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INTRODUCTION
ITIN 12MG TABLET contains Ivermectin which belongs to the group of medicines called Antiparasitic agents. It is used to treat parasitic infections like intestinal strongyloidiasis (infection in gut caused by a type of round worm called strongyloides stercoralis), infection caused by Wuchereria bancrofti in blood and tissues and human scabies (infectious disease of the skin) after previous treatment has failed. It is also used for the treatment of Onchocerciasis (known as river blindness, parasitic disease caused by Onchocerca volvulus).
Before taking ITIN 12MG TABLET, inform your doctor if you have a condition called loa loa (eye infection) or have a weak immune system and taking any other medicines for other conditions.
ITIN 12MG TABLET is not recommended for use in pregnant and breastfeeding women unless advised by the doctor. Contact your doctor before taking this medicine.
The safety and effectiveness of ITIN 12MG TABLET in children weighing less than 15 kg has not been evaluated. ITIN 12MG TABLET should be used with caution in elderly patients (aged 65 years and above).
The most common side effects of taking ITIN 12MG TABLET are diarrhea, nausea, dizziness, itching and fast heart rate. Consult your doctor if any of the side effects worsen.
USES OF ITIN 12MG TABLET
It is used to treat:
- intestinal strongyloidiasis
- parasitic infection caused by Wuchereria bancrofti in blood and tissues
- human scabies after previous treatment has failed
- onchocerciasis (river blindness)
HOW ITIN 12MG TABLET WORKS
ITIN 12MG TABLET works by binding to the nerve and muscle cells of parasites leading to their death, thus helps to treat various parasitic infections.
DIRECTIONS FOR USE
Take ITIN 12MG TABLET as advised by your physician.
For Tablet: Swallow ITIN 12MG TABLET with a glass of water. Do not crush or chew the medicine. But in children younger than 6 years, the medicine should be crushed before swallowing.
For Dispersible Tablet: Disperse ITIN 12MG TABLET in the specified quantity of water as advised by your doctor. Consume the mixture immediately after reconstitution.
Dose and duration will be decided by your doctor depending upon your age, body weight and disease condition.
SIDE EFFECTS OF ITIN 12MG TABLET
COMMON
- diarrhea
- nausea
- dizziness
- joint pain, synovitis
- axillary lymph, inguinal or cervical lymph node enlargement and tenderness
- itching
- edema, facial and peripheral edema
- papular and pustular or frank urticarial rash
- fever
- inflammation of the corneal limbus
- fast heart rate
- low blood pressure when standing up from sitting or lying position (orthostatic hypotension)
UNCOMMON
- abnormal physical weakness
- stomach pain
- sleepiness, vertigo (spinning sensation of the head)
- shakiness
- rash, urticaria
- headache, muscle pain
RARE
Stop taking ITIN 12MG TABLET and contact your physician immediately if you experience any of the following side effects:
- allergic reaction (such as rash, hives, itching, sudden fever and difficulty breathing)
HOW TO MANAGE SIDE EFFECTS
Headache:
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Diarrhea:
Drink lot of fluids such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.
Stomach pain:
Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve on its own.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume alcohol as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
WARNING & PRECAUTIONS
PREGNANCY
ITIN 12MG TABLET is not recommended for use during pregnancy unless it is considered clearly necessary. Contact your doctor before taking ITIN 12MG TABLET.
BREASTFEEDING
ITIN 12MG TABLET is not recommended for use in breastfeeding women unless it is considered clearly necessary. Contact your doctor before taking ITIN 12MG TABLET.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizziness, drowsiness or feeling shaky or spinning sensation after taking ITIN 12MG TABLET.
ALLERGY
Do not take ITIN 12MG TABLET if you are allergic to Ivermectin or any other ingredients of this medicine. It should be used with caution in patients with other substances such as foods, preservatives or dyes.
OTHERS
Before taking ITIN 12MG TABLET, inform your doctor if you have:
- a condition called loa loa (eye infection)
- a weak immune system (immunity disorder)
Use in pediatrics:
The safety and effectiveness of ITIN 12MG TABLET in children weighing less than 15 kg has not been evaluated. In children under 6 years of age, the medicine should be crushed before swallowing. Consult your child doctor for advice.
Use in geriatrics:
ITIN 12MG TABLET should be used with caution in elderly patients (aged 65 years and above). Contact your doctor before taking ITIN 12MG TABLET.
