INTRODUCTION

FUNZI NM LOTION is a combination of Clobetasol, Miconazole and Neomycin which belongs to the group of medicines called Corticosteroids, Antifungals and Antibiotics. It is used to treat resistant dermatoses (skin infections) with secondary bacterial or fungal infection.

FUNZI NM LOTION is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox) and perforated eardrum. Contact your doctor before applying.

FUNZI NM LOTION should be used with caution in patients with liver or kidney disease.  Contact your doctor before applying.

FUNZI NM LOTION is generally not recommended for use in pregnancy unless considered clearly necessary. FUNZI NM LOTION should be used with caution in breastfeeding women as it is not known whether it may pass through the breast milk. Contact your doctor before applying.

FUNZI NM LOTION is not recommended for use in children under 2 years of age and should be used with caution in children above 2 years of age. Contact your doctor before applying.

Dosage adjustment is not required for FUNZI NM LOTION in the geriatric population. However, greater sensitivity of some older individuals cannot be ruled out. Contact your doctor before applying.

The most common side effects of this medicine are skin rash, itching, redness, burning sensation and contact dermatitis. Contact your physician if any of the symptoms worsen.

USES OF FUNZI NM LOTION

• Treats resistant dermatoses (skin infections) with secondary bacterial or fungal infection

HOW FUNZI NM LOTION WORKS

FUNZI NM LOTION helps to treat infection, where Clobetasol have anti-inflammatory, antipruritic, and vasoconstrictive properties, which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy. Miconazole is an antifungal which stops the growth of fungi while Neomycin is an antibiotic which stops the growth of bacteria in the skin.

DIRECTIONS FOR USE

Apply FUNZI NM LOTION as directed by your physician. It is for external use only. Wash your hands with soap and water and apply a thin layer of the medicine to the affected area of the skin and rub it gently. Avoid contact with eyes, face, groin or in the skin folds.

SIDE EFFECTS OF FUNZI NM LOTION

HOW TO MANAGE SIDE EFFECTS

Itchy skin:

Avoid hot showers because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if itching worsens.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Tell your doctor if you are taking,

• ritonavir (medicines used for HIV infections)
• itraconazole (medicines used for fungal infections)
• aminoglycosides like amikacin, gentamicin (medicines used for bacterial infections)
• neuromuscular blocking agents like atracurium, pancuronium (medicines used in anaesthesia)
• warfarin (medicines used to treat or prevent blood clots)

Overdosage:

If you or anyone else accidentally use too much of FUNZI NM LOTION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are skin irritation, Hypothalamic-pituitary adrenal (HPA) axis suppression, cushingoid features (Ex. moon face, central obesity), ear damage and kidney damage may occur.

SYNOPSIS

MORE INFORMATION

• Keep out of reach of children
• Store FUNZI NM LOTION below 25°C

FAQs ABOUT FUNZI NM LOTION

Q: What are the possible side effects of applying FUNZI NM LOTION?

A: The most common side effects of this medicine are skin rash, urticaria, itching, redness, burning sensation and contact dermatitis. Contact your physician if any of the symptoms worsen.

Q: Can I use FUNZI NM LOTION in children?

A: FUNZI NM LOTION is not recommended for use in children under 2 years of age and should be used with caution in children above 2 years of age. Contact your doctor before applying.

Q: For what conditions FUNZI NM LOTION is used?

A: FUNZI NM LOTION is used to treat resistant dermatoses (skin infections) with secondary bacterial or fungal infection.

Q: Does FUNZI NM LOTION cause itching on the skin?

A: Yes, FUNZI NM LOTION may cause skin itching at the site of application as a temporary side effect. However, if the itching persists or worsens, consult your doctor for advice.

Q: Can I stop using FUNZI NM LOTION when my symptoms are relieved?

A: No, do not stop using FUNZI NM LOTION and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.

Q: Who should not use FUNZI NM LOTION?

A: FUNZI NM LOTION is not recommended for use in patients with rosacea, acne vulgaris, perioral dermatitis, perianal and genital pruritus, viral infections (ex. herpes simplex, chickenpox), perforated eardrum. Contact your doctor before applying.

REFERENCES

1. K.D. Tripathi. Drugs acting on the skin and mucous membrane, Antifungal Drugs & Aminoglycoside Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895, 792, 750.

2. Bethesda (MD). Clobetasol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/5311051

3. Bethesda (MD). Miconazole. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/4189

4. Bethesda (MD). Neomycin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Neomycin

5. Blue Cross labs. Clobetasol, Miconazole and Neomycin. [Revised on May 2020] [Accessed on 24th June 2022] https://www.bluecrosslabs.com/img/sections/SONADERM-NM-CREAM.pdf