IVADIN XR 10 Tablet 10's

Angina Rx required

Best Price* ₹ 280.00 MRP ₹ 350.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Zuventus Healthcare Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

IVADIN XR 10 TABLET contains Ivabradine which belongs to the group of medicines called Hyperpolarization-activated cyclic nucleotide-gated channel blockers. IVADIN XR 10 TABLET is used to treat symptomatic stable angina pectoris (chest pain) in adult patients who are intolerant/incapable to take heart medicines (such as beta blockers) and whose heart rate is over/equal to 70 beats per minute.

It is also used to treat chronic heart failure in adult patients whose heart rate is over/equal to 75 beats per minute which are used as a combination therapy with beta-blockers or in adult patients who are contraindicated to use beta blockers.

IVADIN XR 10 TABLET is not recommended for use in patients allergic to ivabradine. It is also not recommended for use in patients suffering from very low blood pressure, heart problems (such as unstable angina, cardiogenic shock), severe kidney disease, and/or severe liver disease.

Before taking IVADIN XR 10 TABLET, inform your doctor if you have mild to moderate low blood pressure, chronic eye retinal disease, recent stroke (cerebral attack), heart rhythm disorders (such as irregular heartbeat, palpitation, increase in chest pain), and/or moderate liver disease.

IVADIN XR 10 TABLET is generally not recommended for use in pregnant and breast-feeding women which is also not recommended for use in children and adolescents (aged below 18 years). The medicine is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.

The most common side effects of taking IVADIN XR 10 TABLET are brief moments of increased brightness (due to sudden changes in light intensity), slow heart rate, uncontrolled blood pressure, headache, dizziness, and/or blurred vision. Consult your doctor if any of these symptoms worsen.

USES OF IVADIN XR 10 TABLET

  • Symptomatic stable angina pectoris (chest pain) in adult patients (with heart rate above/equal to 70 beats/minute)
  • Chronic heart failure in adult patients (with heart rate above/equal to 75 beats/minute)

HOW IVADIN XR 10 TABLET WORKS

IVADIN XR 10 TABLET works by reducing the heart rate which leads to low oxygen requirement of the heart resulting in improved blood supply throughout the body (with each hear beat) thus providing relief from angina pectoris and preventing the occurrence of chronic heart failure in affected individuals

DIRECTIONS FOR USE

Tablet:

Take IVADIN XR 10 TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your physician will decide the correct dose and duration for you depending on your age, body weight and disease condition.

Orally Disintegrating Tablet:

Take IVADIN XR 10 TABLET as advised by your physician. Place IVADIN XR 10 TABLET inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine.. Your physician will decide the correct dose and duration for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF IVADIN XR 10 TABLET

COMMON

  • brief moments of increased brightness (due to sudden changes in light intensity)
  • slow heart rate
  • signs of atrial fibrillation (irregular rapid contraction of heart) such as chest pain, pounding heartbeat, tiredness
  • uncontrolled blood pressure
  • headache, dizziness, blurred vision

UNCOMMON

  • racing heartbeat
  • nausea, constipation, diarrhoea, abdominal pain
  • sudden internal/external spinning sensation
  • difficulty breathing
  • muscle spasms
  • skin rash
  • signs of angioedema such as the swollen face, tongue/throat, difficulty in breathing/swallowing
  • low blood pressure, fainting, tiredness, weakness
  • double vision, impaired vision

RARE

  • red itchy welts, itching, skin reddening
  • feeling unwell

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes and apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if the symptom does not improve.

Dizziness:

Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.

Nausea:

Try to take IVADIN XR 10 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.

Constipation:

Try to eat high-fibre foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor to receive alternate treatments for constipation.

Diarrhoea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhoea. Consult your doctor and inform them if the symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

IVADIN XR 10 TABLET is not recommended for use during pregnancy and in women planning for pregnancy. Women of childbearing potential should use reliable contraceptive measures while taking IVADIN XR 10 TABLET. Consult your doctor before taking the medicine.

BREASTFEEDING

IVADIN XR 10 TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking the medicine.

DRIVING AND USING MACHINES

Do not drive or operate any machines after taking IVADIN XR 10 TABLET since it may cause temporary blindness (due to sudden changes in light intensity) which may after your ability to concentrate while driving or operating machines.

KIDNEY

IVADIN XR 10 TABLET should be used with caution in patients with severe kidney disease. Consult your doctor before taking the medicine.

LIVER

IVADIN XR 10 TABLET is not recommended for use in patients with severe liver disease. It should be used with caution in patients with moderate liver disease. Consult your doctor before taking the medicine.

