What is Methotrexate used for?
Methotrexate is used in the treatment of certain types of cancers, such as breast, skin, head or neck. It is also used to treat rheumatoid arthritis and severe psoriasis.
Methotrexate may also be prescribed for other conditions as determined by the doctor.
How does Methotrexate work?
Methotrexate belongs to a class of drugs called anti-metabolites. It works by inhibiting the growth of cancer cells by inhibiting an enzyme that interferes with the cell’s ability to repair and replicate.
The action of Methotrexate to treat rheumatoid arthritis is still unknown. However, it is thought to work by suppressing the immune system.
How to use Methotrexate?
The dosage and the drug form depends on the age, weight and medical condition of an individual.
- Swallow the tablet whole. Do not crush or chew the tablet. Take Methotrexate with or without food.
- Methotrexate injection should be administered only under the supervision of a healthcare provider. Do not self-administer.
If you miss a dose of Methotrexate, consult your doctor immediately.
What are the drugs that interact with Methotrexate?
The drugs that interact with Methotrexate are:
This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.
What are the side effects of Methotrexate?
The following are the most common side effects of Methotrexate:
- Stomach pain
- Hair loss
The following are the severe side effects, and you may require immediate medical attention:
- Mouth sores
- Kidney problems
- Neck stiffness
This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.
What special precautions should be followed while using Methotrexate?
- Seek doctor’s advice before taking any other drug or herbal products while on Methotrexate
- Avoid consumption of alcohol while on Methocarbamol
- Do not exceed the dose more than what is prescribed.
- Do not stop using the medication abruptly unless instructed by the doctor. Stopping the medication suddenly may cause the illness to return.
- Do not drive or operate heavy machinery if Methotrexate causes dizziness or blurred vision.
- Keep the medicine away from children.
What should you tell your doctor before using Methotrexate?
- Tell your doctor if you are allergic to Methotrexate.
- Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
- Inform your doctor if you have any pre-existing depression, liver or heart diseases.
Frequently asked questions about Methotrexate
- Is it common to cough up blood or vomit that looks like coffee grounds while using Methotrexate?
- What are the overdose symptoms of Methotrexate?
- Is the use of Methotrexate safe in pregnant women?
- Do I need to be monitored for any laboratory parameters while using Methotrexate?
No, it is not a common symptom; however, it is an overdose symptom of Methotrexate. Please consult your doctor immediately in case you experience this symptom.
The overdose symptoms of Methotrexate include unusual weakness, mouth sores, nausea, vomiting, bloody stools, easy bruising etc.
The use of Methotrexate may cause birth defects and miscarriages. Therefore, it is not advisable to use Methotrexate during pregnancy. However, please consult your doctor.
Yes, regular monitoring of complete blood count (CBC), kidney function test (KFT) and liver function test (LFT) before and during the use of Methotrexate is advised.
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.