FLEBIXEN PLUS 0.5 Tablet 10's

Depression Rx required
NOT FOR SALE

Best Price* ₹ 58.96 MRP ₹ 73.70
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Dycine Pharma * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

FLEBIXEN PLUS 0.5 is a combination of Flupenthixol and Melitracen which belongs to the group of medicines called Antipsychotics and Tricyclic antidepressants respectively. It is used in the treatment of neurasthenia (condition that causes physical and mental exhaustion usually with accompanying symptoms (such as headache and irritability)), psychogenic depression, depressive neuroses, masked depression, menopausal depression, dysphoria (profound state of unease or dissatisfaction) and depression in alcoholics and drug-addicts, psychosomatic affections that is accompanied by anxiety and apathy.

Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest that affects a person how he feels, thinks and behaves leading to a variety of emotional and physical problems associated with symptoms such as changes in sleep, appetite and daily behaviour. Anxiety is a feeling of fear, dread, and uneasiness which is generally characterized by symptoms such as fast heart rate, rapid breathing, sweating and tiredness.

Avoid taking FLEBIXEN PLUS 0.5 if you have mania or heart diseases such as circulatory collapse, depressed level of consciousness, blood disorders, hereditary problems of galactose (sugar) intolerance. Before taking FLEBIXEN PLUS 0.5, inform your doctor if you have convulsions, organic brain syndrome, history of suicide related events, diabetes, planned surgeries, reduced liver or kidney function.

FLEBIXEN PLUS 0.5 is not recommended for use in pregnant women unless clearly advised by the doctor and it should be used with caution in breastfeeding women as it can pass through breast milk. FLEBIXEN PLUS 0.5 is not recommended for use in children and adolescents (below 18 years of age) and it should be used with caution in elderly patients (aged above 75 years).

The most common side effects of taking FLEBIXEN PLUS 0.5 are sleeplessness, restlessness, agitation, dizziness, tremor (involuntary movement of muscles), dry mouth and constipation. Consult your doctor if any of the side effect gets worsen.

USES OF FLEBIXEN PLUS 0.5

Used in the treatment of:

  • psychogenic depression
  • neurasthenia
  • depressive neurosis
  • masked depression
  • psychosomatic affections accompanied by anxiety and apathy
  • menopausal depression
  • dysphoria and depression in alcoholics and drug-addicts

HOW FLEBIXEN PLUS 0.5 WORKS

FLEBIXEN PLUS 0.5 is a combination flupenthixol and melitracen, where flupenthixol works by preventing the effects of dopamine, a brain chemical messenger that influences thoughts and mood. Melitracen increases the level of chemical messengers in the brain which results in regulating the mood and treats depression.

DIRECTIONS FOR USE

Take FLEBIXEN PLUS 0.5 as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF FLEBIXEN PLUS 0.5

COMMON

  • sleeplessness
  • restlessness
  • agitation
  • dizziness
  • tremor (involuntary movement of muscles)
  • dry mouth
  • constipation
  • weakness
  • accommodation disorder (eye disorder)

RARE

  • glaucoma

Stop taking FLEBIXEN PLUS 0.5 and consult your doctor immediately if you experience any of the following side effects:

  • suicidal behaviour or thoughts
  • unusual changes in behaviour

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest and sleep. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol, and drugs. Consult your doctor if the symptom gets worse.

Dry mouth:

Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.

Constipation:

Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult your doctor for receiving alternate treatment for constipation.

WARNING & PRECAUTIONS

PREGNANCY

FLEBIXEN PLUS 0.5 is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it.

BREASTFEEDING

FLEBIXEN PLUS 0.5 should be used with caution in breastfeeding women as it can pass through breast milk. The breast-fed infant should be kept under observation especially during first 4 weeks after being born. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel altered general attention and concentration after taking FLEBIXEN PLUS 0.5.

ALCOHOL

Avoid consumption of alcohol while taking FLEBIXEN PLUS 0.5 as it may enhance the effects of alcohol.

KIDNEY

FLEBIXEN PLUS 0.5 should be used with caution in patients having reduced kidney function. Consult your doctor before taking it.

LIVER

FLEBIXEN PLUS 0.5 should be used with caution in patients having advanced hepatic impairment and reduced liver function. Consult your doctor before taking it.

ALLERGY

Do not take FLEBIXEN PLUS 0.5 if you are allergic to Flupenthixol or Melitracen.

HEART DISEASE

FLEBIXEN PLUS 0.5 is not recommended for use in patients having heart diseases such as recent myocardial infarction (heart attack), any degree of heart block, disorders of cardiac rhythm and coronary artery insufficiency. Consult your doctor before taking it.

