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FILIXIM PLUS Tablet 10's
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INTRODUCTION
FILIXIM PLUS TABLET is a combination of Cefixime and Lactobacillus which belongs to the group of medicines called Antibiotics and Probiotics respectively. FILIXIM PLUS TABLET is used in the treatment of bacterial infections like tonsillitis, pharyngitis, pneumonia, bronchitis & other respiratory tract infections, skin & soft tissue infections and urinary tract infections. Lactobacillus is used to prevent diarrhoea associated with the intake of cefixime.
Before taking FILIXIM PLUS TABLET, inform your doctor if you have swelling or inflammation of the large intestine (colon), kidney impairment, intestinal damage, had bowel surgery recently and if you are allergic to other cephalosporin antibiotics including penicillin.
FILIXIM PLUS TABLET should be used with caution in pregnant women and it is not recommended for use in breastfeeding women. FILIXIM PLUS TABLET is not recommended for use in children under 10 years of age and it should be used with caution in elderly patients (aged 65 years and above).
The common side effects of taking FILIXIM PLUS TABLET are nausea, vomiting, indigestion and headache. Consult with your doctor if any of the side effects worsen.
USES OF FILIXIM PLUS TABLET
Treats:
- tonsillitis
- pharyngitis
- pneumonia
- bronchitis & other respiratory tract infections
- skin & soft tissue infections
- urinary tract infections
HOW FILIXIM PLUS TABLET WORKS
FILIXIM PLUS TABLET is a combination of Cefixime and Lactobacillus. Cefixime works against both gram-positive and gram-negative organisms. It acts by inhibiting bacterial cell wall synthesis, which is essential for the survival of bacteria in the human body. It inhibits transpeptidase (bacterial enzyme) and prevents the cross linking of bacterial cell wall, resulting in killing of bacteria. Lactobacillus acts as a probiotic, which is used along with antibiotic to restore the body`s natural microbial flora within the digestive tract. It inhibits or decreases the growth of harmful microorganisms in the gut by producing lactic acid. This collective action is useful in treating infections caused by bacteria.
DIRECTIONS FOR USE
Take FILIXIM PLUS TABLET as advised by your physician. It can be taken with or without food.
For Tablet: Swallow FILIXIM PLUS TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.
SIDE EFFECTS OF FILIXIM PLUS TABLET
COMMON
- nausea, vomiting
- indigestion
- headache
RARE
Stop taking FILIXIM PLUS TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (signs include skin rash, severe itching of the skin with raised lumps, blisters in the skin, swelling of the face, lips, tongue and/or throat with difficulty in breathing or swallowing)
- severe skin problems such as toxic epidermal necrolysis (TEN), stevens-johnson syndrome (SJS), (signs include blistering, peeling or bleeding on any part of the skin including the lips, eyes, mouth, nose, genitals, hands or feet. Also, flu-like symptoms such as fever, chills or aching muscles) and acute generalised exanthematous pustulosis (AGEP) (signs include red, scaly, widespread rash with bumps under the skin including your skin folds, chest, abdomen (including stomach), back and arms) and blisters accompanied by fever)
- drug rash with eosinophilia and systemic symptoms (DRESS) (signs include flu-like symptoms and a widespread rash with a high body temperature and enlarged lymph nodes)
- severe watery diarrhoea that will not stop and you are feeling weak and have a fever, this may be something called ‘pseudomembranous colitis’
- get infections more easily than usual
- bruise or bleed more easily than normal
- nose bleeds, bleeding gums, chills, tiredness, pale skin (often with a yellow tinge), shortness of breath
- blood in urine
- fits (convulsions)
- brain condition with symptoms including fits (convulsions), feeling confused, feeling less alert or aware of things than usual, unusual muscle movements or stiffness
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Drink lot of fluids such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.
Nausea And Vomiting
Take this medicine with or immediately after food. Stick to simple meals. Avoid eating oily, fried and spicy foods. Do not perform any strenuous activities immediately after eating. Consult your doctor if the symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
Use with CautionFILIXIM PLUS TABLET should be used with caution in pregnant women. Consult your doctor before taking FILIXIM PLUS TABLET.
BREASTFEEDING
ContraindicatedFILIXIM PLUS TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking FILIXIM PLUS TABLET.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate any machines if you experience fits, confusion, feeling less alert or aware of things than usual, unusual muscle movements or stiffness after taking FILIXIM PLUS TABLET.
ALCOHOL
Consult your doctorAvoid consumption of alcohol while taking FILIXIM PLUS TABLET because it might make you dizzier.
KIDNEY
Use with CautionFILIXIM PLUS TABLET should be used with caution in patients with impaired kidney function. Consult your doctor before taking FILIXIM PLUS TABLET.
