Gravitor Tablet 10'S

Myasthenia Gravis Rx required

Best Price* ₹ 164.80 MRP ₹ 206.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Sun Pharmaceutical Industries Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

GRAVITOR 60MG contains Pyridostigmine which belongs to the group of medicines called Anticholinesterases. It is used to treat myasthenia gravis and paralytic ileus (paralysis of digestive tract muscles). It can also be used to treat urinary retention after surgery (inability to urinate due to an anaesthetic or certain types of surgery). Myasthenia gravis is an immune system disease which prevents messages from the brain from reaching the muscles, causing muscles to become tired and weak, in severe cases it causes muscles to be paralyzed.

Pyridostigmine works by preventing the breakdown of a chemical called acetylcholine, which is required to stimulate muscle movement by improving the communication between nerves and muscles.

Do not take GRAVITOR 60MG if your digestive or urinary tract is obstructed. Before taking GRAVITOR 60MG, inform your doctor if you have kidney, heart, or thyroid problems, stomach ulcer, fits, or parkinson’s disease. GRAVITOR 60MG should be used in pregnant women only if considered necessary by your doctor. GRAVITOR 60MG should be used with caution among breastfeeding women, therefore consult your doctor before taking it. Your doctor will prescribe the right dose of GRAVITOR 60MG for your child depending on age, body weight and health condition. The most common side effects of taking GRAVITOR 60MG are nausea, vomiting, diarrhea, stomach cramps or pains, increased saliva, chest tightness, low blood pressure, muscle cramps and twitching. Contact your doctor if any of the symptoms worsen.

USES OF GRAVITOR 60MG

Used to treat:

  • myasthenia gravis
  • paralytic ileus
  • urinary retention after surgery

HOW GRAVITOR 60MG WORKS

GRAVITOR 60MG works by preventing the breakdown of a chemical called acetylcholine, which is required to stimulate muscle movement by improving the communication between nerves and muscles.

DIRECTIONS FOR USE

Take GRAVITOR 60MG as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking GRAVITOR 60MG unless your doctor advises you to stop.

SIDE EFFECTS OF GRAVITOR 60MG

COMMON

  • nausea, vomiting
  • diarrhea, stomach cramps or pains
  • increased saliva
  • chest tightness, low blood pressure
  • muscle cramps and twitching

RARE

  • skin rash

Stop taking GRAVITOR 60MG and contact your doctor immediately if you experience any of the following side effects:

  • allergic reaction (sudden wheeziness, trouble breathing, swelling of the eyelids, face or lips, rash or itching affecting your whole body)
  • cholinergic crisis (visual disturbance, more than normal tear or phlegm production, irregular heartbeat, rash, too much sweating, shaking, sudden urgency to urinate)

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to simple meals. Avoid eating oily or spicy foods. If nausea does not improve, contact your doctor.

Vomiting:

Get adequate rest. Drink sufficient fluids, especially water. Have small sips if you feel sick. Eat when you feel hungry or when to like to eat, in smaller quantities. Avoid eating oily or fried foods. Do not take any medicine for vomiting without asking your doctor. If vomiting does not improve, contact your doctor.

Diarrhea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not take any medicine on your own to treat diarrhea without consulting your doctor. If diarrhea does not improve, contact your doctor.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller meals more frequently. Keep a heat pad on your stomach. If the stomach pain does not improve, contact your doctor.

WARNING & PRECAUTIONS

PREGNANCY

GRAVITOR 60MG should be used in pregnant women only if considered necessary by your doctor. Consult your doctor before taking it.

BREASTFEEDING

GRAVITOR 60MG should be used with caution in breastfeeding women as a small amount is passed in the breast milk. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Consult your doctor if you feel any side effect during treatment with GRAVITOR 60MG that may stop you from driving or using machines.

KIDNEY

GRAVITOR 60MG is not recommended for use in patients who cannot pass urine because of an obstruction. GRAVITOR 60MG should be taken with caution in patients with kidney disease or impairment. Consult your doctor before taking it.

ALLERGY

Do not take GRAVITOR 60MG if you are allergic to Pyridostigmine or any of the other ingredients of this medicine.

LUNGS

GRAVITOR 60MG should be used with caution in patients with obstructive respiratory diseases like bronchial asthma or chronic obstructive pulmonary disease (COPD). Consult your doctor before taking it.

HEART DISEASE

GRAVITOR 60MG should be taken with caution in patients with slow heart rate, a recent blockage in a blood vessel to the heart, low blood pressure, or irregular heartbeat. Consult your doctor before taking it.

OTHERS

GRAVITOR 60MG is not recommended for use, if you:

  • have twisted or obstructed digestive tract

Before taking GRAVITOR 60MG, inform your doctor if you:

  • have fits
  • have stomach ulcer
  • have parkinson’s disease
  • have vagotonia (a disruption of the vagus nerve causing constipation, sweating and muscle cramps)
  • have an overactive thyroid
  • had a surgery to remove your thymus gland
  • intolerance to some sugars

Use in pediatrics:

Your doctor will prescribe the right dose of GRAVITOR 60MG for your child, depending on age, body weight and health condition.

Use in geriatrics:

GRAVITOR 60MG should be used with caution in elderly patients (aged above 65 years) with irregular heartbeat or other heart condition. Consult your doctor before taking it.