OTHERS

FLEBIXEN PLUS 0.5 is not recommended for use if you have:

  • circulatory collapse
  • depressed level of consciousness due to any cause
  • blood disorders
  • phaeochromocytoma (neuroendocrine tumor)
  • hereditary problems related to galactose intolerance, total lactase deficiency or glucose-galactose malabsorption
  • excitability, overactivity, or maniac
  • dementia-related behavioural disturbance

Before taking FLEBIXEN PLUS 0.5, inform your doctor if you have:

  • convulsions (fits)
  • organic brain syndrome
  • urinary retention
  • signs of hyperthyroidism such as unintentional weight loss, rapid and irregular heartbeat
  • history of suicide related events
  • diabetes (high blood sugar)
  • schedule for any planned surgeries

Use in paediatrics:

FLEBIXEN PLUS 0.5 is not recommended for use in children and adolescents below 18 years of age. Consult child’s doctor for advice.

Use in geriatrics:

FLEBIXEN PLUS 0.5 should be used with caution in elderly patients (aged above 75 years). Consult your doctor before taking FLEBIXEN PLUS 0.5.

INTERACTIONS

A. Drug – Drug Interactions:

Before taking FLEBIXEN PLUS 0.5, inform your doctor if you have received or taking any of the following medicines:

  • medicines used to treat depression such as monoamine oxidase inhibitor (MAOIs) (Ex. moclobemide, selegiline), selective serotonin reuptake inhibitors (SSRIs) (Ex. citalopram)
  • medicines used to treat nasal congestion (Ex. phenylephrine, phenylpropanolamine)
  • medicines used in general anaesthetics (Ex. adrenaline, ephedrine, isoprenaline, noradrenaline)
  • medicines used in antihypertensive therapies (Ex. guanethidine, betanidine, reserpine and clonidine)
  • anticholinergic agents (Ex. darifenacin) (used to treat symptoms of overactive bladder)  
  • medicines used to treat mental illness (Ex. lithium), parkinson’s disease (Ex. levodopa)

Overdosage:

If you or anyone else accidentally take too much of FLEBIXEN PLUS 0.5, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are excessive sleepiness, irritability, agitation, hallucinations, dilated pupils, fast or irregular heartbeat, cardiac failure, low blood pressure, cardiogenic shock, urinary retention, mucosal dryness, intestinal hypomotility (infrequent bowel movements), convulsions, fever, depressed level of consciousness, coma, respiratory depression, metabolic acidosis (serious electrolyte imbalance), and low potassium levels.

SYNOPSIS

Drug :  

Flupenthixol, Melitracen

Pharmacological Category :  

Antipsychotics, Tricyclic antidepressants

Therapeutic Indication :  

Certain types of asthenia, depression and anxiety

Dosage Forms :  

Tablet

MORE INFORMATION

  • Keep FLEBIXEN PLUS 0.5 out of reach of children
  • Store at room temperature

FAQs ABOUT FLEBIXEN PLUS 0.5

Can FLEBIXEN PLUS 0.5 cause altered concentration?

Yes, FLEBIXEN PLUS 0.5 may cause altered concentration and attention. Therefore, it is advised not to drive or operate any machines or tools till you feel normal again after taking FLEBIXEN PLUS 0.5.

Is FLEBIXEN PLUS 0.5 safe for pregnant and breast-feeding women?

FLEBIXEN PLUS 0.5 is not recommended for use in pregnant women unless clearly advised by the doctor. It should be used with caution in breastfeeding women as it can pass through breast milk. The breast-fed infant should be kept under observation especially during first 4 weeks after being born. Consult your doctor before taking it.

Can FLEBIXEN PLUS 0.5 be given to children?

No, FLEBIXEN PLUS 0.5 is not recommended for use in children and adolescents (below 18 years of age). Child’s doctor may prescribe the alternate treatment for your child depending upon the condition.

Can FLEBIXEN PLUS 0.5 cause dizziness or drowsiness?

FLEBIXEN PLUS 0.5 may cause dizziness or drowsiness or may cause you to suddenly fall asleep during your daily activities. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medication affects you.

Is FLEBIXEN PLUS 0.5 safe to use in patients with heart disease?

FLEBIXEN PLUS 0.5 is not recommended for use in patients having heart diseases such as recent myocardial infarction (heart attack), any degree of heart block, disorders of cardiac rhythm and coronary artery insufficiency. Consult your doctor before taking FLEBIXEN PLUS 0.5.

REFERENCES

1. KD. Tripathi. Drugs Used in Mental Illness: Antipsychotic and Antimanic Drugs. Seventh edition. 2013. Page – 441.

2. Flupenthixol. NIH. National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in July 2022] [Accessed on 7th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/cis-Flupentixol#section=MeSH-Pharmacological-Classification

3. Melitracen. NIH. National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in July 2022]  [Accessed on 7th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Melitracen#section=Pharmacology-and-Biochemistry

4. Lynn Gers, Mirko Petrovic, Stany Perkisas, and Maurits Vandewoude. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. [Revised in May 2018]  [Accessed on 7th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199683/

5. C.G. Papaloisou Ltd. Deanxit. [Revised in August 2020]. [Accessed on 7th June 2022] https://www.papaloizou.com/PublicDocsPDF/SPCs/Deanxit_SPC.pdf

PRODUCT DETAILS

    Country Of Origin
    India
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