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GLYMADA 10 M Tablet 10's

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Diabetes Rx required
Dapagliflozin 10 mg+Metformin 500 mg
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MRP ₹108.00
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*10 Tablet(s) in a Strip * Mkt: Europa Healthcare Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

INTRODUCTION

GLYMADA 10 M TABLET is a combination of Dapagliflozin and Metformin which belongs to the group of medicines called Antidiabetics. It is used to treat type-2 diabetes mellitus along with diet and exercise when diabetes cannot be controlled with other medicines. It is also used in combination with insulin or GLP-1 receptor agonist like liraglutide.

Prior to the treatment, your doctor may want you to take several blood tests to understand your existing kidney condition. Avoid consumption of alcohol while taking GLYMADA 10 M TABLET as it may increases the risk of lactic acidosis.

GLYMADA 10 M TABLET is not recommended for use in patients with liver disease, moderate to severe kidney disease, recent heart attack or acute myocardial infarction, heart failure, cardiovascular collapse (shock), septicaemia or severe infection, diabetic ketoacidosis, hypoxemia, diabetic coma or uncontrolled diabetes. Contact your doctor before taking the medicine.

GLYMADA 10 M TABLET is generally not recommended for use in second and third trimester of pregnancy unless considered clearly necessary. Contact your doctor before taking. GLYMADA 10 M TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Contact your doctor before taking.

GLYMADA 10 M TABLET is not recommended for use in children and adolescents under 18 years of age. Contact your doctor before taking. GLYMADA 10 M TABLET should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before taking the medicine. The most common side effects of this medicine are nausea, vomiting, diarrhoea, stomach pain and loss of appetite. Contact your physician if any of the symptoms worsen.

USES OF GLYMADA 10 M TABLET

  • Used to treat type-2 diabetes mellitus

HOW GLYMADA 10 M TABLET WORKS

GLYMADA 10 M TABLET helps to lowers blood glucose levels, where Dapagliflozin works by removing excess sugar from the body in the form of urine and Metformin works by inhibiting glucose production in the liver.

DIRECTIONS FOR USE

Take this medicine as advised by your physician. Swallow this medicine as whole with a glass of water and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF GLYMADA 10 M TABLET

COMMON

  • nausea, vomiting
  • diarrhoea
  • stomach pain
  • loss of appetite
  • genital infection (irritation, itching, unusual discharge, or odour)
  • runny nose, sore throat
  • back pain
  • discomfort when passing urine
  • increased urination
  • changes in cholesterol or fat levels in blood
  • increased red blood cells
  • decrease in creatinine clearance
  • changes in taste
  • dizziness
  • rash

UNCOMMON

  • thirst
  • constipation
  • dry mouth
  • decreased weight
  • elevated creatinine or urea levels

RARE

Stop taking GLYMADA 10 M TABLET and contact your physician immediately if you experience any of the following side effects:

  • nausea, vomiting, stomach pain, muscle cramp, feeling of not being well with severe tiredness, body pains, increasing somnolence, difficulty in breathing, dizziness, light headedness, reduced body temperature, heartbeat, and low blood pressure (symptoms of lactic acidosis)
  • dehydration, nausea, vomiting, abdominal pain, excessive thirst, generalised weakness, rapid weight loss, fast and deep breathing, confusion, unusual sleepiness or tiredness, fruity smell breath, a sweet or metallic taste in mouth, different odour to your urine or sweat (signs and symptoms of diabetic ketoacidosis)
  • symptoms of necrotising fasciitis of the perineum or Fournier’s gangrene such as pain, tenderness, redness, or swelling of the genitals and the anus with fever or feeling generally unwell
  • signs of dehydration such as very dry or sticky mouth, feeling very thirsty, sleepy or tiredness, passing little or no urine, fast heartrate, dizziness, faintness, light-headedness, or weakness when standing up  
  • fever, chills, burning sensation while passing urine, back pain, or blood in urine (signs of urinary tract infection)
  • weakness, shaking, sweating, drowsiness, dizziness, feeling very anxious, fast heartbeat, hunger, headache, change in vision, change in mood or confusion, and irritability (signs of low blood sugar)
  • skin rash, raised red patches on skin, swelling of the face, lips, tongue, and throat causing difficulty in breathing or swallowing (symptoms of serious allergic reactions)

HOW TO MANAGE SIDE EFFECTS

Constipation

Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals and drink water. Exercise regularly. Contact your doctor if constipation did not improve.

