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Herperax 200mg Tablet 5'S
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INTRODUCTION
HERPERAX 200MG TABLET contains Acyclovir, which belongs to the group of medicines called Antivirals. It is used to treat chickenpox, shingles, cold sores, genital herpes and other herpes simplex infections to prevent infections in people with a weakened immune system.
Cold sores, (a virus causing contagious sores, most often around the mouth or on the genitals), genital herpes (a common sexually transmitted infection caused by the herpes simplex virus and symptoms include genital pain and sores, pain, itching and small sores).
Before taking HERPERAX 200MG TABLET inform your doctor if you have kidney problems. HERPERAX 200MG TABLET should be used with caution among pregnant or breastfeeding women. Consult your doctor before taking HERPERAX 200MG TABLET.
The most common side effects of taking HERPERAX 200MG TABLET are headache, dizziness, feeling or being sick, diarrhea, stomach pain and rashes. Contact your doctor if the symptom persists.
USES OF HERPERAX 200MG TABLET
HERPERAX 200MG TABLET is used in the following conditions:
- Treats chickenpox and Herpes zoster (shingles)
- Treats cold sores, genital herpes
- Treats herpes simplex infections
- Prevents problems in those people infected with a virus
- Prevents infections in low immunity patients
HOW HERPERAX 200MG TABLET WORKS
HERPERAX 200MG TABLET works by killing or stopping the growth of viruses (herpes virus). It has a higher affinity for viral DNA cells than human DNA cells and incorporates into the viral DNA and causes DNA chain termination and inactivation, leading to the death of cells.
DIRECTIONS FOR USE
Take HERPERAX 200MG TABLET as advised by your physician. Swallow the medicine by mouth with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
SIDE EFFECTS OF HERPERAX 200MG TABLET
COMMON
- headache, dizziness
- nausea, vomiting, diarrhea, stomach pain
- skin reaction after exposure to light (photosensitivity), itchy skin
- feeling tired
- fever
UNCOMMON
- itchy, hive-like rash
- hair loss
RARE
- effects on blood & urine tests
- increase in liver enzymes
HOW TO MANAGE SIDE EFFECTS
Headache:
Take rest and drink plenty of fluids. If not subsided. Consult your doctor if your symptom gets worse or persist.
Diarrhea:
Drink lots of fluids, such as water or fruit juice to keep you hydrated. Do not consume any medicine on your own without consulting your doctor.
Stomach pain:
Try to rest and relax. Eat smaller meals but take them frequently. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.
Dizziness:
If HERPERAX 200MG TABLET makes you feel dizzy, take rest until you feel better. Do not drive or operate machines.
Nausea or vomiting:
Take simple meals and do not eat rich or spicy food.
Sensitivity to sunlight:
Stay out of the bright sun and use sun creams (SPF-15) when going outside. If the symptom does not improve, contact your doctor.
Itchy skin:
Try to use an unscented moisturiser. If the symptom does not improve, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
HERPERAX 200MG TABLET should be used with caution in pregnant women. Consult your doctor before taking it.
BREASTFEEDING
HERPERAX 200MG TABLET should be used with caution in breastfeeding women. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizzy, drowsiness or asleep after taking HERPERAX 200MG TABLET.
KIDNEY
HERPERAX 200MG TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking HERPERAX 200MG TABLET.
ALLERGY
Do not take HERPERAX 200MG TABLET if you are allergic to Acyclovir, valacyclovir or any of the other ingredients of this medicine.
OTHERS
HERPERAX 200MG TABLET is not recommended for use if you:
- have thrombotic thrombocytopenic purpura/haemolytic uremic syndrome (TTP/HUS)
- renal failure
Before taking HERPERAX 200MG TABLET, inform your doctor:
- if you have a low resistance to disease (immune deficiency)
- if you are taking nephrotoxic drugs (Ex. amphotericin B and aminoglycoside antibiotics)
Use in pediatrics:
NA
Use in geriatrics:
HERPERAX 200MG TABLET should be used with caution in elderly patients (aged above 75 years). Consult your doctor before taking HERPERAX 200MG TABLET.
