Glimet Tablet 10'S

Diabetes Rx required

Best Price* ₹ 5.40 MRP ₹ 6.75
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Franco Indian Pharmaceuticals Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

GLIMET TABLET is a combination of Glipizide and Metformin which belongs to the group of medicines called Antidiabetic agents. It is used in adults to treat type II diabetes mellitus when diet, exercise and treatment with single agents does not result in adequate sugar control.

Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin.

Before taking GLIMET TABLET, inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any hormonal imbalance, alcoholism, or if you are malnourished, starved, on an irregular diet as a precaution.

GLIMET TABLET is strictly not recommended for use in patients with type I diabetes mellitus, severe heart failure or lactic acidosis. It is also not suitable for use in pregnant or breastfeeding women.

Along with the treatment, follow the diet and lifestyle changes advised by your doctor to achieve better results. Avoid smoking and consumption of alcohol while taking GLIMET TABLET as it may aggravate your existing condition.

The most common side effects of taking GLIMET TABLET are low blood sugar levels, nausea, vomiting, diarrhea, stomach upset and changes in taste. Consult your doctor if any of these side effect worsens.

USES OF GLIMET TABLET

  • Treats Type II diabetes mellitus

HOW GLIMET TABLET WORKS

GLIMET TABLET stimulates the pancreas to secrete more insulin (a hormone involved in glucose metabolism). It also makes our body more sensitive to insulin which helps in digesting the circulating sugars (glucose) in the blood, thereby reducing blood sugar levels. Additionally, it can also reduce the amount of glucose produced by the liver and reduces its absoprtion in the body.

DIRECTIONS FOR USE

Take GLIMET TABLET preferably 30 minutes before meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Do not stop taking GLIMET TABLET unless your doctor advice you to stop.

SIDE EFFECTS OF GLIMET TABLET

COMMON

  • hypoglycemia (low blood sugar levels)
  • nausea, vomiting
  • diarrhea, stomach pain, loss of appetite
  • changes in taste, metallic taste

UNCOMMON

  • dizziness,  drowsiness
  • feeling shaky
  • blurred vision
  • eczema (skin inflammation)

 

RARE

Stop taking GLIMET TABLET and contact your doctor immediately if you experience any of the following side effects:

  • severe allergic reaction (such as skin rash, swelling of the face, eyelids, lips, tongue, or throat which causes difficulty in breathing or swallowing)
  • signs of severe decrease in blood sugar level (such as confusion, headache, excessive sweating, clammy skin, trembling, weakness, double vision, excessive hunger, nausea, vomiting, problems in sleeping, feeling agitated, unable to concentrate, drowsiness, loss of consciousness, slowed reactions, depression, trouble seeing or speaking, paralysis, numbness, dizziness, hallucinations, difficulty in breathing, slowed or faster heartbeat with chest pain)
  • signs of liver problems (such as nausea or vomiting, stomach pain, unusual or unexplained tiredness, loss of appetite, dark urine, yellowing of the skin or the whites of the eyes)
  • signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)

HOW TO MANAGE SIDE EFFECTS

Hypoglycemia:

Have foods rich in sugars such as fruit juices, glucose drinks, candies, honey or biscuits. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or a drink and check the blood sugar again. Consult your doctor if there is no improvement in your condition.

Diarrhoea:

Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. Do not self-treat diarrhea on your own. Consult your doctor if your diarrhea becomes uncontrollable.

Nausea:

Take GLIMET TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if your nausea worsens.

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol. Consult your doctor if your dizziness worsens.

WARNING & PRECAUTIONS

PREGNANCY

GLIMET TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.

BREASTFEEDING

GLIMET TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any heavy tools or machines if your ability is affected by GLIMET TABLET.

ALCOHOL

Avoid consumption of alcohol while taking GLIMET TABLET as it may increase the risk of unwanted side effects.

KIDNEY

GLIMET TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before taking it.

LIVER

GLIMET TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.

ALLERGY

Do not take GLIMET TABLET if you are allergic to Glipizide, Metformin or to any other sulfonylureas (Ex. glyburide, glimepiride) or sulphonamides (Ex. sulfasalazine).

LUNGS

GLIMET TABLET is not recommended for use in patients with breathing problems (such as asthma or COPD) or lung infections. Therefore, consult your doctor before taking it.

HEART DISEASE

GLIMET TABLET is not recommended for use in patients with severe heart problems (such as heart failure). It should be used with caution in patients with other heart problems. Therefore, consult your doctor before taking it.

