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Intalith CR 450mg Tablet 10'S

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Depression Rx required
Lithium Carbonate 450 mg
MRP ₹39.50
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*10 Tablet(s) in a Strip * Mkt: Intas Pharmaceuticals Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout
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INTRODUCTION

INTALITH CR 450MG TABLET contains Lithium which belongs to the group of medicines called Anti-manic agents. It is used in the treatment of anti-depression. INTALITH CR 450MG TABLET also used to manage or control hypomania (less severe form of mania) and aggressive or self-harming behaviour.

Depression (major depressive disorder) is a common and serious medical illness that negatively affects how you feel, the way you think and how you act. It causes feelings of sadness and/or a loss of interest in activities you once enjoyed. It can lead to a variety of emotional and physical problems and can decrease your ability to function at work and at home.

Prior to INTALITH CR 450MG TABLET treatment, your doctor may check on your kidneys, thyroid and heart to avoid any untoward side effects. INTALITH CR 450MG TABLET is not recommended for use in patients having kidney, thyroid and heart problems, or if you have Addison’s disease.

Before taking INTALITH CR 450MG TABLET, inform your doctor if you have epilepsy, persistent headaches, cold or flu, gastroenteritis, or if you had or are about to have any weight loss surgery.INTALITH CR 450MG TABLET is not suitable for use in pregnant or breastfeeding women. Consult your doctor before taking the medicine.

INTALITH CR 450MG TABLET is not recommended for use in children. Consult your child’s doctor for advice. INTALITH CR 450MG TABLET should be used with caution in patients above 65 years of age. The most common side effects of taking INTALITH CR 450MG TABLET are hand trembling, excessive urination, increased thirst, nausea, and general discomfort during beginning of the treatment. Contact your doctor if the side effects persists for a long time.

USES OF INTALITH CR 450MG TABLET

  • Used to treat depression

HOW INTALITH CR 450MG TABLET WORKS

INTALITH CR 450MG TABLET works by stabilising the levels of chemicals in your brain that influence your mood.

DIRECTIONS FOR USE

Take INTALITH CR 450MG TABLET as advised by your physician. Swallow this medicine, do not crush, or chew. Your doctor will decide the right dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking INTALITH CR 450MG TABLET unless your doctor advises you to stop.

SIDE EFFECTS OF INTALITH CR 450MG TABLET

COMMON

  • hand trembling
  • excessive urination
  • increased thirst
  • nausea
  • general discomfort (beginning of treatment)
  • dizziness
  • rash
  • difficulty walking
  • decreased appetite
  • vomiting
  • blurred vision

RARE

Stop taking INTALITH CR 450MG TABLET and contact your doctor immediately if you experience any of the following side effects:

  • changes in heart rhythm like slow, fast or irregular heartbeat
  • fever, confusion, agitation, shaking, abrupt contractions of muscles
  • neuroleptic malignant syndrome (fever with rigid muscles, agitation, confusion, sweating, or jerky muscle movements)
  • continuous headaches and/or visual disturbances
  • rhabdomyolysis (breakdown of muscles leading to kidney problems)
  • serious disturbance in mental abilities that results in confusion and reduced awareness of the environment
  • abnormal heartbeat, vomiting, diarrhea, drowsiness, muscle weakness or twitching, blurred vision, clumsiness, ringing in your ears
  • low blood sodium levels (excessive sweating, diarrhea)
  • Brugada Syndrome (feeling abnormal heartbeats)
  • increased pressure in the brain and swelling in the eye (severe headaches behind your eyes, ringing in the ears, blurred or double vision, brief periods of blindness)
  • allergic reaction (rash, trouble swallowing or breathing, swollen lips, face, throat or tongue)
  • cloudy or foamy urine
  • feeling dazed, delirious or loss of consciousness
  • memory problems
  • fits or seizures
  • involuntary eye movements
  • Benign/malignant kidney tumours in long-term treatment (microcysts, oncocytoma, or collecting duct renal carcinoma)
  • lichenoid drug reaction (eruption of the skin or mucous membranes)
  • hyperthyroidism (fast heartbeat, sweating, stress, increased appetite, weight loss, weakness, heat intolerance)
  • hypothyroidism (tiredness, cold skin, dry hair, thinning of hair or fingernails, hoarse voice, joint or muscle pain, weight gain)
  • hyperparathyroidism (increased thirst and urination, tiredness, depression, muscle aches or pains, bone or joint pain, upset stomach)
  • gastritis (indigestion, heartburn, nausea, vomiting, stomach pain, black tarry faeces, bloody stools, blood or dark bits in your vomit)
  • peripheral neuropathy (numbness, weakness, pain in the arms and legs)

HOW TO MANAGE SIDE EFFECTS

Loss Of Appetite

Eat when you are hungry. Eat smaller meals more often than usual. Snack only when you are hungry. Eat a protein-rich or other nutritious snack such as dried fruit and nuts. If appetite does not improve, contact your doctor.