INTERACTIONS
A. Drug - Drug interactions:
Before taking HERPERAX 200MG TABLET, inform your doctor if you are taking any of the following medicine:
- probenecid (used to treat gout)
- cimetidine (used to treat stomach ulcers)
- drugs acting on the immune system (Ex. mycophenolate mofetil)
- amikacin, amphotericin B, atovaquone, lumefantrine, mefloquine, azithromycin, capreomycin, caspofungin, clarithromycin, clindamycin, doxycycline, erythromycin (used to treat infections)
- antivirals Ex. valacyclovir, valganciclovir, ganciclovir, tenofovir, cidofovir (used to treat viral infections)
- albendazole (used to treat parasitic infections)
- dapsone, isoniazid (used to treat mycobacterial infections)
- antifungals Ex. fluconazole, itraconazole
B. Drug - Food interaction:
NA
Overdosage:
If you or anyone else accidentally take too much of HERPERAX 200MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are agitation, coma, seizures, lethargy etc.
SYNOPSIS
| Drug | : | Acyclovir |
| Pharmacological Category | : | Antivirals |
| Therapeutic Indication | : | Chickenpox, shingles, herpes simplex virus |
| Dosage Forms | : | Tablet, Suspension, Syrup, Infusion, Injection, Cream, Ointment, Eye- ointment |
MORE INFORMATION
- Keep HERPERAX 200MG TABLET out of the sight and reach from children
- Store HERPERAX 200MG TABLET below 25°C
FAQs ABOUT HERPERAX 200MG TABLET
Can HERPERAX 200MG TABLET be used to treat Urinary Tract Infections?
Yes. HERPERAX 200MG TABLET may be used to treat cystitis caused by the herpes simplex virus. Consult your doctor before taking HERPERAX 200MG TABLET.
What precautions do I need to follow while taking HERPERAX 200MG TABLET?
Patients taking HERPERAX 200MG TABLET must inform their doctor about their pre-existing disease conditions like kidney, heart or liver problems and if they are elderly above 65 years.
Can HERPERAX 200MG TABLET be used on pregnancy?
Yes. HERPERAX 200MG TABLET should be used with caution in pregnant women. Consult your doctor before taking HERPERAX 200MG TABLET.
Who should avoid taking HERPERAX 200MG TABLET?
HERPERAX 200MG TABLET is not recommended for patients having kidney diseases or elderly above 65 years and patients with allergic history to acyclovir. Consult your doctor before taking HERPERAX 200MG TABLET.
How long does it take for HERPERAX 200MG TABLET to show its effects?
HERPERAX 200MG TABLET works within 24-48 hours of administration.
Can HERPERAX 200MG TABLET treat a bacterial infection?
No. HERPERAX 200MG TABLET is an antiviral drug used to treat herpes simplex virus, chicken pox and shingles. Talk to your doctor before taking HERPERAX 200MG TABLET.
REFERENCES
1. KD Tripathi. Antiviral drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 799
2. Laurence L. Brunton, Randa Hilal-Dandan, Bjorn C. Knollman, Antiviral agents (Non-retroviral), Goodman & Gillman’s: The pharmacological basics of therapeutics, 13th edition. 2018. Page – 1105
3. Terapia S.A & Sun Pharmaceutical Industries Europe BV. Electronic Medicines Compendium (EMC). [Revised in October 2019] [Accessed on 18th April 2022] https://www.medicines.org.uk/emc/files/pil.4336.pdf
4. Terapia S.A. & Sun Pharmaceutical Industries Europe BV. Electronic Medicines Compendium (EMC). [Revised in October 2019] [Accessed on 18th April 2022] https://www.medicines.org.uk/emc/files/pil.4335.pdf
5. GlaxoSmithKline. U.S. Food & Drug Administration. [Revised in June 2005] [Accessed on 18th April 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/018828s030,020089s019,019909s020lbl.pdf
6. Acyclovir. CDSCO. [Revised in September 2010] [Accessed on 18th April 2022] https://cdscoonline.gov.in/CDSCO/Drugs
7. Significant drug interactions for drugs used to treat or prevent opportunistic infections https://clinicalinfo.hiv.gov/en/guidelines/pediatric-opportunistic-infection/table-5-significant-drug-interactions-drugs-used-treat
8. Drugbank. Mechanism of action of acyclovir https://go.drugbank.com/drugs/DB00787
USEFUL DIAGNOSTIC TESTS
- Herpes Simplex Virus 1 DNA PCR
- Herpes Simplex Virus 1 IgG
- Herpes Simplex Virus 2 DNA PCR
- Herpes Simplex Virus 2 IgG
- Herpes Simplex Virus 2 IgM
- Varicella Zoster IgG
- Varicella Zoster IgM
AUTHOR DETAILS
Written By Dr. Dhivakaran R, BDS
Last updated on 20 Oct 2022 | 03:30 PM(IST)
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