INTRODUCTION

HALOCON contains Halobetasol propionate which belongs to the group of medicines called topical corticosteroids. It is indicated for the topical treatment of a variety of skin conditions such as skin rash, eczema, dermatitis and psoriasis. Halobetasol is a super-high potency corticosteroid with anti-inflammatory and antipruritic properties. It can effectively reduce swelling, itching and redness associated with allergic skin conditions.

This medicine is for external use only. Avoid contact of this medicine with your eyes, ears, nose or mouth. If contact happens, rinse it thoroughly with plenty of water. Do not cover the treated area unless directed by physician. HALOCON should not be used on the face, groin, or in the axillae. This medicine should not be used for more than 2 weeks at a time due to the risk of hypothalamic-pituitary adrenal (HPA) axis suppression. If you cannot see any improvement within 2 weeks of therapy, inform your doctor. Your doctor might suggest an alternative therapy.

The most common side effects of this medicine are burning sensation, itching or redness at application site. These symptoms are usually temporary and disappears within a few days of treatment.  Before applying this medicine, inform your doctor if you are pregnant or breastfeeding. Do not apply this medicine if you have certain other type of skin disorders such as rosacea or perioral dermatitis. HALOCON is strictly not recommended for use in children below 12 years of age. Consult your doctor for advice before taking.

USES OF HALOCON

• Treats skin rash, eczema, dermatitis and psoriasis

HOW HALOCON WORKS

Halobetasol has anti-inflammatory, antipruritic and vasoconstrictive properties. It works by inducing the production of phospholipase A2 inhibitory proteins, which are responsible for the biosynthesis of the common precursor arachidonic acid and its potent mediators of inflammation such as prostaglandins and leukotrienes. This leads to a reduction in inflammation, itching, and redness associated with skin rash, eczema, dermatitis and psoriasis.

DIRECTIONS FOR USE

Apply a thin layer of this medicine to the affected skin once or twice daily, as directed by your physician. It is for external use only. Avoid contact of this medicine with your eyes, ears, nose or mouth. If contact happens, rinse it thoroughly with plenty of water. Do not cover the treated area unless directed by physician. Do not apply this medicine on the face, groin, or in the axillae. This medicine should not be used for more than 2 weeks at a time, as it may result in the risk of HPA axis suppression. If you cannot see any improvement within 2 weeks of therapy, inform your doctor.

SIDE EFFECTS OF HALOCON

HOW TO MANAGE SIDE EFFECTS

Application site reaction (itching, burning or redness):

Avoid hot showers because hot water can irritate the skin. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If it does not get better, speak to a doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor about all the medicines you use, including non-prescription and prescription medicines and herbal supplements.

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT HALOCON

Can HALOCON be used on face?

No. Do not apply this medicine on your face, groin, or in the axillae. Consult your doctor before application.

Can HALOCON be used for acne?

It is only used to treat skin conditions such as skin rash, eczema, dermatitis and psoriasis. Consult your doctor before taking any medicine to treat acne.

Can HALOCON be used on children?

No. It is strictly not recommended for use in children below 12 years of age. Consult your doctor before taking.

REFERENCES

1. KD. Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895-896.

2. Craig Burkhart, Dean Morrell and Lowell Goldsmith. Dermatological pharmacology. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1806 – 1807.

3. Azidus Brasil. Effectiveness and Safety of Topical Halobetasol Propionate in the Treatment of Patients with Psoriasis (halobetasol). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on September 2010] [Accessed 10th December 2020] https://clinicaltrials.gov/ct2/show/NCT00715975

4. Therapeutics, Inc. A Study to Determine the Efficacy and Safety of Halobetasol Propionate Lotion 0.05% in Subjects with Plaque Psoriasis. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on May 2016] [Accessed 10th December 2020] https://clinicaltrials.gov/ct2/show/NCT01610596

5. Jeffrey Bernhard, Claire Whitmore, Cynthia Guzzo, Irwin Kantor, Robert E.Kalb, Charles Ellis, Edmund H.Schwartzel and John R.GibsonMB. Evaluation of halobetasol propionate ointment in the treatment of plaque psoriasis: Report on two double-blind, vehicle-controlled studies. Sciencedirect.com. November 2008. [Accessed 10th December 2020] https://www.sciencedirect.com/science/article/abs/pii/0190962291703202

6. RANBAXY. U.S. Food & Drug Administration. [Revised on March 2012] [Accessed 10th December 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019968s011lbl.pdf