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INTRODUCTION
FILRON XT TABLET contains Ferrous ascorbate and Folic acid which belongs to the group of medicines called Hematinics. It is used to treat and prevent nutritional deficiency anaemia associated with iron and folic acid.
FILRON XT TABLET can also be used to treat and prevent anaemia occurring during pregnancy and breast feeding. Anemia is when your body can't produce enough of haemoglobin (a substance in red blood cells that enables them to carry oxygen), due to insufficient iron.
FILRON XT TABLET is not recommended to be taken if you have any kidney or liver diseases, porphyria cutanea tarda, conditions affecting iron level of your body, cobalamin deficiency, any malignant disease, inflammatory bowel disease, galactose intolerance, lapp lactase deficiency or glucose - galactose malabsorption.
It is not recommended to take FILRON XT TABLET if you are receiving frequent blood transfusions and parenteral iron therapy. FILRON XT TABLET is safe to take in pregnancy and breastfeeding, however, consult your doctor before taking it. Safety and efficacy of FILRON XT TABLET in children have not been established.
The most common side effects of taking FILRON XT TABLET are nausea, vomiting, constipation, diarrhoea and dark stools. It is recommended to consult the doctor if any of the symptoms worsen or persist for longer duration.
USES OF FILRON XT TABLET
Treats and prevents anaemia occurring:
- due to deficiency of iron and folic acid
- during pregnancy and breastfeeding
HOW FILRON XT TABLET WORKS
FILRON XT TABLET helps increase haemoglobin levels where Ferrous ascorbate facilitates oxygen delivery and consumption, promotes cell growth and multiplication and thus boosts red blood cells and haemoglobin synthesis and Folic acid plays an essential role in the production of red blood cells (which transport oxygen throughout the body) and during pregnancy, owing to its function in the development of the brain and spinal cord of the developing baby.
DIRECTIONS FOR USE
Take FILRON XT TABLET as advised by your physician. Swallow it with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of FILRON XT TABLET treatment depending upon your age, body weight and disease condition.
SIDE EFFECTS OF FILRON XT TABLET
COMMON
- nausea, vomiting
- constipation, diarrhea
- dark stools
RARE
- loss of appetite, flatulence, swollen abdomen
- allergic reactions (redness, rash, itching, hives, breathlessness or shock)
HOW TO MANAGE SIDE EFFECTS
Nausea:
Take FILRON XT TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If symptom persists, contact your doctor.
Vomiting:
Get adequate rest. Drink lots of fluids, especially water. Have small sips if you feel sick. Eat when you feel like it – you don't have to eat or avoid any specific foods. Do not take any medicine for vomiting without your doctor's consultation. If vomiting persists, contact your doctor.
Diarrhea:
Drink lots of liquids like water or fruit juice to maintain hydration. Call your doctor before taking any medicine for diarrhea. If diarrhea persists, contact your doctor.
Constipation:
Consume enough fiber rich foods like fresh fruits, vegetables, cereals and drink ample amount of water. Exercise more regularly. If symptom persists, contact your doctor.
Loss appetite:
Eat when you are hungry. Eat smaller meals more often than usual. Snack only when you're hungry. Eat a protein-rich or other healthy snack such as dried fruit and nuts. If appetite does not get better, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
FILRON XT TABLET should be taken by pregnant women only if necessary. Consult your doctor before taking it.
BREASTFEEDING
FILRON XT TABLET should be taken during breastfeeding only if the potential benefits outweigh the potential risks to the baby. Consult your doctor before taking it.
ALCOHOL
FILRON XT TABLET should be used with caution in patients who consume alcohol in large amounts. Consult your doctor for advice.
KIDNEY
FILRON XT TABLET should be used with caution in patients with a history of kidney disease. Consult your doctor before taking it.
LIVER
FILRON XT TABLET should be used with caution in patients with hepatitis (inflammation of liver). Consult your doctor before taking it.
ALLERGY
Do not take FILRON XT TABLET if you are allergic to ferrous ascorbate, folic acid or any of the other ingredients of this medicine.
HEART DISEASE
FILRON XT TABLET should be used with caution in patients with a family history of heart diseases. Consult your doctor before taking it.
OTHERS
FILRON XT TABLET is not recommended for use if you:
- have porphyria cutanea tarda (a rare disease characterized by painful blister-like skin lesions that develop on the skin exposed to sun)
- have conditions characterized by increased amount of iron level in body (Ex. haemochromatosis and hemosiderosis)
- have haemolytic anaemia (increased rate of destruction of red blood cells as compared to the rate of formation of red blood cells)
- have untreated cobalamin deficiency
- have Addisonian pernicious anaemia (drop in red blood cells when the body can't absorb enough vitamin B12)
- have any malignant diseases
- are receiving repeated blood transfusions
- have anaemias not produced by iron deficiency
- are receiving parenteral iron therapy
- have gastrointestinal diseases (Ex. inflammatory bowel disease, intestinal strictures and diverticulae)
- have galactose intolerance, lapp lactase deficiency or glucose - galactose malabsorption (rare hereditary problems)
Before taking FILRON XT TABLET, inform your doctor if you:
- have folate-dependent tumors
- have intestinal disease
- have peptic ulcers
- have inflammation of intestine, colon or pancreas
- are undergoing angioplasty (surgery to stretch open a narrowed or blocked artery)
Use in Pediatrics:
Safety and efficacy of FILRON XT TABLET in children have not been established. Consult your child’s doctor for advice.
