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GLYDAY MET 1000 Tablet 10's

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Diabetes Rx required
Metformin 1000 mg+Vildagliptin 50 mg
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*10 Tablet(s) in a Strip * Mkt: Elsker Lifescience * Country of Origin: India * Delivery charges if applicable will be applied at checkout

INTRODUCTION

GLYDAY MET 1000 TABLET is a combination of Metformin and Vildagliptin which belongs to a group of medicines called Antidiabetic agents. GLYDAY MET 1000 TABLET is used to treat type 2 diabetes (also known as non-insulin dependent diabetes mellitus) in adult patients, whose diabetes cannot be controlled by diet and exercise alone and/or with other medicines used to treat diabetes (insulin or sulphonylureas such as glimepiride, glipizide). Type 2 diabetes is a chronic medical condition in which the body does not make enough insulin, or the produced insulin does not work well. Symptoms include excessive urination, excessive thirst, hunger, fatigue, and blurred vision.

Metformin decreases hepatic glucose production and intestinal absorption of glucose and improves insulin sensitivity (increases peripheral glucose uptake and utilization). Vildagliptin works by making the pancreas produce more insulin and less glucagon, thus leading to a decrease in blood glucose levels.  Along treatment with GLYDAY MET 1000 TABLET, follow regular exercise and diet plan as advised by your doctor to achieve better results.

Before taking GLYDAY MET 1000 TABLET inform your doctor if you have liver, kidney, or heart problems. It should be used during pregnancy only if advised by your doctor and not recommended for use in breast-feeding women. GLYDAY MET 1000 TABLET is not suitable for use in children and adolescents under 18 years of age and it should be used with caution in elderly patients (65 years of age and above). Avoid consumption of alcohol during treatment with GLYDAY MET 1000 TABLET as it may increase the risk of lactic acidosis. The most common side effects of taking GLYDAY MET 1000 TABLET are nausea, vomiting, stomach pain, headache, low blood sugar and diarrhoea. Contact your doctor if any of the symptoms worsen.

USES OF GLYDAY MET 1000 TABLET

  • To treat type II diabetes mellitus (whose diabetes cannot be controlled by diet and exercise alone and/or with other medicines used to treat diabetes)

HOW GLYDAY MET 1000 TABLET WORKS

GLYDAY MET 1000 TABLET helps to control the level of sugar in the blood, where metformin works by helping the body to make better use of insulin and vildagliptin works by making the pancreas produce more insulin and less glucagon.

DIRECTIONS FOR USE

Always take GLYDAY MET 1000 TABLET as directed by your physician. Take this medicine with or just after the food, swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon age and health condition. Do not stop taking GLYDAY MET 1000 TABLET without informing your doctor.    

SIDE EFFECTS OF GLYDAY MET 1000 TABLET

COMMON

  • nausea
  • vomiting
  • diarrhoea
  • stomach pain
  • loss of appetite
  • dizziness
  • headache
  • metallic taste
  • low blood glucose
  • uncontrolled trembling

UNCOMMON

  • joint pain, tiredness
  • constipation
  • swollen hands, ankle, or feet (oedema)

RARE

Stop taking GLYDAY MET 1000 TABLET and contact your doctor immediately if you experience any of the following side effects:  

  • symptoms of lactic acidosis (such as vomiting, stomach pain, decreased heartbeat, difficulty in breathing, muscle cramps, general weakness with severe tiredness or reduced body temperature)
  • signs of inflamed pancreas (severe and persistent pain in the abdomen with or without nausea or vomiting)
  • signs of liver disease like hepatitis (such as yellowing of skin and eyes, nausea, loss of appetite or dark-colored urine)
  • severe allergic reactions called angioedema (such as swelling of the face, lips, mouth, tongue, or throat that may lead to difficulty in breathing or swallowing)
  • condition that may be associated with dehydration such as severe vomiting, diarrhoea, fever, exposure to heat or if you drink less fluid than normal

HOW TO MANAGE SIDE EFFECTS

Constipation

Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain cereals, and drink plenty of fluids. Exercise more regularly and stay active. Consult your doctor if the symptom did not improve.

Diarrhea

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.