Diarrhea

Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for treating diarrhoea. Contact your doctor if diarrhoea did not improve.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not consume alcohol, as it increase dizziness. Contact your doctor if dizziness did not improve.

Headache

Rest and relax. Drink plenty of fluids such as water and apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if headache worsens.

Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Contact your doctor if nausea and vomiting did not improve.

Stomach Pain

Try to rest and relax. Eat small meals but take frequently. Keep a heat pad on your stomach. Contact your doctor if stomach pain worsens.

WARNING & PRECAUTIONS

PREGNANCY
Monitoring required

GLYMADA 10 M TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Contact your doctor before taking.

BREASTFEEDING
Consult your doctor

It is not known whether GLYMADA 10 M TABLET pass through the breast milk, contact your doctor before taking the medicine.

DRIVING AND USING MACHINES
Use with Caution

Do not drive or operate any machines if you experience symptoms of hypoglycaemia such as weakness, dizziness, increased sweating, fast heartbeat, change in vision, difficulty in concentration, weakness, sleepiness, light-headedness after taking GLYMADA 10 M TABLET.

ALCOHOL
Consult your doctor

Avoid consumption of alcohol while taking GLYMADA 10 M TABLET as it increases the risk of lactic acidosis.

KIDNEY
Consult your doctor

GLYMADA 10 M TABLET is not recommended for use in patients with moderate to severe kidney disease and should be used with caution in patients with acute kidney injury. Contact your doctor before taking this medicine.

LIVER
Use with Caution

GLYMADA 10 M TABLET should be used with caution in patients with liver disease. Contact your doctor before taking GLYMADA 10 M TABLET.

ALLERGY
Contraindicated

Do not take GLYMADA 10 M TABLET if you are allergic to Dapagliflozin, Metformin or to any other ingredients of this medicine.

HEART DISEASE
Consult your doctor

GLYMADA 10 M TABLET is not recommended for use in patients with recent heart attack or acute myocardial infarction, heart failure, cardiovascular collapse (shock). It should be used with caution in patients with hypotension. Contact your doctor before taking the medicine.

OTHERS

GLYMADA 10 M TABLET is not recommended for use if you had or have:

  • septicaemia or severe infection
  • diabetic ketoacidosis or type 1 diabetes
  • dehydration from diarrhoea, vomiting and excessive heat exposure
  • diabetic coma
  • uncontrolled diabetes
  • lactic acidosis

Before taking GLYMADA 10 M TABLET, inform your doctor if you:

  • have to undergo intravascular radiocontrast study with iodinated materials for X-ray procedure
  • had any surgical procedure
  • have acute febrile illness
  • are reduced intake of food
  • had prolonged fasting due to acute illness or post-surgery
  • have pancreatic diseases
  • have urinary tract infections
  • have low blood sugar
  • are debilitated, or malnourished
  • have adrenal or pituitary insufficiency
  • have vitamin b12 deficiency
  • have genital mycotic infections
  • have or had bladder cancer
  • have serious illness
  • are on low salt diet
  • had stroke

Use in Pediatrics:

It is not known whether GLYMADA 10 M TABLET is safe and effective in children and adolescents below 18 years of age. Contact your doctor before taking.

Use in Geriatrics:

GLYMADA 10 M TABLET should be used with caution in elderly patients (aged above 65 years). Contact your doctor before taking.

INTERACTIONS

A. Drug-Drug interactions:

Before taking GLYMADA 10 M TABLET inform your doctor if you are taking any of the following medicine:

  • medicines used to treat diabetes mellitus (Ex. glyburide, metformin, pioglitazone, sitagliptin, glimepiride, voglibose and insulin)
  • medicines used to treat high blood pressure and heart diseases (Ex. furosemide, nifedipine, propranolol, enalapril, hydrochlorothiazide, bumetanide, valsartan, digoxin, ranolazine)
  • warfarin (medicines used to treat blood clots)
  • simvastatin (medicines used to treat high cholesterol levels)
  • isoniazid, rifampin (medicines used to treat or prevent tuberculosis)
  • ibuprofen, mefenamic acid (medicines used to treat pain)
  • cimetidine (medicines used to treat gastric ulcers)
  • phenytoin or phenobarbital (medicines used to treat fits)
  • ritonavir, dolutegravir (medicines used to treat HIV infections)
  • salbutamol (medicines used to treat asthma, breathing problems)
  • vandetanib (medicines used for thyroid cancer)
  • acetazolamide, zonisamide, or dichlorphenamide (medicines used to treat glaucoma, heart failure, epilepsy)
  • betamethasone, dexamethasone (medicines used to treat inflammation)
  • fluphenazine (medicines used to treat schizophrenia)
  • levothyroxine (medicines used to treat hypothyroidism)
  • oestrogens, oral contraceptives (Ex. levonorgestrel) medicines used to prevent pregnancy
  • nicotinic acid (vitamin supplements)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdose are hypoglycaemia and lactic acidosis.

