Frenin 10mg Injection 1ml

Heart Failure Rx required

Best Price* ₹ 223.87 MRP ₹ 279.84
(Inclusive of all taxes) * Mkt: Samarth Life Sciences Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

FRENIN 10MG contains Phenylephrine which belongs to the group of medicines called Anti-hypotensives. It is used to relieve low blood pressure which may occur during an operation of after an injury. Low blood pressure is generally considered as blood pressure reading lower than 90 millimeters of mercury (mm Hg) for the top number (systolic) or 60 mm Hg for the bottom number (diastolic). Symptoms include blurred vision, dizziness, fainting, fatigue, trouble concentrating and nausea.     

FRENIN 10MG is not recommended for use in patients with high blood pressure, overactive thyroid (hyperthyroidism), prostate enlargement, shallow anterior chamber of the eye, history of acute increase of eye pressure (acute narrow angle glaucoma).

Before receiving FRENIN 10MG inform your doctor if you have heart diseases (such as ischemic heart disease, irregular heartbeat, chest pain), diabetes mellitus or diabetic autonomic neuropathy (complication of diabetes).

FRENIN 10MG should be used with caution in pregnant (including patients with history of pre-eclampsia) and breast-feeding women only if clearly advised by the doctor. It should be used with caution in children, adolescents and in elderly patients (aged 65 years and above).

The common side effects associated with the use of FRENIN 10MG are nausea, vomiting and headache. Inform your doctor if any of the side effect worsens.

USES OF FRENIN 10MG

Used in adults and children:

  • To relieve low blood pressure

HOW FRENIN 10MG WORKS

FRENIN 10MG acts on certain receptors present on the blood vessels (alpha-1 adrenergic receptors) and stimulates them. This stimulation causes narrowing of blood vessels called vasoconstriction. This action increases the blood pressure hence relieving the lowered down blood pressure.

DIRECTIONS FOR USE

FRENIN 10MG will be given to you only by a doctor or a nurse into a muscle (intramuscularly) or just under the skin (subcutaneously). It can also be injected directly into a vein as an intravenous infusion. Your doctor will decide the right dose and duration for you depending upon your age, body weight and severity of the condition.

SIDE EFFECTS OF FRENIN 10MG

COMMON

  • nausea
  • vomiting
  • headache

RARE

Consult your doctor if you experience this side effect after receiving FRENIN 10MG:

  • serious allergic reaction (signs include itching/rash, swelling of the face, lips or throat or difficulty in breathing/wheeziness)

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Stick to simple meals. Avoid eating oily, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve. 

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Inform your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY

FRENIN 10MG should be used with caution in pregnant women only if considered clearly necessary and in patients with history of pre-eclampsia (high blood pressure that can occur during pregnancy). Consult your doctor before receiving it.

BREASTFEEDING

FRENIN 10MG should be used with caution in breast-feeding women. Consult your doctor before receiving it.

DRIVING AND USING MACHINES

FRENIN 10MG does not affect your ability to drive or use machines. Consult your doctor if you feel unwell.

KIDNEY

FRENIN 10MG should be used with caution in patients with end stage renal disease (ESRD). Your doctor may initiate the treatment with the lowest effective dose and may adjust the dose depending on target blood pressure. Consult your doctor before receiving it.

LIVER

FRENIN 10MG should be used with caution in patients with moderate to severely impaired liver function. Your doctor may adjust the dose based upon functioning of the liver. Consult your doctor before receiving it.

ALLERGY

Do not receive FRENIN 10MG if you are allergic to Phenylephrine or any other ingredients of this medicine.

HEART DISEASE

FRENIN 10MG is not recommended for use in patients with high blood pressure. FRENIN 10MG should be used with caution in patients with heart conditions such as ischemic heart disease, irregular heartbeat, angina pectoris (chest pain), occlusive vascular disease (circulatory condition in which narrowed blood vessels reduce blood flow to the limbs) or aneurysms (abnormal bulge or ballooning in the wall of a blood vessel). Consult your doctor before receiving it.

OTHERS

FRENIN 10MG is not recommended for use if you:

  • have prostatic enlargement
  • have shallow anterior chamber of the eye
  • have a history of acute increase of eye pressure (acute narrow angle glaucoma)
  • have hyperthyroidism

Before receiving FRENIN 10MG, inform your doctor if you:

  • have diabetes mellitus
  • have diabetic autonomic neuropathy (a complication of diabetes mellitus)

Use in pediatrics:

FRENIN 10MG should be used with caution in children and adolescents. Your child’s doctor may adjust the dose depending upon child’s body weight. Consult your child’s doctor for advice before administration of FRENIN 10MG.

