INTRODUCTION

HETRAZAN 100MG TABLET contains Diethylcarbamazine which belongs to the group of medicines called Anthelmintics. It is used to treat filarial infections, tropical eosinophilia and toxocariasis. It is also used to prevent loiasis (eye worm infections).

Filariasis is an infectious tropical disease caused by any one of several thread-like parasitic roundworms.

HETRAZAN 100MG TABLET should be used with caution in patients with seizures and liver diseases. Contact your doctor before taking it.

HETRAZAN 100MG TABLET is not recommended for use in patients with kidney or heart disease. Contact your doctor before taking it.

HETRAZAN 100MG TABLET is generally not recommended for use in pregnant women. Contact your doctor before taking it. HETRAZAN 100MG TABLET is generally not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before taking it.

There is only limited information available on the use of HETRAZAN 100MG TABLET in geriatric patients. Consult your doctor before taking it.

The most common side effects of taking HETRAZAN 100MG TABLET are nausea and vomiting. Contact your doctor if your symptoms got worse.

USES OF HETRAZAN 100MG TABLET

Used to treat and prevent:

• filarial infections
• tropical eosinophilia
• toxocariasis
• loiasis (eye worm infection)

HOW HETRAZAN 100MG TABLET WORKS

HETRAZAN 100MG TABLET functions by destroying the infection-causing parasites and preventing their future growth.

DIRECTIONS FOR USE

Take HETRAZAN 100MG TABLET as advised by your physician. Swallow the medicine. Do not crush or chew the medicine. Based on your age, body weight and medical condition, your doctor will choose the appropriate dose and duration for you.

SIDE EFFECTS OF HETRAZAN 100MG TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea and Vomiting:

Take the medicine, with or just after a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if the symptoms did not improve.

Headache:

Try to take rest and don’t involve yourself in exertive activities. Apply a pain-relieving balm to your forehead. If the headache does not improve, consult with your doctor.

WARNING & PRECAUTIONS

PREGNANCY

HETRAZAN 100MG TABLET is generally not recommended for use in pregnant women. Contact your doctor before taking it.

BREASTFEEDING

HETRAZAN 100MG TABLET is generally not recommended for use in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel drowsy after taking HETRAZAN 100MG TABLET.

KIDNEY

HETRAZAN 100MG TABLET is not recommended for use in patients with kidney disease. Contact your doctor before taking it.

LIVER

There is limited information available on the use of HETRAZAN 100MG TABLET in patients with liver disease. Consult your doctor before taking it.

ALLERGY

Do not take HETRAZAN 100MG TABLET if you are allergic to Diethylcarbamazine or intolerance to lactose or other ingredients of the medicine.

HEART DISEASE

HETRAZAN 100MG TABLET is not recommended for use in patients with heart diseases. Contact your doctor before taking it.

INTERACTIONS

A. Drug - Drug interaction:

Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription, vitamin supplements or herbal products.

Overdosage:

If you or anyone else accidentally takes too much of HETRAZAN 100MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are headache, dizziness, drowsiness, nausea, vomiting and, in serious cases, it may cause convulsions.

SYNOPSIS

MORE INFORMATION

• Keep HETRAZAN 100MG TABLET out of the sight and reach of children
• Store HETRAZAN 100MG TABLET below 30°C

FAQs ABOUT HETRAZAN 100MG TABLET

What type of drug is HETRAZAN 100MG TABLET?

HETRAZAN 100MG TABLET contains Diethylcarbamazine which belongs to the group of medicines called Anthelmintics.

Can I use HETRAZAN 100MG TABLET in children?

Yes, HETRAZAN 100MG TABLET should be used with caution in children, your doctor will give the right dose depending on your child’s age, body weight and disease condition. Contact your doctor before taking it.

What are the side effects of taking HETRAZAN 100MG TABLET?

The most common side effects of taking HETRAZAN 100MG TABLET are nausea and vomiting. Contact your doctor if your symptoms got worse.

Can I use HETRAZAN 100MG TABLET in pregnancy?

No. HETRAZAN 100MG TABLET is generally not recommended for use in pregnant women. Contact your doctor before taking it.

Is HETRAZAN 100MG TABLET safe?

HETRAZAN 100MG TABLET is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose.

Can the use of HETRAZAN 100MG TABLET cause drowsiness?

Yes, HETRAZAN 100MG TABLET may cause drowsiness. Avoid driving, operating on machinery, working at heights or participating in potentially dangerous activities, especially during the initial days of your treatment. However, if your condition does not improve, consult your doctor.

REFERENCES

1. H. P. Rang, J.M. Ritter, R. J. Flower, G. Henderson. Anthelmintic drugs. Rang and Dale's Pharmacology. Eighth edition. 2014. Page – 674.

2. KD. Tripathi. Anthelmintic Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 853.

3. Padmaja Udayakumar. Anthelmintics and Drugs used in Scabies and Pediculosis. Pharmacology for Pharmacy Students. 2018. 631-632.

4. Whalen, K., Finkel, R., & Panavelil, T. A. Anthelmintic drugs. Lippincott illustrated reviews: Pharmacology. Sixth edition. 2015. Page – 562.

5. Ottesen EA. Description, mechanisms and control of reactions to treatment in the human filariases. Ciba Found Symp. 1987. [Accessed 18 July 2022] https://pubmed.ncbi.nlm.nih.gov/3297558/

6. OE Orisakwe, NA Ilondu, OJ Afonne, SI Ofoefule, CN Orish. Acceleration of body clearance of diethylcarbamazine by oral activated charcoal. Pharmacological Research. Aug 2000. [Accessed on 18th July 2022] https://pubmed.ncbi.nlm.nih.gov/10887047/

7. GlaxoSmithKline Pharmaceuticals Limited. Diethylcarbamazine Citrate. [Revised in June 2021] [Accessed on 18th July 2022] https://india-pharma.gsk.com/media/6339/banocide-and-banocide-forte.pdf

8. Sanofi Aventis France. Diethylcarbamazine. [Revised in October 2016] [Accessed on 18th July 2022] https://extranet.who.int/pqweb/sites/default/files/NT001Part3v1.pdf

9. Pfizer Ltd. Diethylcarbamazine. [Revised in 2018] [Accessed on 18th July 2022] https://labeling.pfizer.com/ShowLabeling.aspx?id=14804

USEFUL DIAGNOSTIC TESTS

• complete blood test
• peripheral smear count
• filarial antibody

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 29 Sep 2022 | 09:47 AM(IST)