FLUBIFLUR PLUS OPHTHALMIC SOLUTION is a combination of Flurbiprofen and Hydroxypropyl methylcellulose (HPMC) which belongs to the group of medicines called NSAIDs and Eye lubricants. It is used to prevent narrowing of pupil (black hole on the centre of the eye) during eye surgery (cataract removal) and post-surgical inflammation of eyes.
FLUBIFLUR PLUS OPHTHALMIC SOLUTION is also used to treat Pseudophakic Cystoid macular edema (swelling of part of eye called macula with fluid due to complication of cataract surgery), eye pain associated with surgery and Post operative dry eye.
FLUBIFLUR PLUS OPHTHALMIC SOLUTION is not recommended for use if you have viral eye infection or have a tendency to bleed. Contact your doctor before using it.
FLUBIFLUR PLUS OPHTHALMIC SOLUTION is not recommended for use in third trimester of pregnancy and inform your doctor if you are breastfeeding before using this medicine.
The most common side effects of using FLUBIFLUR PLUS OPHTHALMIC SOLUTION are burning or stinging sensations, eye irritation or discomfort. Contact your physician if any of the symptoms worsen.
Treats:
Flurbiprofen present in the FLUBIFLUR PLUS OPHTHALMIC SOLUTION works by stopping the pupil (inner part of the eye) from narrowing. Thus, it makes it easy for a doctor to check the eye during surgery or changing the lens and also blocks the release of certain chemicals called prostaglandins that cause pain, inflammation and irritation in the eye. While Hydroxypropyl methylcellulose is an Eye lubricant used to reduce dryness and soreness irritation. It also helps to prevent damage to the eye in certain eye diseases.
Instil FLUBIFLUR PLUS OPHTHALMIC SOLUTION into the eye as advised by your physician. Shake well before use. It is for ophthalmic use only. FLUBIFLUR PLUS OPHTHALMIC SOLUTION is normally instilled by your doctor. The doctor will instil the drops in your eye.
But if you are putting the eye drops in yourself, then wash your hands, tilt your head back and look at the ceiling. Gently pull the lower eyelid down until there is a small pocket. Turn the bottle upside down and squeeze it to release drop into the affected eye and close your eye for 30 seconds. Do not touch tip of container to any surface to avoid contamination.
Stop using FLUBIFLUR PLUS OPHTHALMIC SOLUTION and contact your physician immediately if you experience any of the following side effects:
FLUBIFLUR PLUS OPHTHALMIC SOLUTION is not recommended for use in third trimester of pregnancy. Contact your doctor for advice before using it.
Before using FLUBIFLUR PLUS OPHTHALMIC SOLUTION inform your physician if you are breastfeeding women.
Do not drive or operate any machines if you have blurred vision after using FLUBIFLUR PLUS OPHTHALMIC SOLUTION.
Do not use FLUBIFLUR PLUS OPHTHALMIC SOLUTION if you are allergic to Flurbiprofen and Hydroxypropyl methylcellulose (HPMC) or other similar medicines, aspirin or to other ingredients of this medicine.
FLUBIFLUR PLUS OPHTHALMIC SOLUTION is not recommended for use, if you:
Before using FLUBIFLUR PLUS OPHTHALMIC SOLUTION, inform your physician if you:
A. Drug-Drug interactions:
Tell your doctor if you are applying or have recently taken any other medicines, including medicines obtained without a prescription, vitamin supplement or herbal products.
Overdosage:
If you or anyone else accidentally take too much of FLUBIFLUR PLUS OPHTHALMIC SOLUTION, consult your doctor immediately or visit the nearby hospital. If you have placed too many drops in your eye(s), wash your eye(s) with clean water. Apply your next dose at the normal time.
