INTRODUCTION
INDICONTIN contains Indapamide which belongs to a group of medicines called diuretics (water tablets). It works by causing the kidneys to get rid of unwanted water and salt from the body into the urine and thus helps in treating high blood pressure. INDICONTIN acts on the kidneys to boost the elimination of sodium, potassium and water in the urine thus resulting in increased urination. This reduces the fluid in blood vessels and body tissues and lowers blood pressure. Indapamide causes a slight increase in the amount of urine produced than the other diuretics. It also widens blood vessels so that blood passes through more easily.
The recommended dose is one tablet (2.5mg) each day which should be swallowed with a glass of water. It is advised that the tablet be taken in the morning or as directed by the physician. Do not take INDICONTIN if you are pregnant or breast feeding. Consult your doctor for advice. The side effects are inflammation of mucous membranes (Stevens-Johnson Syndrome), irregular heartbeat, tiredness, loss of appetite, feeling or being sick, swollen extremities, yellow skin (Symptoms of abnormal liver function).
USES OF INDICONTIN
- Treat high blood pressure
HOW INDICONTIN WORKS
Indapamide is a diuretic which acts on the kidneys to boost the elimination of sodium, potassium and water in the urine thus resulting in increased urination. This reduces the fluid in blood vessels and body tissues and lowers blood pressure.
DIRECTIONS FOR USE
Always take INDICONTIN exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water.
SIDE EFFECTS OF INDICONTIN
SERIOUS
- angioedema (swelling of the skin around the eyes, lips, tongue, hands or feet, shortness of breath or difficulty in swallowing)
- Severe skin reactions such as skin rash, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin
- inflammation of mucous membranes (Stevens-Johnson Syndrome)
- irregular heartbeat
- tiredness, loss of appetite, feeling or being sick, swollen extremities, yellow skin (Symptoms of abnormal liver function)
COMMON
- dermatological allergic reactions, such as skin rashes in patients with high sensitivity to allergy and asthmatic reactions
RARE
- feeling of tiredness, headache, pins and needles (paresthesia), vertigo
- gastrointestinal disorders such as nausea or constipation, dry mouth
HOW TO MANAGE SIDE EFFECTS
Nausea:
Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Constipation:
Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Diarrhea:
Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicine without consulting your doctor.
WARNING & PRECAUTIONS
PREGNANCY
INDICONTIN is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
INDICONTIN is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
INDICONTIN may make you feel tired or dizzy. If this happens do not drive or use any tools or machines
ALCOHOL
Avoid consumption of alcohol while taking this medicine.
KIDNEY
INDICONTIN should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LIVER
INDICONTIN should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
ALLERGY
Do not take INDICONTIN if you are allergic (hypersensitive) to Indapamide or any other ingredients in this medicine.
HEART DISEASE
If you have any heart related problems, consult your doctor for advice before taking this medicine.
OTHERS
Tell your doctor if you have,
- low levels of the potassium in your blood (hypokalaemia)
- suffer from gout
- or have ever suffered from an overactive parathyroid gland (hyperparathyroidism) leading to too much calcium in the blood
INTERACTIONS
Talk to your doctor if you are taking:
- lithium (used to treat depression)
- quinidine, hydroquinidine, disopyramide (medicines used for heart rhythm problem)
- bepridil (used to treat angina pectoris)
- laxatives
- medicines used to treat the mental disorders such as depression, anxiety or schizophrenia
- antibiotics used to treat infections
- vincamine injection
- pentamidine used to treat the certain types of pneumonia
SYNOPSIS
| Drug | : | Indapamide |
| Pharmacological Category | : | Diuretics |
| Therapeutic Indication | : | High blood pressure |
| Dosage Forms | : | Tablet, Capsule |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT INDICONTIN
What is INDICONTIN used for?
INDICONTIN is diuretic which is used to treat high blood pressure (hypertension).
Does INDICONTIN cause low potassium?
Yes, the most common side effects of INDICONTIN are fluid loss and low blood potassium.
Does INDICONTIN make you sleepy?
INDICONTIN may cause you to have an unusual feeling of tiredness when you begin to take it.
REFERENCES
1. Goodman and Gilman’s: The Pharmacological Basis of Therapeutics. Chapter – 25; Regulation of renal function and vascular volume; 12th ed. New York, New York: McGraw-Hill Medical, 2011. Page – 689.
2. Reyes AJ, Leary WP; Indapamaide: A review; [Published on Nov 1983] https://europepmc.org/article/med/6356402
3. S.C. Zentiva S.A; Electronic Medicines Compendium (EMC); [Revised on Oct 2020] [Accessed 06 Nov 2020] https://www.medicines.org.uk/emc/files/pil.4188.pdf
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