INTRODUCTION

GB 40MG contains Ginkgo biloba which belongs to the group of medicines called Antidementia agents. It is used in the symptomatic treatment of circulation, dysfunction, and memory loss due to organic brain changes as part of an overall therapeutic concept in patients with a decline in or loss of acquired cognitive skills (dementia) with primary complaints of impaired memory, difficulty concentrating, depressed mood, dizziness, tinnitus, headaches that occurs in conditions such as stroke (brain damage due to interruption of blood supply to the brain) and Alzheimer’s disease (progressive disease that destroys memory and other important mental functions).

Ginkgo biloba works by protecting brain cells from damage due to free radicals, cell death due to aging, and neurodegenerative disorders thus increasing the blood flow to the brain and providing relief from symptoms of dementia, stroke, and Alzheimer’s disease. Prior to treatment, your doctor will check whether the symptoms are not due to an underlying disease that requires specific treatment.

GB 40MG is not recommended for use in patients who are scheduled for surgery. Before taking GB 40MG, inform your doctor if you have a history of bleeding disorders, fits, frequent dizziness and tinnitus (ringing in the ear), liver, and or kidney disease. GB 40MG is not recommended for use in pregnant and breastfeeding women. It is also not recommended for use in children and adolescents (aged less than 18 years). Consult your doctor before taking it. The most common side effect associated with the use of GB 40MG is vascular headache (headache that occurs due to changes in blood vessels in the head or neck). Contact your doctor if this side effect worsens.

USES OF GB 40MG

• Used as symptomatic treatment of circulation, dysfunction, and memory loss due to organic brain changes (in conditions like dementia, stroke and Alzheimer’s disease)

HOW GB 40MG WORKS

GB 40MG works by protecting brain cells from damage due to free radicals, cell death due to aging, and neurodegenerative disorders thus increasing the blood flow to the brain and providing relief from symptoms of dementia, stroke, and Alzheimer’s disease.

DIRECTIONS FOR USE

Take GB 40MG as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF GB 40MG

HOW TO MANAGE SIDE EFFECTS

Headache:

Drink ample amount of water and get adequate rest. Try to be relaxed and stress free. Ask your doctor before taking any medicine for headache. If headache does not improve, contact your doctor.

Dizziness:

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid smoking cigarettes and drinking alcohol. If dizziness does not improve, consult your doctor.

Diarrhea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult your doctor and inform if the symptom gets worse.

Nausea:

Try to take GB 40MG with or just after a meal or a snack. Stick to simple meals. Avoid eating oily, fried or spicy foods. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interaction:

Before taking GB 40MG, inform your doctor if you are taking any of the following:

• anticoagulant medicines (used to prevent blood clots) Ex. phenprocoumon, warfarin, clopidogrel, aspirin
• nonsteroidal anti-inflammatory drugs (NSAIDs) (medicines used to reduce inflammation and relieve pain) Ex. ibuprofen, diclofenac

B. Drug-Food Interaction:

Avoid taking ginkgo fruits/seeds as their interaction may result in toxic effect.

Overdosage:

If you or anyone else accidentally take too much of GB 40MG, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep GB 40MG out of reach of children
• Store at room temperature

FAQs ABOUT GB 40MG

How long does it take for GB 40MG to work?

An individual patient's response to GB 40MG cannot be predicted. Stick to the prescribed schedule for the medicine to work. If there is no improvement in your condition or if your symptoms worsen after taking this medicine for several days, please contact your doctor.

Can GB 40MG be given to children?

No, GB 40MG is not recommended for use in children and adolescents (below 18 years of age). If GB 40MG is accidentally ingested by a child or adolescent, go to the hospital immediately and consult the doctor for further management.

What if I forget to take a dose of GB 40MG?

If you forget to take a dose of GB 40MG, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take the medicine twice to make up for the missed dose.

Can I stop taking GB 40MG on my own?

Continue taking GB 40MG until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. Discontinuing or stopping early may make your condition to get worse or recur.

What precautions do I need to follow while taking GB 40MG?

Patients taking GB 40MG must inform their doctor about their pre-existing conditions like history of bleeding disorders, epilepsy, or any upcoming surgery. Patients should also inform if they are pregnant, breast-feeding, or have any allergies. Consult your doctor if you experience any unusual effect during treatment with this medicine.

Can GB 40MG be taken during pregnancy?

GB 40MG is not recommended for use in pregnant women. If you are pregnant, think you may be pregnant or planning to get pregnant, consult your doctor before taking this medicine. Inform your doctor immediately if you become pregnant during treatment with GB 40MG.

Can I take other medicines with GB 40MG?

Before taking GB 40MG, inform your doctor if you are taking medicines to thin your blood (such as warfarin), relieve pain (such as ibuprofen), or any other medicine, including prescription, non-prescription or any herbal medicine, as these might interact with each other and cause serious side effects.

REFERENCES

1. KD. Tripathi. CNS Stimulants and Cognition Enhancers. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 491.

2. Ho-Sook Kim, Ga-young Kim, Chang-Woo Yeo, Minkyung Oh, Jong-lyul Ghim, Ji-Hong Shon, Eun-Young Kim, Dong-Hyun Kim, and Jae-Gook Shin. The effect of Ginkgo biloba extracts on the pharmacokinetics and pharmacodynamics of cilostazol and its active metabolites in healthy Korean subjects. NIH. National Library of Medicine. National center for biotechnology information. PMC PubMed Central. May 2014. [Accessed on 14th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004402/

3. Hongyun Wang, Meilin Yuan, and Xinrong Zou. Efficacy and safety of Ginkgo biloba for patients with early diabetic nephropathy. NIH. National Library of Medicine. National center for biotechnology information. August 2020. [Accessed on 14th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7458229/

4. Helene Amieva, Celine Meillon, Catherine Helmer, Pascale Barberger-Gateau, and Jean Francois Dartigues. Ginkgo Biloba Extract and Long-Term Cognitive Decline: A 20-Year Follow-Up Population-Based Study. NIH. National Library of Medicine. National center for biotechnology information. PMC PubMed Central. January 2013. [Accessed on 14th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543404/

5. Krewel Meuselbach GmbH. Ginkgo-Maren 120 mg Film-Coated Tablets. [Revised in January 2016] [Accessed on 14th July 2022] https://www.krewelmeuselbach.com/en/pdf/figihwg/Ginkgo-Maren_EN.pdf

6. Taj Pharma. Ginkgo Biloba Tablets 40mg. [Accessed on 14th July 2022] https://tajlifesciences.com/portfolio/ginkgo-biloba-tablets-40mg/