Headache

Rest and relax. Drink sufficient amount of fluids such as water. Apply a pain-relieving balm on the head if required. Consult your doctor if the symptom did not improve.

Nausea And Vomiting

Stick to simple meals. Avoid eating oily, fried, or spicy food. Do not perform any strenuous activities immediately after eating. Consult your doctor if the symptom did not improve.

Stomach Pain

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve on its own.

WARNING & PRECAUTIONS

PREGNANCY
Monitoring required

GLYDAY MET 1000 TABLET is generally not recommended for use in pregnant women unless it is considered clearly necessary. Consult your doctor before taking GLYDAY MET 1000 TABLET.

BREASTFEEDING
Contraindicated

GLYDAY MET 1000 TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking GLYDAY MET 1000 TABLET.  

DRIVING AND USING MACHINES
Use with Caution

Do not drive or operate any machines if you experience dizziness after taking GLYDAY MET 1000 TABLET.      

ALCOHOL
Contraindicated

Consumption of alcohol is not recommended during treatment with GLYDAY MET 1000 TABLET since it may increase the risk of lactic acidosis.

KIDNEY
Contraindicated

GLYDAY MET 1000 TABLET is not recommended in patients with severely reduced kidney function. Consult your doctor before taking GLYDAY MET 1000 TABLET.   

LIVER
Contraindicated

GLYDAY MET 1000 TABLET is not recommended in patients with liver disease. Consult your doctor before taking GLYDAY MET 1000 TABLET.

ALLERGY
Contraindicated

Do not take GLYDAY MET 1000 TABLET if you are allergic (hypersensitive) to Metformin or Vildagliptin.

HEART DISEASE
Contraindicated

GLYDAY MET 1000 TABLET is not recommended in patients who recently had heart attack or heart failure or any signs of heart problems such as serious problems with blood circulation or difficulty in breathing. Consult your doctor before taking GLYDAY MET 1000 TABLET.

USE IN PEDIATRICS
Contraindicated

GLYDAY MET 1000 TABLET is not recommended for use in children and adolescents less than 18 years of age due to lack of safety and effectiveness. Consult with your doctor for advice.

USE IN GERIATRICS
Use with Caution

GLYDAY MET 1000 TABLET should be used with caution in elderly patients above 65 years of age, especially in patients with impaired kidney function. Your doctor will adjust the dose depending upon kidney function and your kidney function will be monitored regularly. Consult with your doctor before taking GLYDAY MET 1000 TABLET.

OTHERS

GLYDAY MET 1000 TABLET is not recommended for you, if you have:

  • type 1 diabetes mellitus
  • uncontrolled diabetes (with severe low blood sugar levels, nausea, vomiting, diarrhoea, rapid weight loss, ketoacidosis, or lactic acidosis)
  • severe infection or seriously dehydrated
  • are going to have a contrast x-ray (a specific type of x-ray involving an injectable dye)

Before taking GLYDAY MET 1000 TABLET, inform your doctor if you have or had:

  • disease of the pancreas
  • going to undergo any surgery
  • vitamin B12 deficiency
  • malnutrition with adrenal or pituitary insufficiency

INTERACTIONS

A. Drug-Drug interactions:

Before taking GLYDAY MET 1000 TABLET inform to your doctor, if you are taking any of these medicines:

  • glucocorticoids such as dexamethasone, prednisolone (treats inflammation)
  • beta-2 agonists such as albuterol, terbutaline (treats respiratory disorders)
  • diuretics such as chlorthalidone, hydrochlorothiazide (used to increase urine production)
  • ibuprofen and celecoxib (treats pain and inflammation)
  • angiotensin-converting enzyme (ACE) inhibitors (Ex. enalapril, lisinopril) and angiotensin II receptor antagonists (Ex. losartan, telmisartan) (treats high blood pressure)
  • medicines affecting the nervous system and thyroid
  • other medicines used to treat diabetes (Ex. glimepiride, glipizide)
  • ranolazine (treats chest pain)
  • dolutegravir (treats HIV infection)
  • vandetanib (treats medullary thyroid cancer)
  • cimetidine (treats heartburn and peptic ulcers)

Overdosage:

If you or anyone else accidentally take too much of GLYDAY MET 1000 TABLET, consult your doctor immediately. Overdosage symptoms of GLYDAY MET 1000 TABLET might include low blood sugar levels, lactic acidosis, muscle pain, mild and transient burning or tickling sensation in body, fever, and edema.

