INTRODUCTION

GALVUS 50MG TABLET contains Vildagliptin which belongs to group of medicines called Oral Anti-diabetics. It is used in adults to treat type 2 diabetes which helps to control the blood sugar level when diet and exercise becomes insufficient to control the disease.

Type 2 diabetes mellitus is a medical condition in which the body does not make enough insulin or if the insulin that the body makes is insufficient leading to high blood sugar level in the body. It is generally characterized by symptoms such as excessive thirst, frequent urination, excessive hunger, unintended weight loss and tiredness.

Along treatment with GALVUS 50MG TABLET, your doctor might advise you to follow the diet and/or exercise which is beneficial. Avoid consumption of alcohol while taking GALVUS 50MG TABLET because it might lead to low blood glucose levels.

Before taking GALVUS 50MG TABLET, inform your doctor if you are on dialysis or have diabetic ketoacidosis (serious complication of diabetes), pancreatic disease, heart failure and liver or kidney disease.

GALVUS 50MG TABLET is not recommended for use in pregnant and breast-feeding women, which is also not recommended for use in children and adolescents (aged below 18 years). It should be used with caution in elderly patients (aged 65 years and above).

The side effects of taking GALVUS 50MG TABLET are dizziness, headache, joint pain and constipation. Consult your doctor if any of the side effects worsen.

USES OF GALVUS 50MG TABLET

• Treats type 2 diabetes

HOW GALVUS 50MG TABLET WORKS

GALVUS 50MG TABLET controls blood glucose level by acting on the pancreas to produce more insulin and less glucagon which leads to low production of blood sugar levels resulting in controlled blood glucose levels.

DIRECTIONS FOR USE

Take GALVUS 50MG TABLET as advised by your physician. Do not crush or chew GALVUS 50MG TABLET. Swallow the medicine with a glass of water. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF GALVUS 50MG TABLET

HOW TO MANAGE SIDE EFFECTS

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.

Dizziness:

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. If the symptom does not improve, consult your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Before taking GALVUS 50MG TABLET, inform your doctor if you are taking any of the following medicines:

• oral antidiabetics (medicine used to treat type 2 diabetes) Ex. sulphonylureas such as gliclazide, glipizide
• digoxin (used to treat heart failure)  
• warfarin (used to treat blood clot)
• amlodipine, ramipril, valsartan and angiotensin-converting enzyme (ACE) inhibitors (used to treat high blood pressure) such as captopril, enalapril, fosinopril
• simvastatin (used to reduce high cholesterol levels)
• thiazides or other diuretics (medicines used to treat high blood pressure) Ex. chlorothiazide, chlorthalidone, hydrochlorothiazide
• corticosteroids (used to treat inflammation) Ex. prednisolone
• certain medicines affecting nervous system such as antidepressants Ex. clomipramine, amitriptyline
• thyroid medicines (used to lower thyroid levels) Ex. levothyroxine

Over dosage:

If you or anyone else accidentally takes too much of GALVUS 50MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of GALVUS 50MG TABLET are muscle pain, mild and transient paraesthesia (burning and prickling sensation in hands and legs), fever, oedema (swelling in arms and legs) and laboratory abnormalities such as transient increase in lipase levels, increases in creatine phosphokinase (CPK), aspartate aminotransferase (AST), C-reactive protein (CRP) and myoglobin levels.

SYNOPSIS

MORE INFORMATION

• Keep GALVUS 50MG TABLET out of reach of children
• Store at room temperature

FAQs ABOUT GALVUS 50MG TABLET

Can GALVUS 50MG TABLET be used to treat diabetes mellitus?

Yes, GALVUS 50MG TABLET lowers blood glucose levels and it is specifically used to treat type II diabetes mellitus which is a medical condition where the body does not make enough insulin or if the produced insulin that the body makes is not optimal leading to increased blood glucose levels in the body. Consult your doctor before taking GALVUS 50MG TABLET.

Can I take GALVUS 50MG TABLET along with other hypoglycemic drugs like metformin or glimepiride?

Using GALVUS 50MG TABLET along with other hypoglycemic drugs like metformin, glimiperide may drastically lower your blood glucose levels. So, be cautious and inform your doctor before taking any other anti-diabetic medicines.

Does taking GALVUS 50MG TABLET cause weight gain?

No, GALVUS 50MG TABLET has no effect on weight gain. Moreover, these kinds of medicines delay gastric emptying and make you feel satiety (stomach fullness). These further decreases hunger. So, basically GALVUS 50MG TABLET has no effect or it does not influence weight gain.

How does GALVUS 50MG TABLET work?

GALVUS 50MG TABLET controls blood glucose level by acting on the pancreas to produce more insulin and less glucagon which leads to low production of blood sugar levels resulting in controlled blood glucose levels.

Does GALVUS 50MG TABLET cause dizziness?

Yes, GALVUS 50MG TABLET may cause dizziness in some individuals. To manage this effect, lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.

REFERENCES

1 KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 275

2. B Ahren , A Schweizer, S Dejager, E B Villhauer, B E Dunning, J E Foley. Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans. NIH National Library of Medicine. National Center for Biotechnology Information.PubMed.gov. [Revised in September 2011] [Accessed on 14th April 2022] https://pubmed.ncbi.nlm.nih.gov/21507182/

3. Kalyan Kumar Gangopadhyay and Parminder Singh. Consensus Statement on Dose Modifications of Antidiabetic Agents in Patients with Hepatic Impairment. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in March 2017] [Accessed on 14th April 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367241/

4. Novartis Europharm Limited. Electronic Medicines Compendium (EMC) [Revised in October 2020] [Accessed on 14th April 2022] https://www.medicines.org.uk/emc/files/pil.6225.pdf

5. Novartis Pharma GmbH. European Medicines Agency (EMA). [Revised in July 2012] [Accessed on 14th April 2022] https://ec.europa.eu/health/documents/community-register/2007/2007092629572/anx_29572_en.pdf

USEFUL DIAGNOSTIC TESTS

• HA1C Test
• Fasting Blood Sugar Test
• Random Blood Sugar Test
• Glucose Tolerance Test