ALLERGY

Do not take IVADIN XR 10 TABLET if you are allergic to ivabradine, and/or any other ingredients of this medicine.

HEART DISEASE

IVADIN XR 10 TABLET is not recommended for use in patients with heart problems such as slow resting heart rate (beats below 70/minute), cardiogenic shock, heart rhythm disorders (such as sick sinus syndrome, sino-atrial block, heart block), heavy heart attack, and/or severe heart failure. It should be used with caution in patients with other heart rhythm disorders (such as irregular heartbeat, palpitation, increase in chest pain), sustained atrial fibrillation, long QT syndrome, slow heartbeat (associated with signs such as tiredness, dizziness, shortness of breath), and/or bundle branch block (type of severe heart failure). Consult your doctor before taking the medicine.

OTHERS

IVADIN XR 10 TABLET is not recommended for use if you:

  • suffer from very low blood pressure
  • have unstable angina (a severe form of chest pain)

Before taking IVADIN XR 10 TABLET, inform your doctor if you:

  • had a recent stroke (cerebral attack)
  • suffer from mild to moderate low blood pressure (after change in antihypertensive treatment)
  • have chronic eye retinal disease

Use in Paediatrics:

IVADIN XR 10 TABLET is generally not recommended for use in children and adolescents (aged below 18 years). Consult your doctor before taking the medicine.

Use in Geriatrics:

IVADIN XR 10 TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking the medicine.

INTERACTIONS

A.Drug - Drug interactions:

Before taking IVADIN XR 10 TABLET, inform your doctor if you are taking any of the following medicine:

  • medicines used to treat fungal infections (Ex. fluconazole, ketoconazole, itraconazole)
  • rifampicin (medicine used to treat tuberculosis)
  • barbiturates (medicines used for difficulty sleeping or epilepsy)
  • phenytoin (used for epilepsy)
  • hypericum perforatum/St John’s Wort (herbal medicines used for depression)
  • medicines used to treat heart rhythm disorders (Ex. quinidine, disopyramide, sotalol, ibutilide, amiodarone)
  • bepridil (medicine used to treat angina pectoris)
  • medicines to treat anxiety, schizophrenia or other psychoses (Ex. pimozide, ziprasidone, sertindole)
  • medicines used to treat malaria (Ex. mefloquine,halofantrine)
  • intravenous erythromycin (medicine used to treat bacterial infections in different parts of the body)
  • pentamidine (medicine used in the management and treatment of pneumocystis pneumonia, leishmaniasis, trypanosomiasis)
  • cisapride (used for acid reflux)
  • diuretics (medicines used to treat oedema, high blood pressure) Ex. furosemide, hydrochlorothiazide, indapamide
  • clarithromycin, josamycin, telithromycin,erythromycin (medicines used for bacterial infections)
  • nelfinavir, ritonavir (medicines used to treat HIV infections)
  • nefazodone (medicine used to treat depression)
  • diltiazem, verapamil (medicines used to treat high blood pressure/angina pectoris)

B.Drug -Food interaction:

Avoid drinking grapefruit juice while taking IVADIN XR 10 TABLET as it may alter the effect of the medicine.

Overdosage:

If you or anyone else accidentally take too much of IVADIN XR 10 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are breathlessness and tiredness.

SYNOPSIS

Drug :   Ivabradine
Pharmacological Category :   Hyperpolarization-activated cyclic nucleotide-gated channel blockers 
Therapeutic Indication :   Symptomatic stable angina, Chronic Heart failure       
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep IVADIN XR 10 TABLET out of the sight and reach of children
  • Store at room temperature

REFERENCES

1. K.D.Tripathi. Antianginal and Other Anti-ischaemic Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 554.

2. Mirembe Reed; Connor C. Kerndt; Diala Nicolas. Ivabradine. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. [Revised in May 2022] [Accessed on 14th May 2022] https://www.ncbi.nlm.nih.gov/books/NBK507783/

3. Lupin Limited. IVABRAD OD 10MG, IVABRAD OD 15MG. [Accessed on 14th May 2022] https://www.lupin.com/our-products/product-finder/?searchkey=Ivabradine

4. Alniche Life Sciences Pvt. Ltd. Ivaniche. [Accessed on 14th May 2022] https://www.alniche.com/cardiac-diabetes-care/

5. Noucor Health S.A. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 14th May 2022] https://www.medicines.org.uk/emc/files/pil.9104.pdf

USEFUL DIAGNOSTIC TESTS

  • Electrocardiogram
  • Stress test
  • Coronary angiography

VIDEOS

Ivabradine Tablet - Drug Information

Ivabradine Tablet : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage

PRODUCT DETAILS

    Net Qty
    1 N
    Hsn Code
    30049099
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