Hisone 10mg Tablet 10'S

Hormonal Therapy Rx required

Best Price*  ₹ 49.51
MRP ₹61.89
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Samarth Life Sciences Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

HISONE 10MG contains Hydrocortisone which belongs to the group of medicines called corticosteroids. It can be used as a replacement therapy for endogenous corticosteroids in children suffering from insufficient production of corticosteroids due to congenital adrenal hyperplasia, adrenal insufficiency or doubtful adrenocortical reserve. It can also be used for adding hydrocortisone after surgeries, trauma, injuries or other stressful conditions. It is also used to treat severe asthma and other allergic reactions or serious illness in both adults and in children.

Corticosteroids are the substance that naturally produced in your body and helps to maintain your health and well-being. Supplementing your body with extra corticosteroids can help to treat various illnesses and inflammatory conditions. Hydrocortisone binds to the corticosteroid receptors of adrenal glands and mediates various physiological functions. It also blocks the production of various inflammatory mediators responsible for causing inflammation and allergies. 

HISONE 10MG can be taken with or without food. Do not reduce the dose or stop taking this medicine without informing your doctor, as it may result in withdrawal symptoms such as muscle/joint pain, fever and general discomfort. At the same time, do not take too much of this medicine, because it can lead to overdosage. Symptoms of overdosage includes nausea, vomiting, fluid retention, high blood sugar or GI bleeding.

While taking this medicine, inform your doctor immediately if you experience any signs of mental problems such as depression or suicidal thoughts. Your doctor might reduce your dose or suggest an alternative therapy. Stay away from people having chickenpox, shingles or measles, because infections are easier to get and harder to spot while taking HISONE 10MG. 

Do not take this medicine if you have any bacterial, viral or fungal infections. Before taking this medicine inform your doctor if you have any liver, kidney, heart or stomach problems. While giving this medicine to premature infants and children, proper dose titration and careful monitoring of heart function and growth are required. Pregnant and breastfeeding women should inform their doctor before taking HISONE 10MG as a precaution.

USES OF HISONE 10MG

  • Used as a replacement therapy for corticosteroid deficiency in children with congenital adrenal hyperplasia, adrenal insufficiency or doubtful adrenocortical reserve
  • Supplements corticosteroids during or after surgeries, trauma, injuries or other stressful conditions in adults and in children
  • Treat severe asthma and other allergic reactions in both adults and in children

HOW HISONE 10MG WORKS

Hydrocortisone is a corticosteroid hormone receptor agonist. It binds to the corticosteroid receptors of adrenal glands and mediates various physiological functions such as gluconeogenesis, protein catabolism, renal excretion of calcium and capillary wall stability. It also works by inhibiting the production of various inflammatory mediators and chemical messengers which are responsible for causing inflammation (redness and swelling) and allergies (asthma, hay fever).

DIRECTIONS FOR USE

Take HISONE 10MG as directed by your physician. It can be taken with or without meals. Swallow the medicine as whole with a sip of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and health condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF HISONE 10MG

SERIOUS

  • allergic reactions (such as skin rash, swelling of the face or wheezing)
  • an irregular heartbeat
  • muscle spasms or cramps
  • signs of pseudo-tumor-cerebri in children (increased cranial pressure accompanied by headaches with vomiting, listlessness and drowsiness)
  • bleeding of ulcers (indicated by stomach, bleeding from the anus, black stools or blood vomiting)
  • acute pancreatitis
  • worsening of eyesight
  • thrombosis (a blood clot in the veins of legs)
  • thromboembolism (a blood clot in lung)
  • heart failure

COMMON

  • mental problems (such as depression, suicidal thoughts, mania, anxiety, confusion, difficulty in sleeping, loss of memory, or hallucinations)
  • infections
  • muscle weakness or pain

HOW TO MANAGE SIDE EFFECTS

Mental health problems:

This is a common side effect in both adults and in children and need to be monitored very carefully. Contact your doctor immediately if you experience any signs of mental problems such as depression or suicidal thoughts. Your doctor might reduce your dose or suggest an alternative therapy.

WARNING & PRECAUTIONS

PREGNANCY

HISONE 10MG should be used with caution in pregnant women. Your doctor will decide whether you should use this medicine or not.

BREASTFEEDING

HISONE 10MG should be used with caution in breastfeeding women. Consult your doctor before taking this medicine.

DRIVING AND USING MACHINES

Do not drive or operate any tools or machines if your ability is affected by this medicine.

KIDNEY

HISONE 10MG should be taken with caution in patients with kidney problems. Consult your doctor for advice.

LIVER

HISONE 10MG should be taken with caution in patients with liver problems. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to hydrocortisone.

HEART DISEASE

HISONE 10MG should be taken with caution in patients suffering from congestive heart disease, a recent heart attack, high blood pressure or other heart problems. Consult your doctor for advice.

