVI 15MG should be used with caution in patients suffering from liver function impairment, active liver diseases or viral hepatitis B. Consult your doctor for advice.
Tell your doctor if you are allergic (hypersensitive) to Ruxolitinib.
JAKAVI 15MG should be used with caution in patients suffering from active heart diseases or low heart rate. Consult your doctor for advice.
Tell your doctor before taking this medicine if you have or had:
Tell your doctor if you are taking,
Drug | : | Ruxolitinib |
Pharmacological Category | : | Antineoplastic Agent, Tyrosine kinase inhibitor |
Therapeutic Indication | : | Myelofibrosis, Polycythemia vera |
Dosage Forms | : | Tablet |
Store below 20-25°C and keep out of reach of children.
Does JAKAVI 15MG cause fatigue?
It may cause fatigue due to anemia (low red blood cell counts). If this persists for a long time, consult your doctor for advice.
How long does it take for JAKAVI 15MG to work?
It usually takes 6 months to see if the medicine is working for you. Consult your doctor for advice.
Does JAKAVI 15MG safe while driving?
Do not drive or handle any machines since it may cause dizziness.
1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 1240.
2. Claire Harrison and Alessandro M. Vannucchi. Ruxolitinib: a potent and selective Janus kinase 1 and 2 inhibitor in patients with myelofibrosis. An update for clinicians. Dec, 2012. [Accessed on June 12, 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627327/s
3. Novartis Pharmaceuticals Canada Inc. June 15, 2012. [Revised on Nov 26, 2020] [Accessed on June 12, 2021] PrJAKAVI® - Novartishttps://www.novartis.ca › files › jakavi_scrip_e
4. Novartis Pharmaceuticals UK Ltd. Electronic Medicines Compendium (EMC). [Revised on Dec, 2020] [Accessed on June 12, 2021] https://www.medicines.org.uk/emc/files/pil.7786.pdf
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.