SYNOPSIS

Drug :   Metformin and Vildagliptin
Pharmacological Category :   Antidiabetic agent (Biguanides & Dipeptidyl Peptidase 4 Inhibitor)                                             
Therapeutic Indication :   Type 2 Diabetes mellitus
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep GLYDAY MET 1000 TABLET out of reach of children
  • Do not store above 30°C

FAQs ABOUT GLYDAY MET 1000 TABLET

Q: What is GLYDAY MET 1000 TABLET used for?

A: GLYDAY MET 1000 TABLET is used to treat type 2 diabetes (also known as non-insulin dependent diabetes mellitus) in adult patients, whose diabetes cannot be controlled by diet and exercise alone and/or with other medicines used to treat diabetes (insulin or sulphonylureas such as glimepiride, glipizide).

Q: Can GLYDAY MET 1000 TABLET be used in elderly patients?

A: GLYDAY MET 1000 TABLET should be used with caution in elderly patients above 65 years of age, especially in patients with impaired kidney function. Your doctor will adjust the dose depending upon kidney function and your kidney function will be monitored regularly. Consult with your doctor before taking GLYDAY MET 1000 TABLET. 

Q: Is GLYDAY MET 1000 TABLET safe to use in patients with heart problems?

A: GLYDAY MET 1000 TABLET is not recommended in patients who recently had heart attack or heart failure or any signs of heart problems such as serious problems with blood circulation or difficulty in breathing. Consult your doctor before taking GLYDAY MET 1000 TABLET.

Q: What are the most common side effects of taking GLYDAY MET 1000 TABLET?

A: The most common side effects of taking GLYDAY MET 1000 TABLET are nausea, vomiting, stomach pain, headache, dizziness, loss of appetite, metallic taste, uncontrolled trembling, low blood sugar and diarrhoea. Contact your doctor if any of the symptoms worsen.

Q: Can I consume alcohol while taking GLYDAY MET 1000 TABLET?

A: Consumption of alcohol is not recommended during treatment with GLYDAY MET 1000 TABLET since it may increase the risk of lactic acidosis. Consult your doctor before taking GLYDAY MET 1000 TABLET if you are alcoholic or with history of alcoholism.

REFERENCES

1. KD Tripathi MD. Hormones and related drugs. Essentials of Medical Pharmacology. Seventh edition. New Delhi, May 2013. Page – 274.

2. Paresh Ved and Samrat Shah. Evaluation of vildagliptin and fixed dose combination of vildagliptin and metformin on glycemic control and insulin dose over 3 months in patients with type 2 diabetes mellitus. March 2012. [Accessed on 30th June 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354946/

3. Serge Halimi, Anja Schweizer, Biljana Minic, James Foley and Sylvie Dejage. Combination treatment in the management of type 2 diabetes: focus on vildagliptin and metformin as a single tablet. March 2008. [Accessed on 30th June 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515409/

4. Novartis Pharma GmbH. Electronic Medicines Compendium (EMC) [Revised in August 2021] [Accessed on 30th June 2021] https://www.medicines.org.uk/emc/files/pil.6226.pdf

5. Cipla Ltd. VYSOV-M Tablets (Vildagliptin + Metformin hydrochloride). [Revised in July 2020] [Accessed on June 30, 2021] https://ciplamed.com/print-product-pdf/37162

USEFUL DIAGNOSTIC TESTS

  • Glucose-Fasting Blood
  • Glucose-Postprandial Blood
  • Glycosylated Hemoglobin

AUTHOR DETAILS

Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 28 Feb 2023 | 09:49 AM(IST)

PRODUCT DETAILS
    Net Qty
    1 N
    Shelf Life
    720
    Item Weight
    17.5 g
    Ingredient
    Metformin 1000 mg+Vildagliptin 50 mg
    Hsn Code
    30049099
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.