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Drug Information

What is Allylestrenol used for?

Allylestrenol, also known as Allyloestrenol and Allyl estrenol, is used in women for prevention of:

  • Threatened miscarriage or abortion;
  • Intra uterine growth retardation (IUGR);
  • Habitual abortion;
  • Threatened premature labour;
  • Failure of nidation (initial formation of embryo).

Allylestrenol is used in men for benign prostatic hyperplasia (non-cancerous increase in the size of prostate).

Allylestrenol may also be prescribed for other conditions as determined by your doctor.

How does Allylestrenol work?

Allylestrenol belongs to a class of medicines known as progesterones. Progesterones are one of the hormones in our body which help to maintain pregnancy. Allylestrenol acts by:

  • Increasing the placental progesterone production;
  • Stimulating syncytiotrophoblast enzymatic activity (helps in implantation);
  • Stimulating production of Endogenous HCG, HPL, placental hormones, and enzymes;
  • Decreasing myometrial sensitivity (prevents contraction of uterus muscles);
  • Increasing utero-placental (between the uterus and placenta) blood flow. 

How to take Allylestrenol?

  • The dosage of oral tablet of Allylestrenol depends on the age, weight and medical condition of an individual. Take Allylestrenol as prescribed by your doctor.
  • Allylestrenol should be taken with or without food. Do not chew or break modified-release tablets, as this will affect the way the medicine inside them is released.
  • Allylestrenol is not advised to be taken by children younger than 16 years of age.
  • Do not discontinue Allylestrenol without consulting a doctor.
  • If you miss a dose of Allylestrenol, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.
  • Allylestrenol is to be used specifically in pregnant women. Allylestrenol should be discontinued after delivery.

What should you do when you have taken an overdose of Allylestrenol?

If you have taken an overdose of Allylestrenol, please contact your doctor immediately.

Symptoms of overdose may include the following:

  • Drowsiness
  • Rapid pulse
  • Fainting
  • Unusual muscle movement or rigidity of the face, neck or limb
  • Seizures
  • Loss of consciousness
  • Nausea

What are the drugs that interact with Allylestrenol?

Drugs that interact with Allylestrenol:

  • Carbamazepine
  • Cyclosporin
  • Griseofulvin, Ketoconazole
  • Phenobarbital
  • Phenytoin
  • Rifampicin

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Allylestrenol?

Most common side effects of Allylestrenol are: 

  • Diarrhoea, weight changes, loss of appetite
  • Oedema
  • Acne, skin rash
  • Urticaria
  • Depression
  • Headache, fever, fatigue
  • Breast changes
  • Hirsutism (excessive hair growth on face)
  • Change in libido
  • Altered menstrual cycle
  • Irregular bleeding

Please stop your tablets and contact your physician immediately if you have

  • vaginal bleeding
  • incomplete abortion
  • sudden, partial or complete loss of vision
  • double vision
  • migraine
  • changes in your liver and kidney function tests

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Allylestrenol?

  • Seek doctor’s advice before taking any other drug or herbal products while on Allylestrenol.
  • Sudden withdrawal of allyloestrenol must be avoided, as it will cause intermittent breakthrough bleeding and lactation.

You are advised not to take Allylestrenol if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Allylestrenol?

Tell your doctor if

  • you are allergic to Allylestrenol or other medicine from the same class.
  • you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • you have thrombophlebitis.
  • you have vaginal bleeding.
  • you have hormone dependent cancer.
  • you have cerebral apoplexy.
  • severe liver dysfunction.
  • you have cardiac or renal dysfunction.
  • you have migraine.
  • you have asthma.
  • you have history of depression.
  • you are diabetic.
  • you have glucose intolerance.
  • you are planning a surgery or any procedure.
  • you are breastfeeding.

Frequently asked questions about Allylestrenol

  1. How should Allylestrenol be stored?
  2. Allylestrenol tablets and oral suspension must be stored in a cool and dry place. Allylestrenol must not be exposed to light and moisture as it becomes less active. Allylestrenol must be kept out of children’s reach.

  3. Should I follow any special dietary instructions while taking Allylestrenol?
  4. No, you can have your normal diet unless advised by your doctor.

  5. Can I drive while taking Allylestrenol?
  6. Allylestrenol causes dizziness and headaches in some individuals. It is advisable not to drive while taking Allylestrenol.

  7. Can I drink alcohol with Allylestrenol?
  8. It is better to avoid alcohol while taking Allylestrenol as the medicine potentiates the effect of alcohol.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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