Nausea And Vomiting

Take INTALITH CR 450MG TABLET with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods, sugary snacks, and aerated drinks. Avoid drinking too much liquid along with or before your meals, drink slowly in between meals. If nausea or vomiting does not get better, contact your doctor.

Skin Rash Or Itching

Avoid hot showers because hot water can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash gets worse.

WARNING & PRECAUTIONS

PREGNANCY
Contraindicated

INTALITH CR 450MG TABLET is not recommended if you are pregnant or trying to become pregnant. Consult your doctor for advice.

BREASTFEEDING
Contraindicated

INTALITH CR 450MG TABLET is not recommended if you are breast-feeding. Consult your doctor for advice.

DRIVING AND USING MACHINES
Use with Caution

Do not drive or operate any tools or machines, as INTALITH CR 450MG TABLET may cause dizziness or other nervous disorder, sleepiness, tiredness, numbness, paralysis, weakness or fits.

KIDNEY
Consult your doctor

INTALITH CR 450MG TABLET is not recommended for use in patients having severe kidney disease. If patients with mild or moderate renal impairment are being treated with INTALITH CR 450MG TABLET serum levels should be closely monitored. Consult your doctor for advice.

ALLERGY
Contraindicated

Do not take INTALITH CR 450MG TABLET if you are allergic to Lithium, or any of the other ingredients of this medicine.

LUNGS
Use with Caution

INTALITH CR 450MG TABLET should be used with caution in patients with breathing problems. Consult your doctor before taking it.

HEART DISEASE
Consult your doctor

INTALITH CR 450MG TABLET is not recommended for use in patients having irregular heartbeat or Brugada syndrome. INTALITH CR 450MG TABLET should be used with caution in patients with other heart diseases. Consult your doctor before taking it.

USE IN PEDIATRICS
Contraindicated

INTALITH CR 450MG TABLET is not recommended for use in children. Consult your child’s doctor for advice.

USE IN GERIATRICS
Use with Caution

INTALITH CR 450MG TABLET should be used with caution in elderly patients (above 65 years of age), especially those with decreased liver, kidney, or heart function. Consult your doctor for advice.

OTHERS

INTALITH CR 450MG TABLET is not recommended for use if you:

  • have an uncontrollable hypothyroidism  
  • have low sodium levels in the body  
  • have Addison’s disease
  • want to go on any kind of diet

Before taking INTALITH CR 450MG TABLET, inform your doctor if you:

  • have epilepsy (fits)
  • have continuous headaches with or without visual disturbances
  • have low levels of potassium, magnesium, and calcium in your blood
  • recently had or going to have a weight loss surgery
  • have cold
  • have gastroenteritis  
  • are not eating or drinking properly

INTERACTIONS

A. Drug-Drug interactions:

Before taking INTALITH CR 450MG TABLET, inform your doctor if you are taking any of the following medicines:

  • medicines used to treat bacterial infections (Ex. tetracyclines, metronidazole, parfloxacin, co-trimoxazole, trimethoprim, spectinomycin, erythromycin)
  • medicines used to treat pain and rheumatism (Ex. celecoxib, indomethacin, diclofenac, ibuprofen, aspirin)
  • medicines used to treat heart problems, high or low blood pressure or irregular heart rhythm (Ex. ramipril, lisinopril, losartan, irbesartan, empagliflozin, quinidine, procainamide, disopyramide, amiodarone, ajmaline, cibenzoline, hydroquinidine, azimilide, dofetilide, ibutilide, sotalol, methyldopa, amlodipine, diltiazem, ketanserin)
  • ranolazine (used for angina)
  • medicines used to treat allergy or inflammation (Ex. prednisolone, betamethasone, hydrocortisone)
  • furosemide, chlortalidone, indapamide, spironolactone, acetazolamide (used to promote salt and water excretion from body)
  • theophylline (used to treat asthma)
  • caffeine (CNS stimulant)
  • sodium bicarbonate (used to relieve heartburn)
  • medicines used to treat schizophrenia and other behavioural disorders (Ex. haloperidol, olanzapine, clozapine, amisulpride, pimozide, sertindole, mesoridazine, clozaril, droperidol, thioridazine)
  • medicines used to treat epilepsy (Ex. clonazepam, carbamazepine, phenytoin)
  • medicines used to treat depression (Ex. fluoxetine, paroxetine, amitriptyline)
  • muscle relaxants used in anaesthesia (Ex. pancuronium)
  • sumatriptan (medicine used to treat migraine)
  • arsenic trioxide (used to treat leukemia)
  • cisapride (used to treat stomach and bowel problems)
  • medicines used to treat malaria (Ex. halofantrine, mefloquine, artemisinin)
  • dolasetron (used to treat nausea and vomiting after chemotherapy)
  • medicines used to treat allergies (Ex. terfenadine, astemizole)
  • calcitonin (used to treat high blood calcium levels and acute bone loss)

