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INTRODUCTION
GATE DM EYE DROPS is a combination of Dexamethasone and Gatifloxacin which belongs to the group of medicines called Corticosteroids and Antibiotics respectively. It is used to treat and prevent eye inflammation and infection.
It also helps in reducing eye pain, redness, itching and/or burning or stinging sensation following eye surgery (such as cataract or corneal refractive surgery). It is typically used in conditions which involves the risk of both eye inflammation and infection such as during injuries or post-surgery.
Use this medicine exactly as instructed by your physician. Misuse or overuse of this medicine may lead to unwanted side effects. If there is no improvement in your condition even after using this medicine for 7 days, consult your doctor for advice.
If you wear soft contact lenses, remove the lens before applying GATE DM EYE DROPS and wait for at least 15 minutes before reinsertion.
Before using GATE DM EYE DROPS inform your doctor if you have severe viral or fungal eye infections. You must also inform your doctor if you have glaucoma or any holes or ulcerations in the eyes as a precaution.
Do not use GATE DM EYE DROPS without consulting your doctor if you are pregnant or breastfeeding. The most common side effects of using GATE DM EYE DROPS are mild eye irritation or burning sensation, watery eyes, increased eye pressure, headache and taste changes. Consult your doctor if any of these side effect worsens.
USES OF GATE DM EYE DROPS
- Treats and prevents eye infection and inflammation
- Reduces eye pain, redness, itching or burning/stinging sensation following eye surgery
HOW GATE DM EYE DROPS WORKS
GATE DM EYE DROPS contains two medicines namely, Dexamethasone and Gatifloxacin. Dexamethasone is a steroid medication. It blocks the release of certain chemicals in the body (such as prostaglandins) that causes inflammation, redness and swelling. When applied topically on the eyes, it reduces eye redness, soreness, pain, itching and swelling.
Gatifloxacin is an antibiotic. When applied topically on the eyes, it kills the susceptible bacteria that causes eye infection. Collectively, this medicine reduces inflammation and infection of the eyes.
DIRECTIONS FOR USE
Use GATE DM EYE DROPS as advised by your physician. It is for ophthalmic use only. Tilt your head slightly backwards and gently pull your lower eyelid. Instil few drops of this medicine into the eyes and close your eyes for 2 minutes. Repeat the same for the other eye if required. If you wear soft contact lenses, remove the lens before applying GATE DM EYE DROPS and wait for at least 15 minutes before reinsertion.
Wash your hands before and after application. Do not touch the tip of the container with your eyes, eyelids, areas around your eyes, outer surface of the ears or fingers, to avoid contamination. Leave a time gap of at least 5 minutes between this medicine and other eye medicines.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. If there is no improvement in your condition even after using this medicine for 7 days, consult your doctor for advice.
SIDE EFFECTS OF GATE DM EYE DROPS
COMMON
- eye pain, itching, irritation or discomfort
- burning sensation in the eyes
- excess watering of eyes
- increased pressure within the eyes (after 2 weeks of use)
UNCOMMON
- dry eyes
- eye redness
- eye surface inflammation
- abnormal eye sensation
- headache
- bad taste
- cloudy lens, blurred vision
RARE
Stop using GATE DM EYE DROPS and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat, tongue causing difficulty in breathing or swallowing)
- severe skin reactions with blistering and peeling of skin
- severe eye pain, redness, irritation and vision changes
HOW TO MANAGE SIDE EFFECTS
Burning sensation in the eyes:
Wash your eyes with plain cold water. Place an ice pack on your eye to ease the irritation. Avoid straining your eyes by looking at mobile phones, laptops or television. Wear protective eyeglasses while going outdoors.
Headache:
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Blurred vision:
Close your eyes and relax. Do not strain your eyes by looking at mobile phones, laptops, or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
WARNING & PRECAUTIONS
PREGNANCY
GATE DM EYE DROPS is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before using it.
BREASTFEEDING
GATE DM EYE DROPS is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before using it.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you experience blurred vision after using GATE DM EYE DROPS. Wait, until your vision becomes clear.
KIDNEY
GATE DM EYE DROPS can be used in patients with kidney problems. However, consult your doctor before using it.
LIVER
GATE DM EYE DROPS can be used in patients with liver problems. However, consult your doctor before using it.
ALLERGY
Do not use GATE DM EYE DROPS if you are allergic to Dexamethasone, Gatifloxacin or to any other quinolone antibiotics (such as ciprofloxacin).
OTHERS
GATE DM EYE DROPS is not recommended for use if you:
- have severe viral or fungal infections
- have an eye infection that produces sticky pus
- have ulcers in the eyes
- have hole or ulceration in the outer layer of the eye (cornea)
- have glaucoma
Before using GATE DM EYE DROPS inform your doctor if you:
- wear soft contact lenses
Use in pediatrics:
GATE DM EYE DROPS is not recommended for use in children and adolescents (aged below 18 years) unless prescribed by a physician. Therefore, consult your doctor before administration.