ALLERGY
ContraindicatedDo not take FILIXIM PLUS TABLET if you are allergic to cefixime, any other cephalosporin antibiotics including penicillin.
OTHERS
FILIXIM PLUS TABLET is not recommended for use if you:
- have colitis (swelling or inflammation of the large intestine)
- have weakened immune system
- have intestinal damage
- had bowel surgery recently
Use in paediatrics:
FILIXIM PLUS TABLET should be used with caution in children over 10 years of age or weighing more than 50 kg. Consult your child’s for advice.
Use in geriatrics:
FILIXIM PLUS TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking FILIXIM PLUS TABLET.
INTERACTIONS
A. Drug-Drug interactions:
Before taking FILIXIM PLUS TABLET, inform your doctor if you are taking any of the following medicines:
- salicylates such as aspirin (used to treat fever and pain)
- probenecid (used to prevent and treat gout)
- warfarin (used to prevent or treat blood clots)
- insulin (used to treat diabetes mellitus)
Overdosage:
If you or anyone else accidentally takes too much of FILIXIM PLUS TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of FILIXIM PLUS TABLET are blood in the urine, diarrhea, nausea, upper abdominal pain and vomiting.
SYNOPSIS
| Drug | : | Cefixime, Lactobacillus |
| Pharmacological Category | : | Cephalosporin antibiotics, Probiotics |
| Therapeutic Indication | : | Various bacterial infections |
| Dosage Forms | : | Tablet, Capsule, Dispersible tablet, Dry suspension, Dry syrup,Oral suspension, Powder, Rediuse, Syrup |
MORE INFORMATION
- Keep FILIXIM PLUS TABLET out of reach of children
- Store FILIXIM PLUS TABLET at room temperature
FAQs ABOUT FILIXIM PLUS TABLET
Q: What is FILIXIM PLUS TABLET and why is it prescribed?
A: FILIXIM PLUS TABLET is a combination of Cefixime and Lactobacillus which belongs to the group of medicines called Antibiotics and Probiotics respectively. FILIXIM PLUS TABLET is used in the treatment of bacterial infections like tonsillitis, pharyngitis, pneumonia, bronchitis & other respiratory tract infections, skin & soft tissue infections and urinary tract infections. Lactobacillus is used to prevent diarrhoea associated with the intake of cefixime.
Q: What are the common side effects of FILIXIM PLUS TABLET?
A: The most common side effects of taking FILIXIM PLUS TABLET are nausea, vomiting, indigestion and headache. Consult with your doctor if any of the side effects worsen over the time.
Q: Is FILIXIM PLUS TABLET safe to use in patients with kidney problems?
A: FILIXIM PLUS TABLET should be used with caution in patients with impaired kidney function. Your doctor may monitor your kidney function during and after treatment with this medicine to prevent the risk of any unusual effects. Consult your doctor before taking it.
Q: What happens if I accidentally take extra dose of FILIXIM PLUS TABLET?
A: If you or anyone else accidentally takes too much of FILIXIM PLUS TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of FILIXIM PLUS TABLET are blood in the urine, diarrhea, nausea, upper abdominal pain and vomiting.
Q: Can FILIXIM PLUS TABLET be used in pregnant and breast-feeding women?
A: FILIXIM PLUS TABLET should be used with caution in pregnant women and it is not recommended for use in breastfeeding women. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breast-feeding your baby.
REFERENCES
1. KD. Tripathi. Antimicrobial drugs General Considerations Essentials of medica pharmacology. seventh edition. 2017. Page – 687 & 703.
2. Song HJ, Kim JY, Jung SA, Kim SE, Park HS, Jeong Y, Hong SP, Cheon JH, Kim WH, Kim HJ, Ye BD, Yang SK, Kim SW, Shin SJ, Kim HS, Sung JK, Kim EY. Effect of probiotic Lactobacillus for the prevention of antibiotic-associated diarrhoea: a prospective, randomized, double-blind, multicenter study. NIH National Library of Medicine, National center for biotechnology information. December 2010 [Accessed on 3rd June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995234/
3. University of Southern California. Cefixime Clinical Trial. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in June 2022] [Accessed on 3rd June 2022] https://clinicaltrials.gov/ct2/show/NCT04958122
4. Famar Lyon Ltd. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed on 3rd June 2022] https://www.medicines.org.uk/emc/files/pil.5534.pdf
5. Medicine India. Cefixime and Lactobacillus. [Accessed on 3rd June 2022] https://www.medicineindia.org/pharmacology-for-generic/357/cefixime-lactobacillus
USEFUL DIAGNOSTIC TESTS
- Complete blood count
AUTHOR DETAILS
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 28 Jan 2023 | 05:49 PM(IST)
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