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FOLIOS 12 TABLET is a combination of L-Methylfolate, Methylcobalamin, and Pyridoxal Phosphate which belongs to the group of medicines called Vitamins. It is used to treat endothelial dysfunction (large blood vessels on the heart's surface narrow instead of widening) or hyperhomocysteinemia (high levels of an amino acid called homocysteine) in patients who present with lower extremity ulceration.
FOLIOS 12 TABLET can also be used to promote optimum health and protect nerve cells in diabetic peripheral neuropathy. Diabetic neuropathy is nerve damage that occurs over time because of high sugar and fat levels in the blood due to diabetes. Symptoms depend on the type of neuropathy, such as pain and numbness in your feet or problems with organ functions like those of your heart and bladder.
Avoid smoking and drinking during treatment with FOLIOS 12 TABLET. FOLIOS 12 TABLET has not been proven safe or effective in children, so consult your doctor before using it. Before taking FOLIOS 12 TABLET, inform your doctor if you have any other conditions or if you are taking any medicines. In pregnant and breastfeeding women, FOLIOS 12 TABLET should be used with caution. Consult your doctor if you experience any side effects or if your symptoms worsen.
FOLIOS 12 TABLET helps protect nerve cells where L-methyl folate is a form of folate that increases levels of nitric oxide vasodilator, thus increasing blood flow to the peripheral nerves, methylcobalamin participates in many processes like the production of red and white blood cells, and regeneration of RNA and DNA, synthesis of proteins, nerve cell and sheath maintenance and maintenance of bone marrow, and pyridoxal-5-phosphate takes part in a wide range of biochemical reactions like the metabolism of amino acids and glycogen, the synthesis of nucleic acids, haemoglobin, and certain neurotransmitters.
Take FOLIOS 12 TABLET as advised by your physician. Swallow with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of FOLIOS 12 TABLET for you according to your age, body weight and disease condition.
Eat when you are hungry. Eat smaller meals more often than usual. Snack only when you're hungry. Eat a nutritious snack rich in calories and protein, such as dried fruit and nuts. If your appetite does not improve, contact your doctor.
Drink lots of fluids, like water or fruit juice to keep yourself hydrated. Ask your doctor before taking any medicine for diarrhoea. If diarrhoea does not improve, contact your doctor.
Take FOLIOS 12 TABLET with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If nausea does not improve, contact your doctor.
Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens.
Drink an ample amount of water. Get adequate rest. Try to be relaxed and stress-free. Ask your doctor before taking any medicine for headaches. If the headache does not improve, contact your doctor.
FOLIOS 12 TABLET should be used with caution in pregnant women. Consult your doctor before taking it.
There is no information available about the distribution of FOLIOS 12 TABLET in breast milk. Consult your doctor before taking it.
Do not drive or use any machines if you feel disturbed mental alertness and motor coordination after taking FOLIOS 12 TABLET.
Avoid consumption of alcohol while taking FOLIOS 12 TABLET.
There is no information available about the use of FOLIOS 12 TABLET in patients with kidney failure. Consult your doctor before taking it.
There is no information available about the use of FOLIOS 12 TABLET in patients with liver impairment. Consult your doctor before taking it.
Do not take FOLIOS 12 TABLET if you are allergic to L-Methylfolate, Methylcobalamin, Pyridoxal Phosphate, or any of the other ingredients of this medicine.
The safety and effectiveness of FOLIOS 12 TABLET in children have not been established. Consult your doctor before taking it.
The safety and effectiveness of FOLIOS 12 TABLET in elderly patients have not been established. Consult your doctor before taking it.
A. Drug-Drug interactions:
Before taking FOLIOS 12 TABLET, inform your doctor if you are taking any of the following medicines:
If you or anyone else accidentally took too much of FOLIOS 12 TABLET, contact your doctor immediately.
|Drug||:||L-Methylfolate, Methylcobalamin, and Pyridoxal Phosphate|
|Therapeutic Indication||:||Endothelial dysfunction, Hyperhomocysteinemia, Optimize health, Diabetic peripheral neuropathy|
|Dosage Forms||:||Tablet, Capsule|
Q: Can I take other medicines with FOLIOS 12 TABLET?
A: Before taking FOLIOS 12 TABLET, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription, or any herbal medicine, as these might interact with each other and cause serious side effects. The influence that Silymarin (one of the ingredients in this medicine) has on liver function should be considered when other medicines are given concomitantly.
Q: Can I drive a car after taking FOLIOS 12 TABLET?
A: Activities like driving a car or operating machinery should be done cautiously after taking FOLIOS 12 TABLET as they require complete mental alertness and motor coordination. Your doctor will tell you about these activities after assessing your response to the medicine.
Q: Does FOLIOS 12 TABLET cause vomiting?
A: Vomiting is a possible side effect of FOLIOS 12 TABLET. FOLIOS 12 TABLET. In such a case, get adequate rest and drink lots of fluids, especially water. Have small sips if you feel sick. Eat when you feel like it; you do not need to eat or avoid any specific foods. Do not take any medicine for vomiting without asking your doctor. Tell your doctor if you have continuous vomiting.
Q: Can FOLIOS 12 TABLET be given to children?
A: The safety and efficacy of FOLIOS 12 TABLET in children have yet to be determined. Your doctor will determine the correct dose or select a suitable alternative treatment for your child.
Q: What if I forget to take a dose of FOLIOS 12 TABLET?
A: If you forget to take a dose of FOLIOS 12 TABLET, take it as soon as you remember. However, omit the missed dose if it is almost time for the next one. Do not take the medicine twice to make up for the forgotten dose.
Q: Can FOLIOS 12 TABLET be stopped?
A: Continue taking FOLIOS 12 TABLET until your doctor tells you to stop, unless you experience any unwanted effects, a worsening of your condition, or any new symptoms. Contact your doctor in such a case.
Q: Can FOLIOS 12 TABLET be crushed?
1. KD Tripathi. Drugs Affecting Blood and Blood Formation. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 608.
2. Trippe BS, Barrentine LW, Curole MV, Tipa E. Nutritional management of patients with diabetic peripheral neuropathy with L-methyl folate-methylcobalamin-pyridoxal-5-phosphate: results of a real-world patient experience trial. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2016. [Accessed on 28th July May 2022] https://pubmed.ncbi.nlm.nih.gov/26439233/
3. Pure and Cure Healthcare Pvt. Ltd. L-Methylfolate + Methylcobalamin + Pyridoxal phosphate. [Revised in January 2022] [Accessed on 28th July 2022] https://www.centaurpharma.com/downloads/2022/neurology/NURING%20ACTIVE.pdf
4. DM Pharma. L-Methylfolate + Methylcobalamin + Pyridoxal phosphate + Vitamin D3. [Accessed on 28th July 2022] http://dmpharma.co.in/Methylcobalamin,%20L-Methylfolate,%20Pyridoxal-5-phosphate,%20Vitamin%20D3%20Tablet.html
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