Genotropin 36Iu Injection 1'S

Blood Clot Rx required
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Best Price* ₹ 12,113.60 MRP ₹ 15,142.00
(Inclusive of all taxes) * Mkt: Pfizer Limited * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

GENOTROPIN 36IU INJECTION contains Somatropin which belongs to the group of medicines called Growth hormone agonists. It is used in children with growth failure due to growth hormone deficiency (GHD), idiopathic short stature (ISS), Turner syndrome (TS), Prader-Willi Syndrome, are too small or light at birth and in chronic kidney disease (CKD).

In adults it is used to treat either childhood-onset or adult-onset GHD. Growth hormone deficiency (GHD) is also called dwarfism or pituitary dwarfism. It is a disease characterized by low growth hormone levels in the body.

Your doctor might want you to take certain tests and follow a particular diet during treatment with GENOTROPIN 36IU INJECTION. GENOTROPIN 36IU INJECTION is not recommended for use if you have an active cancer, are seriously ill (like you need to get a surgery done) or if your growth has already stopped.

Before receiving GENOTROPIN 36IU INJECTION, inform your doctor if you have myalgia, diabetes, kidney or thyroid problem. GENOTROPIN 36IU INJECTION is not recommended for use in pregnant women and caution should be exercised while using it in breastfeeding women.

It should be used with caution in elderly patients above 80 years of age. The most common side effects of receiving GENOTROPIN 36IU INJECTION are joint pain, water retention (which shows as puffy fingers or swollen ankles), injection site reaction. Contact your physician for advice if any of the symptoms worsen.

USES OF GENOTROPIN 36IU INJECTION

Treats:

  • Children with growth failure due to growth hormone deficiency (GHD), idiopathic short stature (ISS), Turner syndrome (TS), Prader-Willi Syndrome and chronic kidney disease (CKD)
  • Children who are too small or light at birth
  • Childhood-onset or adult-onset GHD in adults

HOW GENOTROPIN 36IU INJECTION WORKS

GENOTROPIN 36IU INJECTION is a man-made form of growth hormone which resembles natural human growth hormone that stimulates the production of another growth hormone called insulin-like growth factor 1 or IGF-1. It helps the bones, muscles to grow and develop in the right amount.

DIRECTIONS FOR USE

GENOTROPIN 36IU INJECTION will be given to you only by a doctor or a nurse via subcutaneous injection that is injected into the fatty tissue just under the skin. The correct dose and duration will be decided by your physician for you depending on your age, body weight and disease condition.

SIDE EFFECTS OF GENOTROPIN 36IU INJECTION

COMMON

  • joint pain
  • water retention (which shows as puffy fingers or swollen ankles)
  • injection site reaction (signs include temporary reddening, itchiness or pain)
  • numbness / tingling
  • stiffness in the legs and arms, muscle pain
  • pain or burning feelings in the hands or underarms

UNCOMMON

  • rash/itching
  • breast enlargement (gynecomastia)
  • leukemia
  • increased intracranial pressure (symptoms such as strong headache, visual disturbances or vomiting)
  • muscle pain
  • raised itchy bumps on skin

RARE

Stop receiving GENOTROPIN 36IU INJECTION and contact your doctor immediately if you experience any of the following side effects:

  • walk with a limp or start to limp during the treatment due to pain in the hip
  • developing raised intracranial pressure (with symptoms like strong headache, visual disturbances or vomiting)
  • experience worsening abdominal pain
  • have headaches, changes in behavior, changes in vision, changes in moles, birthmarks or the color of the skin
  • serious allergic reactions (symptoms include swelling of the face, lips, mouth or tongue, trouble breathing, wheezing, severe itching, skin rashes, redness or swelling, dizziness or fainting, fast heartbeat or pounding in the chest and sweating)
  • body holding too much fluid (fluid retention) such as swelling in the hands and feet, pain in the joints or muscles or nerve problems that cause pain, burning or tingling in the hands, arms, legs and feet
  • darkening of the skin, dizziness, weakness, severe fatigue or weight loss
  • worsening of bend of the spine (scoliosis)
  • severe and constant abdominal pain (may be a sign of pancreatitis)

WARNING & PRECAUTIONS

PREGNANCY

GENOTROPIN 36IU INJECTION is not recommended for use in pregnant women and women planning to have a baby as safety data has not been established yet. Consult your doctor before receiving GENOTROPIN 36IU INJECTION.

BREASTFEEDING

GENOTROPIN 36IU INJECTION should be used with caution in breastfeeding women as it is not known whether it passes through the breastmilk. Consult your doctor before receiving GENOTROPIN 36IU INJECTION.

DRIVING AND USING MACHINES

GENOTROPIN 36IU INJECTION does not affect the ability to drive and use machines.

KIDNEY

GENOTROPIN 36IU INJECTION should be used with caution in patients with kidney problems. It should not be used during kidney transplant. Consult your doctor before receiving GENOTROPIN 36IU INJECTION.

ALLERGY

Do not receive GENOTROPIN 36IU INJECTION if you are allergic to somatropin or any other ingredients of this medicine.

HEART DISEASE

GENOTROPIN 36IU INJECTION is not recommended for use in patients with open-heart surgery. Consult your doctor before receiving GENOTROPIN 36IU INJECTION.