SYNOPSIS

Drug :   Dapagliflozin, Metformin
Pharmacological Category :   Antidiabetics
Therapeutic Indication :   Type-2 Diabetes mellitus
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep GLYMADA 10 M TABLET out of reach of children
  • Store at room temperature

FAQs ABOUT GLYMADA 10 M TABLET

Q: What GLYMADA 10 M TABLET used for?

A: It is used to treat type-2 diabetes mellitus along with diet and exercise when diabetes cannot be controlled with other medicines. It is also used in combination with insulin or GLP-1 receptor agonist like liraglutide.

Q: Who should not take GLYMADA 10 M TABLET?

A: GLYMADA 10 M TABLET is not recommended for use in patients with allergic history to dapagliflozin, metformin, liver disease, moderate to severe kidney disease, recent heart attack or acute myocardial infarction, heart failure, cardiovascular collapse (shock), septicaemia or severe infection, diabetic ketoacidosis dehydration, hypoxemia, diabetic coma, uncontrolled diabetes, and lactic acidosis.

Q: Can I take alcohol while taking GLYMADA 10 M TABLET?

A: No. Avoid consumption of alcohol while taking GLYMADA 10 M TABLET as it may increases the risk of lactic acidosis.

Q: How does GLYMADA 10 M TABLET work?

A: It contains two antidiabetic medicines metformin and dapagliflozin which lower the blood sugar levels in type 2 diabetes mellitus by eliminating excess sugars through urine and also by increasing the activity of insulin.

Q: Can I use GLYMADA 10 M TABLET with other diabetic medications?

A: Your doctor may advise GLYMADA 10 M TABLET with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to achieve the controlled blood sugar levels while using this medicine with or without other antidiabetic medications.

Q: Does GLYMADA 10 M TABLET cause low blood sugar?

A: Yes. GLYMADA 10 M TABLET may cause low blood sugar. Stop taking GLYMADA 10 M TABLET and contact your doctor if you experience any unusual symptoms like weakness, shaking, sweating, drowsiness, dizziness, feeling very anxious, fast heartbeat, hunger, headache, change in vision, change in mood or confusion, and irritability. Consult your doctor for advice.

REFERENCES

1. K.D. Tripathi. Insulin, oral hypoglycaemic drugs and glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page - 278, 275.

2. Clifford J Bailey, Jorge L Gross, Delphine Hennicken, Nayyar Iqbal, Traci A Mansfield, James F List. Uses of metformin and dapagliflozin. Biomed Central (BMC). February 2013. [Accessed on 27th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606470/

3. AstraZeneca UK Ltd. Electronic Medicines Compendium (EMC). [Revised in May 2021] [Accessed on 27th June 2022] https://www.medicines.org.uk/emc/files/pil.5293.pdf

4. AstraZeneca Pharmaceuticals. U.S. Food & Drug Administration. [Revised in July 2017] [Accessed on 27th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/205649s008lbl.pdf

5. Torrent Pharmaceuticals Ltd. Dapagliflozin and Metformin. [Revised in May 2022] [Accessed on 27th June 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/3008.pdf

6. AstraZeneca Pharmaceuticals LP. Dapagliflozin and Metformin. [Revised in April 2022] [Accessed on 27th June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ac8a0f7b-9f69-4495-abbc-3a47cd75a859

USEFUL DIAGNOSTIC TESTS

  • Blood glucose levels
  • LDL cholesterol
  • HbA1c
  • Kidney function test

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 03 Feb 2023 | 04:25 PM(IST)

PRODUCT DETAILS

    Net Qty
    1 N
    Shelf Life
    24
    Item Weight
    17.5 g
    Ingredient
    Dapagliflozin 10 mg+Metformin 500 mg
    Hsn Code
    30049099
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.