INTRODUCTION

FINCAR 5MG contains Finasteride which belongs to a group of medicines called type II 5-alpha reductase inhibitors. It is used to treat benign prostatic hyperplasia (BPH) which is a condition in which an overgrowth of prostate tissue pushes against the urethra and the bladder, blocking the flow of urine. It can also cause kidney, urinary tract or bladder problems.

Finasteride helps in shrinking of the prostate gland in adult men when it is swollen. DHT is considered to be the primary androgen playing an important role in the development and enlargement of prostate gland. Finasteride inhibits an isozyme called Type II 5α-reductase present in the prostate, seminal vesicles and epididymides, which is responsible for conversion of testosterone into 5alpha-dihydrotestosterone (DHT).

This medicine is intended for use only in men. It can be taken with or without food. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results. Talk to your doctor, before taking this medicine if you have any mood alterations and depression. Women planning to become pregnant or already pregnant should avoid exposure to the drug through sexual contact with a man taking finasteride and should not touch crushed or broken tablets of finasteride. This medicine is strictly not recommended for use in children.

USES OF FINCAR 5MG

• Benign prostatic hyperplasia (enlarged prostate)

HOW FINCAR 5MG WORKS

DHT is considered to be the primary androgen playing an important role in the development and enlargement of prostate gland. Finasteride specifically inhibits an isozyme called Type II 5α-reductase present in the prostate, seminal vesicles and epididymides, which is responsible for conversion of testosterone into 5alpha-dihydrotestosterone (DHT).

Inhibition of Type II 5α-reductase by finasteride, blocks the peripheral conversion of testosterone to DHT, resulting in a significant decrease in serum and tissue DHT concentrations, increase in prostatic testosterone concentration and decrease in prostatic volume.

DIRECTIONS FOR USE

Always take this medicine as directed by your physician. The recommended dosage is one tablet per day. Your doctor will decide the correct dose for you depending upon your condition. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF FINCAR 5MG

WARNING & PRECAUTIONS

INTERACTIONS

Inform your doctor about all the medicines you use, including prescription and non-prescription medicines, and herbal supplements.

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT FINCAR 5MG

Is FINCAR 5MG a steroid drug?

Yes.  It is an analogue of androgen steroid hormones like testosterone and DHT.

Can FINCAR 5MG cause erectile dysfunction?

Yes. Infertility has been reported in men taking finasteride for long time. However, this can be reversed once treatment has been discontinued.

REFERENCES

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page – 302-303.

2. Peter J. Snyder. Androgens. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1205.

3. Merck Sharp & Dohme Corp. Comparison of Finasteride and Tamsulosin for Treatment of Benign Prostatic Hyperplasia (BPH) (MK-0906A-149 AM2). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on August 2018 [Accessed 17th November 2020] https://clinicaltrials.gov/ct2/show/NCT01534351

4. Jayne E Edwards and R Andrew Moore. Finasteride in the treatment of clinical benign prostatic hyperplasia: A systematic review of randomised trials. NCBI; PMC US National Library of Medicine, National Institute of Health. December 2002. [Accessed 17th November 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140032/#:~:text=and%20previous%20interventions.-,Results,flow%20rate%2C%20and%20prostate%20volume

5. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC); [Revised on August 2018] [Accessed 17th November 2020] https://www.medicines.org.uk/emc/files/pil.3493.pdf

6. Cipla (EU) Limited. Electronic Medicines Compendium (EMC); [Revised on July 2020] [Accessed 17th November 2020] https://www.medicines.org.uk/emc/files/pil.9958.pdf

USEFUL DIAGNOSTIC TESTS

• Prostate-specific antigen (PSA) blood test
• Prostate magnetic resonance imaging (MRI)
• Urine flow study
• Digital rectal examination
• Cystoscopy