INTERACTIONS

A. Drug - Drug interactions:

Before taking GRAVITOR 60MG, inform your doctor if you are taking any of the following medicines: 

  • medicines used to treat vomiting or diarrhoea (Ex. atropine, hyoscine)
  • medicines used to relax muscles during surgery (Ex. pancuronium, vecuronium, suxamethonium)
  • methylcellulose (used to treat constipation)
  • medicines used to treat bacterial infections (Ex. amikacin, gentamicin)
  • medicines used to treat irregular heartbeat (Ex. quinidine, amiodarone)
  • medicines used to treat inflammatory conditions (Ex. prednisolone, beclomethasone)
  • medicines used after organ transplant to prevent rejection (Ex. cyclosporin, tacrolimus)

Overdosage:

If you or anyone else accidentally take too much of GRAVITOR 60MG, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are muscle or stomach cramps, diarrhea, nausea, vomiting, increased saliva, pin-point pupils of the eyes, sweating, muscle twitching, weakness and slow heartbeat.

SYNOPSIS

Drug :   Pyridostigmine
Pharmacological Category :   Anticholinesterase Drug
Therapeutic Indication :   Myasthenia gravis, Paralytic ileus, Urinary retention after surgery
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep GRAVITOR 60MG out of reach of children
  • Store below 25°C

FAQs ABOUT GRAVITOR 60MG

Can GRAVITOR 60MG be taken during pregnancy?

GRAVITOR 60MG should be used in pregnancy only if considered necessary by your doctor. If you are pregnant, think you may be pregnant or planning to get pregnant, consult your doctor before taking this medicine. Inform your doctor immediately if you become pregnant during treatment with GRAVITOR 60MG.

What is the best time to take GRAVITOR 60MG?

Take GRAVITOR 60MG as advised by your physician. Swallow the medicine with a glass of water. GRAVITOR 60MG is usually taken during the day when maximum strength is required, for example, after getting up and 30 to 60 minutes before having a meal. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Can I take GRAVITOR 60MG if I am constipated?

GRAVITOR 60MG is not recommended for use in patients having constipation or an obstructed digestive tract unless your doctor finds it necessary. Consult your doctor before taking it.

Can GRAVITOR 60MG be given to elderly patients?

GRAVITOR 60MG should be used with caution in elderly patients (aged above 65 years) with irregular heartbeat or other heart condition. Consult your doctor before taking it.

Can I take other medicines with GRAVITOR 60MG?

Before taking GRAVITOR 60MG, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription or any herbal medicine. This is important because taking multiple medicines at a time can strengthen or weaken the effect of the medicines.

Can I drive a car after taking GRAVITOR 60MG?

Do not drive a car or use machinery during GRAVITOR 60MG treatment unless you are sure that your judgement and coordination is not affected, as the effects of this medicine on driving ability is not yet established. Consult your doctor if you feel any side effect during treatment with GRAVITOR 60MG that may stop you from driving or using machines.

What if I forget to take a dose of GRAVITOR 60MG?

If you forget to take a dose of GRAVITOR 60MG, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take the medicine twice to make up for a forgotten dose.

Can I stop taking GRAVITOR 60MG on my own?

Continue taking GRAVITOR 60MG until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. In such case, contact your doctor right away.

Can GRAVITOR 60MG cause vomiting?

Vomiting is a common side effect of GRAVITOR 60MG. In such case, get adequate rest and drink sufficient fluids, especially water. Have small sips if you feel sick. Eat when you feel hungry or when to like to eat, in smaller quantities. Avoid eating oily or fried foods. Do not take any medicine for vomiting without asking your doctor. Tell your doctor if you have continuous vomiting.

What precautions do I need to follow while taking GRAVITOR 60MG?

Patients taking GRAVITOR 60MG must inform their doctor about their pre-existing disease conditions like obstructed digestive or urinary tract, kidney, heart, or thyroid problems, stomach ulcer, fits or parkinson’s disease. Patients should also inform if they are pregnant, breast-feeding or having any allergies. Contact your doctor immediately if you have any unusual symptoms.

REFERENCES

1. Tilo Grosser, Emer Smyth and Garret A. FitzGerald. Anticholinergic Agents. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 213.

2. Maggi, L., & Mantegazza, R. Treatment of myasthenia gravis. SpringerLink. August 2012. [Accessed on 2nd July 2022] https://link.springer.com/article/10.2165/11593300-000000000-00000

3. University of Aarhus. Effect of Pyridostigmine (Mestonin) on Muscle Strength in myasthenia Gravis. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in April 2018] [Accessed on 2nd July 2022] https://clinicaltrials.gov/ct2/show/NCT03510546

4. Labiana Pharmaceuticals S.L.U. Health Products Regulatory Authority (HPRA). [Revised in December 2019] [Accessed on 2nd July 2022] http://www.hpra.ie/img/uploaded/swedocuments/8f7764b6-2c82-4549-a422-d6f5b3a65819.pdf

5. Actavis Group PTC ehf. Pyridostigmine. [Revised in March 2022] [Accessed on 2nd July 2022] https://products.tevauk.com/mediafile/id/52098.pdf

6. Bausch Health Companies Inc. Pyridostigmine. [Revised in December 2020] [Accessed on 2nd July 2022] https://pi.bauschhealth.com/globalassets/BHC/PI/Mestinon-PI.pdf

7. iNova Pharmaceuticals (Australia) Pty Limited. Pyridostigmine. [Revised in March 2021] [Accessed on 2nd July 2022] https://www.nps.org.au/assets/medicines/3b41b44e-e983-4793-8d1e-a53300ff254a.pdf

USEFUL DIAGNOSTIC TESTS

  • Edrophonium test
  • Electromyography (EMG)
  • CT-scan
  • MRI Scan

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    PYRIDOSTIGMINE 60MG
    Hsn Code
    30049099
ALTERNATE BRANDS
Distinon 60mg Tablet 10'S
Prescription Myasthenia Gravis Rx required
Rs.112.11
DISCLAIMER

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Gravitor Tablet 10'S

Gravitor Tablet 10'S Mkt: Sun Pharmaceutical Industries Ltd

M.R.P.: Rs.206.00
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