OTHERS

GLIMET TABLET is not recommended for use if you:

  • have type I diabetes mellitus (insulin dependent diabetes)
  • have lactic acidosis (build-up of lactic acid in the body)
  • have diabetic ketoacidosis (a diabetic complication causing episodes of fatigue, nausea, frequent urination and muscular stiffness)
  • have uncontrollable diabetes
  • are an alcoholic
  • are severely dehydrated (due to recent diarrhea or vomiting)
  • have any serious infection
  • have shock or problems in blood circulation

Before taking GLIMET TABLET, inform your doctor if you:

  • have G6PD deficiency
  • are on fating or malnourished, starved, on an irregular diet, or feeling weak
  • perform extreme physical exercises without proper carbohydrate intake
  • have hormonal problems (Ex. disorders of pituitary gland, adrenal cortex or thyroid gland)
  • smoke
  • are scheduled for any X-rays or a major surgery

Use in pediatrics:

GLIMET TABLET is not recommended for use in children and in adolescents (aged below 18 years). Therefore, consult your doctor before taking it.

Use in geriatrics:

GLIMET TABLET should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking GLIMET TABLET, inform your doctor if you are taking any of the following medicines:

  • other medicines used to treat diabetes (Ex. teneligliptin, rosiglitazone, pioglitazone, glimepiride)
  • diuretics (used to reduce edema and to treat hypertension) Ex. furosemide, hydrochlorothiazide
  • medicines used to treat pain and inflammation (such as ibuprofen and celecoxib)
  • medicines used to treat high blood pressure (such as atenolol, propranolol, captopril, enalapril, ramipril, lisinopril, losartan, valsartan, olmesartan, telmisartan)
  • medicines used to treat asthma (Ex. salbutamol or terbutaline)
  • corticosteroids (used to treat pain and inflammation) Ex. hydrocortisone, prednisolone
  • verapamil (a medicine used to treat heart problems)
  • rifampicin (a medicine used to treat tuberculosis)
  • cimetidine (a medicine used to treat stomach ulcer)
  • dolutegravir (a medicine used to treat HIV infection)
  • ranolazine (a medicine used to treat chest pain)
  • trimethoprim (a medicine used to treat bacterial infection)
  • vandetanib, crizotinib and olaparib (medicines used to treat cancer)
  • antifungal medicines (used to treat fungal infections) such as miconazole, isavuconazole or fluconazole
  • antibiotics (used to treat bacterial infections) such as fluorquinolones (Ex. ciprofloxacin, moxifloxacin), clarithromycin, co-trimoxazole, rifampicin, chlormaphenicol, tetracyclines or sulphonamides (Ex. sulphasalazine)
  • medicines used to treat stomach ulcers such as ranitidine, famotidine, cimetidine
  • medicines used to treat depression (such as moclobemide, isocarboxazid, phenelzine and tranylcypromine)
  • medicines used for pain relief (Ex. aspirin, phenylbutazone, ibuprofen, phenylbutazone, azapropazone)
  • medicines to treat mental illness (such as chlorpromazine, prochlorperazine, lithium)
  • danazol (a medicine used to treat breast disorders, heavy menstrual bleeding and endometriosis)
  • medicines used for blood thinning (Ex. warfarin)
  • oral contraceptives (birth control pills) Ex. drospirenone, ethinylestradiol
  • sulfinpyrazone, probenecid (medicines used to treat gout)
  • thyroid hormones such as thyroxine (used to treat thyroid deficiency)
  • phenytoin (a medicine used to treat epilepsy)
  • clofibrate, nicotinic acid (medicines used to treat high blood cholesterol levels)
  • isoniazid (a medicine used to treat tuberculosis)

Overdosage:

If you or anyone else accidentally took more GLIMET TABLET, you may experience the signs of hypoglycemia (such as increased hunger, sweating, headache, feeling clammy, restless or aggressive, shakiness, fast heartbeat and confusion). To manage this, consume any sugary food immediately. If the symptom did not improve or worsens contact your doctor immediately. Other symptoms of overdosage might include vomiting, stomach pain with muscle cramps, feeling generally unwell with severe tiredness and difficulty in breathing.

SYNOPSIS

Drug :   Glipizide, Metformin
Pharmacological Category :   Sulfonylureas, Biguanides
Therapeutic Indication :   Type II diabetes mellitus           
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep GLIMET TABLET out of reach of children
  • Store GLIMET TABLET at room temperature

FAQs ABOUT GLIMET TABLET

Q: What is GLIMET TABLET used for?

A: GLIMET TABLET is an antidiabetic medicine used to treat Type II diabetes mellitus when diet, exercise and treatment with single agents does not result in adequate response.

Q: How and when to take GLIMET TABLET?

A: Take GLIMET TABLET preferably 30 minutes before meals or as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Q: How long should I take GLIMET TABLET?

A: You need to take GLIMET TABLET as long as your doctor or physician prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Q: What is the best time to take GLIMET TABLET?

A: GLIMET TABLET must be taken just before meals to avoid gastrointestinal side effects.

Q: What to do if I forgot to take a dose of GLIMET TABLET?

