INTRODUCTION

FIXIMAX O SUSPENSION is a combination of Cefixime and Ofloxacin which belong to the group of medicines called Antibiotics. It is used in children to treat bacterial infections of the eyes, nose, throat, ears, bone, joints, skin, lungs, digestive tract and urinary tract.

FIXIMAX O SUSPENSION is also used to treat typhoid fever in children and adolescents, community acquired Pneumonia (lung infection acquired outside the hospital), fever of unknown origin and post-surgical infections.

FIXIMAX O SUSPENSION is intended for use in children so, contact your doctor before taking it during pregnancy or breastfeeding. It should not be taken with dairy products such as milk, yogurt and calcium- fortified foods such as cereal juices etc. Contact your physician if you experience any unusual side effects or if any of the symptoms deteriorate.

USES OF FIXIMAX O SUSPENSION

Treats:

• eyes, nose, throat, ears, bone, joints, skin, lungs, digestive tract and urinary tract infections
• typhoid fever in children and adolescents
• community acquired Pneumonia
• fever of unknown origin
• post-surgical infections

HOW FIXIMAX O SUSPENSION WORKS

FIXIMAX O SUSPENSION reduces bacterial infection where cefixime acts by breaking bacterial cell wall and ofloxacin stops bacterial cell multiplication.

DIRECTIONS FOR USE

Take FIXIMAX O SUSPENSION as advised by your physician. Reconstitute the dry powder with the liquid. Shake well before use. It is better to take FIXIMAX O SUSPENSION at the same fixed time every day. Try to drink more water as it will keep the kidney hydrated and help FIXIMAX O SUSPENSION work properly.

Dose and duration of FIXIMAX O SUSPENSION treatment will be decided by your physician depending upon your age, body weight and disease condition. Do not stop taking FIXIMAX O SUSPENSION unless your doctor advises you to stop.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions:

Before taking FIXIMAX O SUSPENSION, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicine.

B. Drug-Food Interactions:

FIXIMAX O SUSPENSION should not be taken with dairy products such as milk, yogurt and calcium- fortified foods such as cereal juices etc.

Overdosage:

If you or anyone else accidentally take too much of FIXIMAX O SUSPENSION, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose include diarrhea, abnormal stools, fever, dizziness and decreased appetite.

SYNOPSIS

MORE INFORMATION

• Keep FIXIMAX O SUSPENSION out of sight and reach of children
• Store FIXIMAX O SUSPENSION at 25°C

FAQs ABOUT FIXIMAX O SUSPENSION

Can the use of FIXIMAX O SUSPENSION cause diarrhoea?

Yes, the use of FIXIMAX O SUSPENSION may result in diarrhoea in children. While killing the harmful bacteria, it also damages the beneficial bacteria in the stomach or intestine and causes diarrhoea. If your child experiences diarrhoea, contact the doctor.

Is FIXIMAX O SUSPENSION safe for children?

Yes, FIXIMAX O SUSPENSION is safe to use in children and adolescents. Consult your child’s doctor for advice. The doctor will decide an appropriate dose or select a suitable alternative treatment for your child.

When is the best time to take FIXIMAX O SUSPENSION?

Take FIXIMAX O SUSPENSION regularly everyday according to the doctor’s advice. It is better to give this medicine to the baby at the same fixed time every day.

Can FIXIMAX O SUSPENSION be stopped once my child starts feeling better?

Even if the child starts to feel better, do not miss any doses of FIXIMAX O SUSPENSION and complete the entire course of treatment as prescribed by the doctor. Stopping the medicine too soon may cause the infection to return and become harder to cure.

What if I give FIXIMAX O SUSPENSION to my child even if he/she does not have any infection?

Avoid using FIXIMAX O SUSPENSION if it is not required to do so because excessive use could make the bacteria resistant to the treatment. Consult your doctor for further advice.

What if I forget to give a dose of FIXIMAX O SUSPENSION?

If you forget to give a dose of FIXIMAX O SUSPENSION to your child, give it as soon as you remember. However, omit the missed dose if it's almost time for the next one. Do not give the medicine two times to make up for the missed dose.

REFERENCES

1. KD. Tripathi. Antimicrobial drugs. Essentials of Medical Pharmacology. Eighth edition. 2019. Page – 763, 778.

2. Tiwaskar M. Cefixime-ofloxacin Combination in the Management of Uncomplicated Typhoid Fever in the Indian Community Setting. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. March 2019. [Accessed on 6th October 2022] https://pubmed.ncbi.nlm.nih.gov/31304712/

3. Bakthavatchalam YD, Kumar DT, Tayubi IA, et al. In vitro efficacy and in silico analysis of cefixime-ofloxacin combination for Salmonella Typhi from bloodstream infection. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. September 2017. [Accessed on 6th October 2022] https://pubmed.ncbi.nlm.nih.gov/28650129/

4. Leeford Pharmaceuticals. Zefway-O (Cefixime 50 mg + Ofloxacin 50 mg). [Accessed on 6th Oct 2022] https://www.leeford.in/product/423/zefway-o-dry-syrup

5. Leeford Pharmaceuticals. Cefitaxe-O (Anhydrous Cefixime 50 mg + Ofloxacin 50 mg). [Accessed on 6th Oct 2022] https://www.leeford.in/product/259/cefitaxe-o-dry-syrup

6. Pax Healthcare. Crinux-O Dry syrup (Cefixime 50 mg + Ofloxacin 50 mg). [Accessed on 6th Oct 2022] https://www.paxhealthcare.com/product/cefixime-50-mg-ofloxacin-50-mg-5-ml

7. Integrated Laboratories. Sefliv-OF (Cefixime 50 mg + Ofloxacin 50 mg). [Accessed on 6th Oct 2022] https://integratedlaboratories.in/cefixime-ofloxacin-dry-syrup-sefliv-of/

8. Alaina Pharma. Dixim-O (Cefixime 50 mg + Ofloxacin 50 mg). [Accessed on 6th Oct 2022] https://alainapharma.com/56.html

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count (CBC)
• WIDAL test