OTHERS

Before taking HISONE 10MG, inform your doctor if you have the following conditions:

  • ever had severe depression or bipolar disorder
  • tuberculosis or septicaemia (bacterial infections) in the past
  • stomach ulcers or other digestive problems (e.g. ulcerative colitis)
  • chicken pox or shingles (viral infections)
  • poor immune system
  • ocular herpes simplex (viral eye infection)
  • muscle weakness following steroidal administration in the past
  • epilepsy
  • thrombophlebitis (redness and swelling of veins)
  • exanthematous disease (allergic skin reaction)
  • metastatic carcinoma
  • amoebic dysentery or and strongyloidiasis (an infestation of gut worm)
  • diabetes
  • glaucoma (increased pressure in the eyes)
  • myasthenia gravis (muscle weakness)
  • osteoporosis (thinning of bones)
  • hypothyroidism (decreased thyroid levels)
  • recently got vaccinated or going to receive any vaccinations

INTERACTIONS

Talk to your doctor, if you are taking

  • medicines used to treat epilepsy (e.g. phenytoin, phenobarbital, carbamazepine and primidone)
  • ephedrine (a decongestant used to treat cold and cough)
  • medicines used to treat tuberculosis (e.g. rifabutin or rifampicin)
  • medicines used for blood thinning (e.g. warfarin)
  • medicines used to treat fungal infections (e.g. amphotericin and ketoconazole)
  • medicines used to treat heart failure (e.g. digoxin, furosemide or bumetanide), high blood pressure (e.g. atenolol, captopril) or other heart disease (e.g. guanethidine, hydralazine, isosorbide mononitrate, isosorbide dinitrate and theophylline)
  • sympathomimetics (used to treat cold and cough, asthma or low blood pressure) such as bambuterol, fenoterol, formoterol, ritodrine, salbutamol, salmeterol, terbutaline
  • non-steroidal anti-inflammatory drugs (used to treat pain and inflammation) such as ibuprofen, diclofenac or naproxen
  • medicines used to treat diabetes (e.g. insulin, metformin)
  • aspirin (used to treat pain and blood clotting)
  • diuretics (used to increase urine output) e.g. furosemide
  • aminoglutethimide (used to treat cancer)
  • erythromycin (used to treat bacterial infection)
  • oral contraceptive pills (birth control pills)
  • hormone replacement therapy
  • somatropin (a hormone used to increase growth)
  • calcium supplements
  • sodium phenylbutyrate (used to correct disorders of urea cycle)
  • ritonavir and cobicistat (a synergistic combination used to treat HIV infection)
  • methotrexate (used to treat cancer or rheumatoid arthritis)
  • ciclosporin (used to treat psoriasis or prevent graft rejection)
  • minoxidil (used to increase hair growth)

SYNOPSIS

Drug :   Hydrocortisone acetate
Pharmacological Category :   Corticosteroid receptor agonist
Therapeutic Indication :   Corticosteroid insufficiency
Dosage Forms :   Tablet, Cream, Lotion, Rectal Foam, Enema, Inhaler

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT HISONE 10MG

Is HISONE 10MG a steroid?

Yes. This medicine is a corticosteroid use to treat various allergic and inflammatory conditions and metabolic disorders.

Is HISONE 10MG safe during pregnancy?

Consult your doctor before taking any medicine if you are pregnant or think you may be pregnant. Your doctor will decide whether you should take this medicine or not depending upon the severity of the disease.

What happens if I take too much of this medicine?

Take this medicine only as directed by your physician. If you or anyone accidentally took too much of this medicine contact your doctor immediately. Symptoms of overdosage might include nausea, vomiting, fluid retention, high blood sugar or GI bleeding.

Is HISONE 10MG addictive?

This medicine is not habit-forming in nature, but it may cause withdrawal symptoms such as muscle/joint pain, fever and general discomfort if the dose is reduced or stopped abruptly. In such cases, contact your doctor.

REFERENCES

1. KD. Tripathi. Corticosteroids. Essentials of medical pharmacology. Seventh edition. 2013. Page – 288 & 290.

2. Bernard P. Schimmer and John. W. Funder. ACTH, Adrenal steroids and Pharmacology of the Adrenal Cortex. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1228-1229.

3. Gerald G. Briggs and Roger K. Freeman. H. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 1875-1886.

4. Shire. Once-daily Oral Modified Release Hydrocortisone in Patients With Adrenal Insufficiency. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on November 2020] [Accessed 4th January 2021] https://clinicaltrials.gov/ct2/show/NCT00915343

5. Diurnal Limited. An Investigational Study of Hydrocortisone. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on April 2017] [Accessed 4th January 2021] https://clinicaltrials.gov/ct2/show/NCT01960530

6. Jude Madathilethu, Matthew Roberts, Matthew Peak, Joanne Blair, Rebecca Prescott and James L Ford. Content uniformity of quartered hydrocortisone tablets in comparison with mini-tablets for paediatric dosing. NCBI; PMC US National Library of Medicine, National Institute of Health. January 2018. [Accessed 4th January 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843003/

7. Sivapriya Ramamoorthy and John A. Cidlowski. Corticosteroids-Mechanisms of Action in Health and Disease. NCBI; PMC US National Library of Medicine, National Institute of Health. February 2017. [Accessed 4th January 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4662771/

8. Tiofarma BV. Electronic Medicines Compendium (EMC); [Revised on July 2020] [Accessed 4th January 2021] https://www.medicines.org.uk/emc/files/pil.5035.pdf

9. Anfarm Hellas SA. Electronic Medicines Compendium (EMC); [Revised on May 2019] [Accessed 4th January 2021] https://www.medicines.org.uk/emc/files/pil.3065.pdf

10. Mibe GmbH Arzneimittel. Electronic Medicines Compendium (EMC) [Revised on May 2018] [Accessed 4th January 2021] https://www.medicines.org.uk/emc/files/pil.10763.pdf

USEFUL DIAGNOSTIC TESTS

  • Absolute Eosinophil Count
  • Peripheral Smear Examination
  • Total IgE

PRODUCT DETAILS

    Net Qty
    1
    Item Weight
    17.5
    Ingredient
    HYDROCORTISONE 10MG
    Hsn Code
    30043200
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Hisone 10mg Tablet 10'S

Hisone 10mg Tablet 10'S Mkt: Samarth Life Sciences Pvt Ltd

M.R.P.: Rs.61.89
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