A: If you forgot to take a dose of GLIMET TABLET, take it as soon as you remember. However, if it is time for the next dose of GLIMET TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of GLIMET TABLET to compensate the missed ones.

Q: Can I stop taking GLIMET TABLET without consulting your doctor?

A: No. You should not stop taking GLIMET TABLET without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using GLIMET TABLET, consult your doctor for advice.

Q: Will taking a higher dose of GLIMET TABLET be more effective?

A: No, taking a higher dose of GLIMET TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.

Q: Can I take medication for high blood pressure along with GLIMET TABLET?

A: It is not advisable to take medicines to control blood pressure while taking GLIMET TABLET without consulting your doctor, as they have known interactions with GLIMET TABLET.

Q: How to manage the side effects of GLIMET TABLET?

A: Low blood sugar is a common side effect of taking GLIMET TABLET. Try to have sugar rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey or sugary candy. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or drink, and check the blood sugar levels once again. If your condition did not improve, consult your doctor immediately.

Q: Can GLIMET TABLET be taken with insulin?

A: Co-administration of GLIMET TABLET with insulin is considered risky as they can increase the chances of hypoglycemia (low blood sugar levels). Therefore, consult your doctor before taking it.

Q: Can GLIMET TABLET be used in pregnant women?

A: GLIMET TABLET is not recommended for use in pregnant women. Therefore, consult your doctor for advice before taking it.

Q: What are the side effects of taking GLIMET TABLET?

A: The most common side effects of taking GLIMET TABLET are low blood sugar levels, nausea, vomiting, diarrhea, stomach upset and changes in taste. Consult your doctor if any of these side effect worsens.

Q: Can GLIMET TABLET cause dizziness?

A: Yes. Dizziness is a common side effect of using GLIMET TABLET. In case you experience dizziness, lie down until it passes, then get up slowly and carefully. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, and alcohol. Do not drive or use machinery to avoid accidents. Consult your doctor if you experience dizziness continuously for a long time after taking GLIMET TABLET.

Q: What precautions do I need to follow while taking GLIMET TABLET?

A: Before taking GLIMET TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any severe systemic infections or are severely dehydrated due to excessive vomiting or diarrhea recently. Along with the therapy, follow the diet and lifestyle changes advised by your doctor to achieve better results. Consult your doctor before taking GLIMET TABLET if you are pregnant or breastfeeding.

REFERENCES

1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 270 & 275.

2. Ricardo Correa; Bryan S. Quintanilla Rodriguez; Thomas M. Nappe. Glipizide. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. July 2022. [Accessed on 17th January 2023] https://www.ncbi.nlm.nih.gov/books/NBK459177/

3. Jie Hong, Yifei Zhang, Shenghan Lai, Ankang Lv, Qing Su, Yan Dong, Zhiguang Zhou, Weili Tang, Jiajun Zhao, Lianqun Cui, Dajin Zou, Dawang Wang, Hong Li, Chao Liu, Guoting Wu, Jie Shen, Dalong Zhu, Weiqing Wang, Weifeng Shen, Guang Ning and on behalf of the SPREAD-DIMCAD Investigators. Effects of Metformin Versus Glipizide on Cardiovascular Outcomes in Patients With Type 2 Diabetes and Coronary Artery Disease. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. April 2013. [Accessed on 17th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631843/

4. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in June 2020] [Accessed on 17th January 2023] https://www.medicines.org.uk/emc/files/pil.594.pdf

5. Rx Farma Limited. Electronic Medicines Compendium (EMC). [Revised in September 2019] [Accessed on 17th January 2023] https://www.medicines.org.uk/emc/files/pil.11951.pdf

6. Pharmacia Italia S.p.a., Ascoli Piceno Plant. MinodiabÒ 5 mg Tablets Glipizide. Electronic Medicines Compendium (EMC). [Revised in February 2018] [Accessed on 17th January 2023] https://www.medicines.org.uk/emc/files/pil.1687.pdf

7. Actavis Pharma, Inc. GLIPIZIDE ER- glipizide tablet, film coated, extended release. Dailymed.com. [Revised in December 2020]. [Accessed on 17th January 2023] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=a430577c-f233-40a7-bfd8-3d2bc6f98aa2

8. Central Drugs Standard Control Organization. Glipizide 2.5mg/5mg +Metformin 250mg/500mg tablet. March 1998. [Accessed on 17th January 2023] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf

USEFUL DIAGNOSTIC TESTS

  • Glucose-Fasting Blood
  • Glucose-Postprandial Blood
  • Glycosylated Haemoglobin

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    GLIPIZIDE 2.5MG+METFORMIN HYDROCHLORIDE 250MG
    Hsn Code
    30043190
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Glimet Tablet 10'S

Glimet Tablet 10'S Mkt: Franco Indian Pharmaceuticals Pvt Ltd

M.R.P.: Rs.6.75
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