INTERACTIONS
A. Drug - Drug interactions:
Before taking ITIN 12MG TABLET, inform your doctor if you are taking any of the following medicines:
- diethylcarbamazine citrate (DEC) (used to treat lymphatic filariasis)
- warfarin (used to prevent blood clots)
B. Drug – Food interactions:
Do not take food 2 hours before or two hours after taking ITIN 12MG TABLET.
Overdosage:
If you or anyone else accidentally take too much of ITIN 12MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include rash, urticaria, contact dermatitis, oedema, headache, dizziness, abnormal physical weakness, nausea, vomiting, abdominal pain, diarrhea, fits, impaired coordination, breathing difficulty, tingling or prickling sensation in the arms, hands, legs or feet, decreased alertness, sleepiness or drowsiness, altered consciousness, coma, confusion, disorientation and death.
SYNOPSIS
| Drug | : | Ivermectin |
| Pharmacological Category | : | Anthelmintics |
| Therapeutic Indication | : | Parasitic infections |
| Dosage Forms | : | Tablet, Dispersible tablet, Lotion, Cream, Shampoo, Soap |
MORE INFORMATION
- Keep ITIN 12MG TABLET out of reach of children
- Store ITIN 12MG TABLET below 30°C
FAQs ABOUT ITIN 12MG TABLET
What is ITIN 12MG TABLET used for?
ITIN 12MG TABLET is used to treat parasitic infections like intestinal strongyloidiasis (infection in gut caused by a type of round worm called strongyloides stercoralis), infection caused by Wuchereria bancrofti in blood and tissues and human scabies (infectious disease of the skin) after previous treatment has failed. It is also used for the treatment of Onchocerciasis (known as river blindness, parasitic disease caused by Onchocerca volvulus).
Is ITIN 12MG TABLET safe during pregnancy?
ITIN 12MG TABLET is not recommended for use during pregnancy unless it is clearly advised by the doctor. Contact your doctor before taking ITIN 12MG TABLET if you are pregnant or planning to get pregnant.
Can ITIN 12MG TABLET be used in children?
The safety and effectiveness of ITIN 12MG TABLET in children weighing less than 15 kg has not been evaluated. Your child’s doctor may prescribe safer alternative for your child to treat the specific infection.
What precautions do I need to follow while taking ITIN 12MG TABLET?
Before taking ITIN 12MG TABLET, inform your doctor if you have a condition called loa loa (eye infection), weak immune system or any allergies to any other medicines or any other substances such as foods, preservatives or dyes.
Can I drive or operate any machines after taking ITIN 12MG TABLET?
Do not drive or operate any machines if you feel dizziness, drowsiness or feeling shaky or spinning sensation after taking ITIN 12MG TABLET. Contact your doctor before taking ITIN 12MG TABLET.
REFERENCES
1. KD Tripathi. Antimicrobial Drugs. Essentials of Medical Pharmacology. 7th edition. 2013. Page- 854.
2. Roz Lainng, Victoria Gillan, Eileen Devaney. Ivermectin- Old Drug, New Tricks. Trends in Parasitology. June 2017. [Accessed on 10th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446326/
3. Merck Sharp & Dohme Limited. New Zealand Customer Medicine Information. [Revised in May 2021] [Accessed on 10th October 2022] https://www.medsafe.govt.nz/consumers/cmi/s/stromectol.pdf
4. Substipharm Development. Ivermectin. [Accessed on 10th October 2022] https://www.ncl-mon.nhs.uk/wp-content/uploads/Guidelines/5_Ivermectin_PIL.PDF
5. Merck Sharp & Dohme BV. Ivermectin. [Revised in September 2015] [Accessed on 10th October 2022] https://www.isglobal.org/documents/10179/7648746/Ivermectine_LabelEuropa_150903_Stromectol_PIL_EN_II019_NETHERLANDS.pdf/f654dd0a-009d-4d62-8c95-183e533f2fd2
6. Merck Sharp & Dohme BV. Ivermectin. [Revised in May 2022] [Accessed on 10th October 2022] https://www.merck.com/product/usa/pi_circulars/s/stromectol/stromectol_pi.pdf
7. Merck Sharp & Dohme Corp. Ivermectin. [Revised in September 2018] [Accessed on 10th October 2022] https://pdf.hres.ca/dpd_pm/00047237.PDF
8. Iverhope 6mg, 12mg (Ivermectin). [Accessed on 10th October 2022] https://www.macleodspharma.com/products/
USEFUL DIAGNOSTIC TESTS
- Complete blood count
- Liver function test
- Stool examination
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