Overdosage:

If you or anyone else accidentally takes too much of INTALITH CR 450MG TABLET consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are stomach pain, loss of appetite, nausea, vomiting, diarrhoea, blurred vision, excess urination, light headedness, shaking, muscle twitching or weakness, drowsiness, and feeling very tired.

SYNOPSIS

Drug :   Lithium
Pharmacological Category :   Mood stabilizer
Therapeutic Indication :   Manic depression
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep INTALITH CR 450MG TABLET out of reach of children
  • Do not store INTALITH CR 450MG TABLET above 25°C

FAQs ABOUT INTALITH CR 450MG TABLET

Q: Can INTALITH CR 450MG TABLET be used to treat depression?

A: Yes. It is used to treat depression. INTALITH CR 450MG TABLET also used to manage or control hypomania (less severe form of mania) and aggressive or self-harming behaviour.

Q: Can INTALITH CR 450MG TABLET be given to children?

A: INTALITH CR 450MG TABLET is not recommended for use in children. Consult your child’s doctor for advice.

Q: Can I take painkillers along with the INTALITH CR 450MG TABLET?

A: It is not advisable to take painkillers like non-steroidal anti-inflammatory drugs (Ex. celecoxib, indomethacin, diclofenac, ibuprofen) along with INTALITH CR 450MG TABLET as it may increase the amount of medicine in the body causing side effects. Consult your doctor before taking any other medicines with INTALITH CR 450MG TABLET.

Q: Can INTALITH CR 450MG TABLET cause headaches?

A: Yes. Headache is a possible side effect of INTALITH CR 450MG TABLET. In such case, drink plenty of water and get adequate rest. Try to be relaxed and stress free. Check with your doctor before taking any medicine for headache. Stop taking INTALITH CR 450MG TABLET and consult your doctor immediately if you experience continuous headaches with visual disturbances.

REFERENCES

1. KD. Tripathi. Drugs Affecting Renin Angiotensin System. Essentials of Medical Pharmacology. Eighth edition. 2019. Page – 474.

2. Rodrigo Machado-Vieira, Husseini K Manji, Carlos A Zarate Jr. The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis. National Library of Medicine. National Center for Biotechnology Information. PubMed Central. June 2009. [Accessed on 4th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2800957/

3. Krutika Chokhawala, Sarah Lee, Abdolreza Saadabadi. Lithium. National Library of Medicine. National Center for Biotechnology Information. PubMed Central. May 2022. [Accessed on 4th May 2022] https://www.ncbi.nlm.nih.gov/books/NBK519062/

4. Delpharm L’Aigle.  Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 4th May 2022] https://www.medicines.org.uk/emc/files/pil.10828.pdf

5. Wasdell Packaging Limited. Norgine Ltd. Hengoed. Delpharm L’Aigle. Delpharm Dijon. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed 4th May 2022] https://www.medicines.org.uk/emc/files/pil.10829.pdf

6. Delpharm Dijon. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 30th August 2022] https://www.medicines.org.uk/emc/files/pil.13162.pdf

7. West-Ward Pharmaceuticals Corp. U.S. Food & Drug Administration. [Revised in December 2018] [Accessed on 30th August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/017812s033,018421s032,018558s027lbl.pdf

8. Glenmark Pharmaceuticals Inc., LITHIUM CARBONATE ER- lithium carbonate tablet. Dailymed.com. [Revised in December 2019] [Accessed on 4th May 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=525a9d9b-cbb1-4644-a28a-8bba96f09348&type=display

9. Torrent Pharmaceuticals. [Revised in Feb 2022] [Accessed on 4th May 2022] https://www.torrentian.com/pisheet/Search.aspx

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 25 Feb 2023 | 05:28 PM(IST)

PRODUCT DETAILS
    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    LITHIUM CARBONATE 450MG (CR)
    Hsn Code
    30049099
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10 Tablet(s) in a Strip Mkt: Icon Life Sciences
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Intalith CR 450mg Tablet 10'S
Intalith CR 450mg Tablet 10'S Mkt: Intas Pharmaceuticals Ltd
₹ 32.39 MRP ₹ 39.50