Drug | : | Flurbiprofen and Hydroxypropyl methylcellulose |
Pharmacological Category | : | NSAIDs and Eye Lubricants |
Therapeutic Indication | : | Prevent narrowing of pupil during eye surgery (cataract removal) and Post-surgical inflammation of eyes |
Dosage Forms | : | Eye drops, Ophthalmic solution |
Q: What precautions have to be taken while using FLUBIFLUR PLUS OPHTHALMIC SOLUTION?
A: FLUBIFLUR PLUS OPHTHALMIC SOLUTION is used 2 hours before the surgery. It should be used only after consulting with the doctor, as it contains the inactive ingredients which can cause allergic reactions or other problems. Consult your physician if you have any history of eye surgery.
Q: Can I use another eye drops along with FLUBIFLUR PLUS OPHTHALMIC SOLUTION?
A: Other eye medicine should not usually be used with FLUBIFLUR PLUS OPHTHALMIC SOLUTION. However, if your doctor recommends using FLUBIFLUR PLUS OPHTHALMIC SOLUTION with another eye medicine, leave at least 5 minutes between putting in FLUBIFLUR PLUS OPHTHALMIC SOLUTION and the other medicine.
Q: What if I forget to use FLUBIFLUR PLUS OPHTHALMIC SOLUTION?
A: If you forget to use FLUBIFLUR PLUS OPHTHALMIC SOLUTION, you should take the missed dose as soon as you remember, unless it is nearly time for the next dose. Do not take a double dose to make up for a missed dose and if a drop misses your eye, try again.
Q: Can I wear contact lens while using FLUBIFLUR PLUS OPHTHALMIC SOLUTION?
A: FLUBIFLUR PLUS OPHTHALMIC SOLUTION contains benzalkonium chloride may be absorbed by soft contact lenses and may change the colour of the contact lenses. You should remove contact lenses before using this medicine and put them back 15 minutes afterwards. Benzalkonium chloride may also cause eye irritation, especially if you have dry eyes or disorders of the cornea (the clear layer at the front of the eye). If you feel abnormal eye sensation, stinging or pain in the eye after using this medicine, contact your doctor.
1. K.D. Tripathi. NSAIDs and Antipyretic-Analgesics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 201.
2. Ahuja M, Dhake AS, Sharma SK, Majumdar DK. Topical ocular delivery of NSAIDs. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. June 2008. [Accessed on 21st July 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751374/
3. Sarkar S, Mondal KK, Roy SS, Gayen S, Ghosh A, De RR. Comparison of preoperative nepafenac (0.1%) and flurbiprofen (0.03%) eye drops in maintaining mydriasis during small incision cataract surgery in patients with senile cataract: A randomized, double-blind study. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. Sep-Oct 2015. [Accessed on 21st July 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621668/
4. FDC International Ltd. Electronic Medicines Compendium (EMC). [Revised in June 2020] [Accessed on 21st July 2022]. https://www.medicines.org.uk/emc/files/pil.457.pdf
5. Allergan Pharmaceuticals Ireland. Electronic Medicines Compendium (EMC). [Revised in February 2022] [Accessed on 21st July 2022]. https://www.medicines.org.uk/emc/files/pil.1343.pdf
6. Flurbi- SP eye drops (Flurbiprofen and Hydroxypropyl methylcellulose). Spectra Vision Care. [Accessed on 21st July 2022]. https://www.spectravisioncare.in/product/flurbiprofen-0-03-hpmc25
7. FLURVIS Eye drops (Flurbiprofen and Hydroxypropyl methylcellulose). Salvador Visontech. [Accessed on 21st July 2022]. http://www.salvadorvisiontech.com/products
8. TAKFLUR EYE DROPS (Flurbiprofen and Hydroxypropyl methylcellulose). Pharmtak Ophthalmics Pvt Ltd. [Accessed on 21st July 2022]. https://www.pharmtakindia.com/product/takflur-eye-drops/
9. OPTIFLEV EYE DROPS (Flurbiprofen and Hydroxypropyl methylcellulose). Leeford Healthcare Ltd. [Accessed on 21st July 2022]. https://www.leeford.in/product/135/optiflev-eye-drops
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