Use in geriatrics:
GATE DM EYE DROPS should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
INTERACTIONS
A. Drug - Drug interactions:
Before using GATE DM EYE DROPS, inform your doctor if you are taking any of the following medicines such as:
- medicines used to treat HIV infections such as ritonavir, cobicistat
- medicines used to treat glaucoma (such as timolol, pindolol, acetazolamide, brinzolamide)
Overdosage:
If you or anyone else accidentally used excessive amount of this medicine, rinse your eyes or ears with warm water. If still irritation persists, consult your doctor for advice. If you or anyone else accidentally swallowed this medicine, consult your doctor immediately.
SYNOPSIS
| Drug | : | Dexamethasone, Gatifloxacin |
| Pharmacological Category | : | Topical Corticosteroids, Fluroquinolones |
| Therapeutic Indication | : | Eye inflammation and infection |
| Dosage Forms | : | Eye drops |
MORE INFORMATION
- Keep GATE DM EYE DROPS out of reach of children
- Store GATE DM EYE DROPS at room temperature
- Do not use this medicine after 4 weeks of its opening, even if it contains some left-over medicine
FAQs ABOUT GATE DM EYE DROPS
Q: Can the use of GATE DM EYE DROPS cause blurred vision?
A: Yes. GATE DM EYE DROPS may cause blurred vision after application in some individuals, although not everybody gets them. If your vision becomes blur, close your eyes for some time and rest. Do not strain your eyes by looking at mobile phones, laptops or television. Avoid driving or operating any heavy tools or machines while your vision is blur. Consult your doctor if you experience blurred vision for a prolonged period.
Q: Can I use other eye medicines while using GATE DM EYE DROPS?
A: Avoid concomittant use of any eye medicines while using GATE DM EYE DROPS without consulting your doctor.
Q: How to use GATE DM EYE DROPS?
A: Use GATE DM EYE DROPS as advised by your physician. It is for ophthalmic use only. Instil few drops of this medicine into the affected eyes. Wash your hands before and after application.
Q: What is the use of GATE DM EYE DROPS?
A: GATE DM EYE DROPS is a prescription medicine used to treat and prevent inflammation and/or infection in the eyes.
Q: How long does it take for GATE DM EYE DROPS to work?
A: It may take around 10-15 minutes for GATE DM EYE DROPS to start showing its effects. However, this period may vary from person-to-person depending upon the dose that is administered.
Q: What are the side effects of GATE DM EYE DROPS?
A: The most common side effects of using GATE DM EYE DROPS are mild eye irritation or burning sensation, watery eyes, increased eye pressure, headache and taste changes. Consult your doctor if any of these side effect worsens.
Q: Can I use GATE DM EYE DROPS while wearing contact lenses?
A: If you wear soft contact lenses, remove the lens before applying GATE DM EYE DROPS and wait for at least 15 minutes before reinsertion.
Q: Can I use GATE DM EYE DROPS without consulting my doctor?
A: No. GATE DM EYE DROPS is a prescription medicine which should be used only if prescribed by the physician. It is because, GATE DM EYE DROPS contains a steroid medicine, which may cause harmful side effects when used without proper medical supervision. Therefore, consult your doctor for advice.
Q: Can I drive or ride a bike after using GATE DM EYE DROPS?
A: Do not drive if you experience blurred vision after using GATE DM EYE DROPS.
Q: What if I miss a dose of GATE DM EYE DROPS?
A: If you missed a dose of GATE DM EYE DROPS, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and use the regular dose. Do not use a double dose of GATE DM EYE DROPS to compensate the missed dose.
Q: How GATE DM EYE DROPS works?
A: GATE DM EYE DROPS blocks the release of certain chemicals in the body (such as prostaglandins) that causes eye pain, inflammation and swelling. It also kills the susceptible bacteria that causes eye infection. Collectively, this medicine reduces inflammation and infection of the eyes.
Q: Can I stop using GATE DM EYE DROPS once my symptoms subside?
A: No. Do not stop using this medicine without consulting your doctor as it may make your symptoms to re-appear. Therefore, use this medicine consistently for the duration instructed by your doctor to achieve better results.
REFERENCES
1. KD. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Hormones and Related Drugs. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 289 & 714.
2. Clyde Schultz. Gatifloxacin Ophthalmic Solution for Treatment of Bacterial Conjunctivitis: Safety, Efficacy and Patient Perspective. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed central. July 2012. [Accessed on 19th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619660/
3. Akorn. GATIFLOXACIN solution/ drops. Dailymed.com. [Revised in March 2022]. [Accessed on 19th January 2023] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=14312de6-67d4-4de2-854c-ef764090dd83
4. Rayner Pharmaceuticals Limited. Dropodex 0.1% w/v Eye Drops, solution dexamethasone phosphate (as dexamethasone sodium phosphate). Electronics Medicines Compendium. [Revised in July 2022]. [Accessed on 19th January 2023] https://www.medicines.org.uk/emc/files/pil.5132.pdf
5. Central Drugs Standard Control Organization. Gatifloxacin 3mg+ Dexamethasone 1mg Eye Drop. June 2004. [Accessed on 19th January 2023] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/dciApprovedfdc.pdf
6. Sunways India Pvt Ltd. Gatsun-DM. [Accessed on 19th January 2023] http://www.sunways.com/Products/Rentent-Ophthalmic-Products/Gatsun-DM.html
AUTHOR DETAILS
Written By Srilekha. R, B.Pharm
Last updated on 21 Jan 2023 | 05:07 PM(IST)
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