INTRODUCTION

FLUPIRZA 100MG CAPSULE contains Flupirtine which belongs to a group of medicines called Nonopioid, Non-NSAID analgesics. It is used in the treatment of acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles).  

FLUPIRZA 100MG CAPSULE is not recommended for use in patients with liver problems. Before taking FLUPIRZA 100MG CAPSULE, inform your doctor if you have kidney disease, myasthenia gravis, had or have a history of tinnitus (ringing in the ears) or if you are allergic to flupirtine.  

FLUPIRZA 100MG CAPSULE is not recommended for use in pregnant and breast-feeding women unless clearly advised by the doctor. FLUPIRZA 100MG CAPSULE is not recommended for use in children and adolescents (below 18 years of age) unless deemed necessary and it should be used with caution in elderly patients, especially in patients with kidney problems.

The most common side effects of taking FLUPIRZA 100MG CAPSULE are fatigue, dizziness, heartburn, nausea, vomiting, dry mouth, constipation and diarrhoea. Consult your doctor if any of the side effects worsen.

USES OF FLUPIRZA 100MG CAPSULE

• Treats acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles)     

HOW FLUPIRZA 100MG CAPSULE WORKS

FLUPIRZA 100MG CAPSULE works by preventing the transmission of pain signals by blocking neuronal excitability and reducing the calcium influx into the cells that is responsible for the sense of pain and inflammation produced at the site of injury and damage and hence it is useful in providing relief from pain, including that is associated with muscle tension.

DIRECTIONS FOR USE

Take FLUPIRZA 100MG CAPSULE as advised by your physician. Swallow the medicine with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age and body weight.

SIDE EFFECTS OF FLUPIRZA 100MG CAPSULE

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to treat diarrhea and consult your doctor if the symptom gets worse.

Nausea or vomiting:

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. If the symptom does not improve, consult your doctor.

Dry mouth:

Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug - Drug interactions:

Before taking FLUPIRZA 100MG CAPSULE, inform your doctor, if you are taking any of the following medicines:

• medicines that prevent or treats blood clot (Ex. warfarin, dicumarol)
• paracetamol (used to reduce fever and inflammation)
• carbamazepine (used to treat epilepsy)
• diazepam (used to treat anxiety and alcohol withdrawal)

Overdosage:

If you or anyone else accidentally takes too much of FLUPIRZA 100MG CAPSULE, consult your doctor immediately or visit the nearby hospital.  

SYNOPSIS

MORE INFORMATION

• Keep FLUPIRZA 100MG CAPSULE out of reach of children
• Store at room temperature

FAQs ABOUT FLUPIRZA 100MG CAPSULE

What is FLUPIRZA 100MG CAPSULE used for?

FLUPIRZA 100MG CAPSULE is used in the treatment of acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles).   

What common side effects are seen with FLUPIRZA 100MG CAPSULE?

The most common side effects of taking [GBNKEYWORD are fatigue, dizziness, heartburn, nausea, vomiting, dry mouth, diarrhoea, constipation, diarrhea, stomach upset, bloating and pain, loss of appetite, tremor, headache, increased sweating, sleep problems and restlessness. Consult your doctor if any of the side effects worsen.

How does FLUPIRZA 100MG CAPSULE work?

FLUPIRZA 100MG CAPSULE works by preventing the transmission of pain signals by blocking neuronal excitability and reducing the calcium influx into the cells that is responsible for the sense of pain and inflammation produced at the site of injury and damage, and hence it is useful in providing relief from pain, including that is associated with muscle tension.

Can FLUPIRZA 100MG CAPSULE be used in pregnant women?  

FLUPIRZA 100MG CAPSULE is not recommended for use in pregnant women unless clearly advised by the doctor. Consult your doctor before taking FLUPIRZA 100MG CAPSULE if you are pregnant or planning to get pregnant.

Is FLUPIRZA 100MG CAPSULE safe to use in patients with kidney diseases?

FLUPIRZA 100MG CAPSULE should be used with caution in patients with kidney diseases. Your doctor may regularly monitor your kidney function before and during treatment with FLUPIRZA 100MG CAPSULE to prevent the risk of kidney damage. Consult your doctor for advice before taking FLUPIRZA 100MG CAPSULE.

REFERENCES

1. KD. Tripathi. Opioid Analgesics and Antagonists. Essentials of medical pharmacology. Seventh edition. 2013. Page – 469- 486.

2. Harish S, Bhuvana K, Bengalorkar GM, Kumar T. Flupirtine: Clinical pharmacology. Journal of Anaesthesiology and Clinical Pharmacology. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. June 2012. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339720/

3. Singal R, Gupta P, Jain N, Gupta S. Role of flupirtine in the treatment of pain - chemistry and its effects. Journal of Clinical medicine. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. June 2012. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557425/

4. Kim Lawson. Pharmacology and clinical applications of flupirtine: Current and future options. World Journal of Pharmacology. January 2019. [Accessed on 21st June 2022] https://www.wjgnet.com/2220-3192/full/v8/i1/1.htm

USEFUL DIAGNOSTIC TESTS

• Liver function test
• Kidney function test