OTHERS

GENOTROPIN 36IU INJECTION is not recommended for use if you:

  • are seriously ill (for example, complications following open heart surgery, abdominal surgery, acute respiratory failure, accidental trauma or similar conditions)
  • children with Prader-Willi syndrome who are severely obese
  • have a history of severe upper airway obstruction
  • have active cancer
  • have severe non-proliferative or active proliferative diabetic retinopathy
  • pediatric patients with closed epiphyses
  • if your growth has stopped

Before receiving GENOTROPIN 36IU INJECTION, inform your doctor if you have:

  • myalgia
  • diabetes
  • thyroid problem

Use in Geriatrics:

GENOTROPIN 36IU INJECTION should be used with caution in elderly patients above 80 years of age. Consult your doctor before receiving GENOTROPIN 36IU INJECTION.

INTERACTIONS

A. Drug-Drug interactions:

Before receiving GENOTROPIN 36IU INJECTION, inform your doctor if you are taking any of the following medicine:

  • replacement therapy with glucocorticoids (Ex. prednisone)
  • medicine used to treat diabetes (Ex. glimepiride, metformin)
  • medicine used as thyroid hormones (Ex. thyroxine)
  • synthetic adrenal hormones (corticosteroids)
  • medicines used for contraception (Ex. estrogen is taken orally or other sex hormones)
  • medicine used to weaken the immune system after transplantation (Ex. ciclosporin)
  • medicines used to control epilepsy (anticonvulsants) (Ex. carbamazepine, frisium)
  • cytochrome P450- metabolized drugs (Ex. benzodiazepines, cyclosporine)

Overdosage:

GENOTROPIN 36IU INJECTION will be administered only by a doctor or a nurse in a hospital and so it is unlikely to receive an overdose. However, consult your doctor or nurse if there are any unusual symptoms of hypoglycemia, hyperglycemia, gigantism and/or acromegaly (excess growth hormone).

SYNOPSIS

Drug :   Somatropin
Pharmacological Category :   Growth Hormone Agonists
Therapeutic Indication :   To increase growth
Dosage Forms :   Injection

MORE INFORMATION

  • Keep GENOTROPIN 36IU INJECTION out of reach of children
  • Store in a refrigerator at a temperature of 2°C to 8°C

FAQs ABOUT GENOTROPIN 36IU INJECTION

Q: Is GENOTROPIN 36IU INJECTION safe to use in pregnancy?

A: GENOTROPIN 36IU INJECTION is not recommended for use in pregnancy as safety data has not been established yet. Consult your doctor before receiving GENOTROPIN 36IU INJECTION.

Q: Can GENOTROPIN 36IU INJECTION be used in diabetic patients?

A: Caution should be taken while using GENOTROPIN 36IU INJECTION if you are diabetic. If you have diabetes, constant monitoring of blood sugar levels is required while receiving GENOTROPIN 36IU INJECTION. Discuss with your doctor before receiving GENOTROPIN 36IU INJECTION.

Q: Can I receive GENOTROPIN 36IU INJECTION along with thyroid hormones?

A: Caution to be taken if GENOTROPIN 36IU INJECTION is used along with thyroid hormones because thyroid hormone dose may need to be adjusted. Your physician may adjust the dose of your thyroid hormone accordingly.

Q: How does GENOTROPIN 36IU INJECTION work?

A: GENOTROPIN 36IU INJECTION is a man-made form of growth hormone which resembles natural human growth hormone and is required for the growth of bones and muscles. It also helps the fat and muscle tissues to develop in the correct proportion.

Q: Who should not receive GENOTROPIN 36IU INJECTION?

A: GENOTROPIN 36IU INJECTION is not recommended for use in patients having an acute critical illness, pediatric with Prader-Willi syndrome who are severely obese, have a history of severe upper airway obstruction, active malignancy, severe non-proliferative or active proliferative diabetic retinopathy and in pediatric patients with closed epiphyses. Consult your doctor before receiving GENOTROPIN 36IU INJECTION.

REFERENCES

1. Mark E. Molitch and Bernard P. Schimmer. Introduction to Endocrinology: The Hypothalamic-Pituitary Axis. Goodman & Gilman’s: The Pharmacological basics of Therapeutic, 13th Edition. New York McGraw Hill Medical 2018. Page – 777-778.

2. KD. Tripathi. Anterior Pituitary Hormones. Essentials of medical pharmacology. Seventh edition. 2013. Page – 237.

3. Jens Sandahl Christiansen, Philippe F Backeljauw, Martin Bidlingmaier, Beverly M K Biller, Margaret C S Boguszewski, Felipe F Casanueva, Philippe Chanson, Pierre Chatelain, Catherine S Choong, David R Clemmons and et.al. Growth Hormone Research Society perspective in the development of long-acting growth hormone preparations. NIH National Library of Medicine. National Centre for Biotechnology Information. Pubmed Central. June 2016. [Accessed on 24th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081743/

4. Christina Southern Reh and Mitchell E Geffner. Somatotropin in the treatment of growth hormone deficiency and Turner syndrome in pediatric patients: a review. NIH National Library of Medicine. National Centre for Biotechnology Information. Pubmed Central. June 2010 [Accessed on 24th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262362/

5. Pfizer Manufacturing Belgium NV. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 24th June 2022] https://www.medicines.org.uk/emc/files/pil.3429.pdf, https://www.medicines.org.uk/emc/product/3429/smpc

6. Novo Nordisk A/S. Somatotropin. [Revised in March 2020] [Accessed on 24th June 2022] https://www.novo-pi.com/norditropin.pdf

USEFUL DIAGNOSTIC TESTS

  • Kidney function tests
  • Blood sugar test
  • Thyroid function test

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    20 g
    Ingredient
    SOMATROPIN 36 IU
    Hsn Code
    30049099
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