Use in geriatrics:

FRENIN 10MG should be used with caution in elderly patients (aged 65 years and above). Your doctor may usually initiate the treatment with the lowest effective dose depending upon kidney, liver or heart function or concomitant disease or other drug therapy. Consult with your doctor before receiving it.

INTERACTIONS

Before receiving FRENIN 10MG, inform your doctor if you have received or taking any of the following medicines: 

  • medicines called monoamine oxidase inhibitors (MAOIs) such as isocarboxazid, phenelzine (used to treat depression)
  • medicines for heart problems or high blood pressure (Ex. lisinopril, amiloride)
  • general anesthetics (Ex. propofol, isoflurane)
  • medicines used to treat attention-deficit hyperactivity disorder (ADHD) (Ex. atomoxetine)
  • antimuscarinics (Ex. atropine) (used to treat symptoms of low heart rate)
  • lithium (used to treat depression or aggression)

Overdosage:

FRENIN 10MG will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms like headache, nausea, high blood pressure, fast or irregular heartbeat, confusion, hallucinations and fits.

SYNOPSIS

Drug :   Phenylephrine
Pharmacological Category :   Alpha-1 adrenergic agonist
Therapeutic Indication :   Relieves low blood pressure
Dosage Forms :   Injection, Eye drops, Syrup

MORE INFORMATION

STORAGE

?   Store either in a refrigerator or at room temperature (2°C- 25°C)

FAQs ABOUT FRENIN 10MG

What is FRENIN 10MG used for?

FRENIN 10MG is used to relieve low blood pressure which may occur during an operation of after an injury. Low blood pressure is generally considered as blood pressure reading lower than 90 millimeters of mercury (mm Hg) for the top number (systolic) or 60 mm Hg for the bottom number (diastolic).

Can FRENIN 10MG be used during pregnancy?

FRENIN 10MG should be used with caution in pregnant women only if clearly advised by your doctor and in patients with history of pre-eclampsia (high blood pressure that can occur during pregnancy). Consult your doctor before receiving FRENIN 10MG.

How does FRENIN 10MG work?

FRENIN 10MG acts on certain receptors present on the blood vessels (alpha-1 adrenergic receptors) and stimulates them. This stimulation causes narrowing of blood vessels called vasoconstriction. This action increases the blood pressure hence relieving the lowered down blood pressure.

When is FRENIN 10MG contraindicated?

FRENIN 10MG is not recommended for use in patients with high blood pressure, overactive thyroid (hyperthyroidism), prostate enlargement, shallow anterior chamber of the eye and with history of acute increase of eye pressure (acute narrow angle glaucoma). Consult your doctor before receiving FRENIN 10MG.

Can FRENIN 10MG be used in patients with liver problems?

FRENIN 10MG should be used with caution in patients with moderate to severely impaired liver function. Your doctor may adjust the dose based upon functioning of the liver. Consult your doctor before receiving FRENIN 10MG.

REFERENCES

1. KD Tripathi. Adrenergic Transmission and Adrenergic Drugs. Essentials of medical pharmacology. Eighth Edition. 2019. Page – 148

2. Young Hoon Park, Taeha Ryu, Seong Wook Hong, Kyung Hwa Kwak, and Si Oh Kim. The effect of the intravenous phenylephrine on the level of spinal anesthesia. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. November 2011. [Accessed on 22nd August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229014/

3. Evan Richards, Michael J. Lopez, Christopher V. Maani. Phenylephrine. NIH National Library of Medicine, National center for biotechnology information. July 2022. [Accessed on 22nd August 2022] https://www.ncbi.nlm.nih.gov/books/NBK534801/

4. Paul J Desjardins and Roger G Berlin. Efficacy of phenylephrine. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. July 2007. [Accessed on 22nd August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048561/

5. Amdipharm UK Limited. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 22nd August 2022] https://www.medicines.org.uk/emc/files/pil.5577.pdf

6. Eclat Pharmaceuticals. U.S. Food & Drug Administration. [Revised in June 2014] [Accessed on 22nd August 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/204300lbl.pdf

USEFUL DIAGNOSTIC TESTS

  • Electrocardiogram (ECG)

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    15 g
    Ingredient
    PHENYLEPHRINE 10MG
    Hsn Code
    30049099
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Frenin 10mg Injection 1ml

Frenin 10mg Injection 1ml Mkt: Samarth Life Sciences Pvt Ltd

M.R.P.: Rs.279.84
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