Use in Geriatrics:
FILRON XT TABLET should be used with caution in elderly patients (over 55 years of age). Consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug Interactions:
Before taking FILRON XT TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to treat acidity (Ex. magnesium hydroxide, sodium bicarbonate, aluminium carbonate)
- calcium, zinc, vanadium (used as mineral supplements)
- medicines used to treat bacterial infections (Ex. ciprofloxacin, methacycline, minocycline, cefdinir, ciprofloxacin, moxifloxacin, ofloxacin, acetohydroxamic acid, demeclocycline, co-trimoxazole)
- levothyroxine (used in thyroid conditions)
- trientine, penicillamine (used to treat Wilson’s disease)
- medicines used to treat stomach ulcers (Ex. esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole)
- medicines used to control cholesterol levels (Ex. cholestyramine, colestipol)
- pancrelipase (used to improve food digestion)
- medicines used in bone problems (Ex. risedronate, alendronate, ibandronate)
- medicines used in Parkinson’s disease (Ex. entacapone, levodopa, methyldopa)
- mycophenolate mofetil (used to suppress immune system)
- ascorbic acid and citric acid (used as antioxidants)
- dimercaprol (used to treat arsenic or mercury toxicity)
- medicines used to treat fits (Ex. phenytoin, phenobarbital, primidone)
- sulfasalazine (used to treat inflammatory bowel diseases)
- methotrexate (used in cancer treatment)
B. Drug- Food Interactions:
Avoid consuming foods containing soybean or soy protein with FILRON XT TABLET as they can reduce iron absorption.
Overdosage:
If you or anyone else accidentally take too much of FILRON XT TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are stomach pain, nausea, vomiting, diarrhoea, dark sticky stools, blood in vomit, low blood pressure, fast heartbeat, dehydration, drowsiness, paleness, bluish discoloration, tiredness and fits.
SYNOPSIS
| Drug | : | Ferrous ascorbate, Folic acid |
| Pharmacological Category | : | Vitamins and Minerals |
| Therapeutic Indication | : | Anemia |
| Dosage Forms | : | Tablet, capsule, oral drops, syrup, suspension, syringe |
MORE INFORMATION
- Keep FILRON XT TABLET out of reach of children
- Store FILRON XT TABLET below 25°C
FAQs ABOUT FILRON XT TABLET
Can FILRON XT TABLET be given to children?
Safety and efficacy of FILRON XT TABLET in children have not been established. Consult your child’s doctor for advice. The doctor will determine an appropriate dose or select a suitable alternative treatment for your child.
What if I forget to take a dose of FILRON XT TABLET?
If you forget to take a dose of FILRON XT TABLET, take it as soon as you remember. However, omit the missed dose if it's almost time for the next one. Do not take FILRON XT TABLET two times to make up for the missed dose.
Can I stop taking FILRON XT TABLET on my own?
Continue taking FILRON XT TABLET until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. Contact your doctor in such case.
How should FILRON XT TABLET be taken? Can it be crushed?
No. Do not break, crush or chew FILRON XT TABLET. Take it as advised by your physician. Swallow it with a glass of water. Your doctor will decide the correct dose and duration of FILRON XT TABLET for you based on your age, body weight and disease condition.
Can I take FILRON XT TABLET if I recently received a coronary stent?
No, it is not recommended to take FILRON XT TABLET if you got a surgery performed for coronary stenosis (angioplasty and coronary stents). Also, it is recommended to take FILRON XT TABLET with caution if anyone in the family is diagnosed with a condition/ disease affecting heart. Consult your doctor for advice.
REFERENCES
1. Sean C Sweetman. Nutritional Agents and Vitamins. Martindale The Complete Drug Reference. 36th edition. Page- 1938, 1940.
2. Malhotra N, Kriplani A, Pal B, et al. Ferrous Ascorbate: Current Clinical Place of Therapy in the Management of Iron Deficiency Anemia. J South Asian Feder Obst Gynae. 2021. [Accessed on 18th October 2022] https://www.jsafog.com/doi/JSAFOG/pdf/10.5005/jp-journals-10006-1896
3. Yakoob, M.Y., Bhutta, Z.A. Effect of routine iron supplementation with or without folic acid on anemia during pregnancy. Journal of Rare Diseases. SpringerLink. April 2011. [Accessed on 18th October 2022] https://link.springer.com/article/10.1186/1471-2458-11-S3-S21#citeas
4. Cipla Ltd. HB- Set (Ferrous ascorbate + Folic acid). [Revised in December 2015] [Accessed on 18th October 2022] https://www.ciplamed.com/content/hb-set-tablets
5. Alkem Labortaries Ltd. HemFer- XT (Ferrous ascorbate + Folic acid). [Revised in June 2016] [Accessed on 18th October 2022] https://www.alkemlabs.com/pdf/adverse/HEMFER%20XT.pdf
6. Micro Labs Ltd. Biofer-XT Tablets (Ferrous ascorbate + Folic acid). [Accessed on 18th October 2022] https://www.microlabsltd.com/elibrary/node/1545
7. Neuracle Lifesciences. Irogud XT (Ferrous ascorbate + Folic acid). [Accessed on 18th October 2022] https://www.neuraclelife.com/product/ferrous-ascorbate-folic-acid-tablet/
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count (CBC)
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