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INTRODUCTION
FENTIWILL contains Fenticonazole which belongs to the group of medicines called Antifungals. It is used in adults and adolescents to treat genital candidiasis (fungal infection of the vagina and tissues at the opening of the vagina (vulva) that results in inflammation, intense itchiness, and a thick, white discharge from the vagina) and mixed vaginal infections (a change in the characteristics of vaginal discharge along with genital itching and burning pain).
Fenticonazole works by interfering with the fungi cell membrane by inhibiting the production of a substance called ergosterol (a type of fat that provides the ability to flow easily to the cell membrane). This type of action prevents the growth of the fungi by forming holes in the membrane and helps in treating vaginal fungal infections.
Before using FENTIWILL, inform your doctor if you have or ever had abnormal or irregular vaginal bleeding, blood staining in the vaginal discharge, vulval or vaginal sores, ulcers or blisters, lower abdominal pain or dysuria (painful or difficult urination), using a latex made contraceptive method and a history of a sexually transmitted disease or exposure to partner with the sexually transmitted disease. FENTIWILL is generally not recommended for use in pregnant and breastfeeding women unless clearly advised by your doctor. FENTIWILL is not recommended for use in children and adolescents (below 16 years of age) and it should be used with caution in adolescents (above 16 years of age) and elderly patients. Therefore, consult your doctor before using it. The most common side effects of using FENTIWILL are irritation, itching, and burning sensation. Contact your doctor for advice if any of the symptoms worsen.
USES OF FENTIWILL
- Treats genital candidiasis and mixed vaginal infections
HOW FENTIWILL WORKS
FENTIWILL works by interfering with the fungi cell membrane by inhibiting the production of a substance called ergosterol (a type of fat that provides the ability to flow easily to the cell membrane). This type of action prevents the growth of the fungi by forming holes in the membrane and helps treating vaginal fungal infections.
DIRECTIONS FOR USE
Apply FENTIWILL as advised by your physician. It is for vaginal use only. Wash your hands before use. Use the applicator provided for applying the cream into the vagina. To do this, the applicator is to be attached to the tube. Squeeze the cream into the applicator until it is full. Remove the applicator from the tube, and then gently insert the cream-filled end of the applicator into the vagina as high as it is comfortable for you. Push the plunger to release the cream into the vagina. Remove the applicator and wash it with warm water and soap, to ready for your next dose. The correct dose and duration will be decided by the doctor depending on your age, body weight, and disease condition.
SIDE EFFECTS OF FENTIWILL
COMMON
- mild irritation
- itching
- burning sensation
UNCOMMON
- eczema (skin becomes dry, red and itchy)
- skin exfoliation
- redness of skin
- edema
RARE
- signs of contact dermatitis (red rash wherever the skin comes in contact with the irritant)
Stop using FENTIWILL and contact your doctor immediately if you experience any of the following side effects:
- increased episodes of persistent skin irritation
- signs of hypersensitivity reactions (raised, itchy, red rash, swollen lips, tongue, eyes or face and shortness of breath)
HOW TO MANAGE SIDE EFFECTS
Itching:
Try using warm water and gentle cleanser to wash your genital area. Avoid using scented soaps, lotions, and bubble baths. Consult your doctor if the symptom does not improve.
WARNING & PRECAUTIONS
PREGNANCY
FENTIWILL is generally not recommended for use in pregnant women unless considered clearly necessary. It is not recommended for use in women of childbearing potential in those not using effective contraception. Consult your doctor before using FENTIWILL.
BREASTFEEDING
FENTIWILL is generally not recommended for use in breastfeeding women unless considered clearly necessary. Consult your doctor before using FENTIWILL.
DRIVING AND USING MACHINES
FENTIWILL has no influence on the ability to drive and use machines.
ALLERGY
Do not use FENTIWILL if you are allergic to Fenticonazole or other Imidazoles (such as clotrimazole) or other vaginal antifungal products.
OTHERS
Before using FENTIWILL, inform your doctor if you:
- have the infection for the first time
- still have the symptoms after 7 days or if you feel worse
- had more than 4 previous infections within last year
- or your partner have ever had a sexually transmitted disease
- have abnormal or irregular vaginal bleeding
- have blood staining of a vaginal discharge
- have vulval or vaginal sores, ulcers, or blisters
- have lower abdominal pain, back pain, or dysuria (painful or difficult urination)
- have fever, nausea and malodorous discharge
Use in pediatrics:
FENTIWILL is generally not recommended for use in children and adolescents (below 16 years of age). It should be used with caution in adolescents (above 16 years of age). Therefore, consult your doctor before using it.
Use in geriatrics:
FENTIWILL should be used with caution in elderly patients (aged 60 years or above). Contact your doctor before using FENTIWILL.
INTERACTIONS
A. Drug-Drug Interaction:
Before using FENTIWILL, inform your doctor if you are using latex made barrier contraceptives, spermicides, intravaginal douches, and other vaginal products.
Overdosage:
If you use more FENTIWILL than you should, consult your doctor for advice.
SYNOPSIS
| Drug | : | Fenticonazole |
| Pharmacological Category | : | Imidazole derivatives |
| Therapeutic Indication | : | Genital candidiasis and mixed vaginal infections |
| Dosage Forms | : | Vaginal Capsule, Cream |
MORE INFORMATION
- Keep FENTIWILL out of reach of children
- Store at a room temperature
FAQs ABOUT FENTIWILL
Is it safe to use FENTIWILL in children?
FENTIWILL is generally not recommended for use in children and adolescents (below 16 years of age). It should be used with caution in adolescents (above 16 years of age). Therefore, consult your doctor before using it.
Can I stop using FENTIWILL if my condition improves?
Do not stop using FENTIWILL without contacting your physician. Remember to complete the course of treatment as this will help to prevent the infection from coming back even if you feel your condition is improved. Contact your doctor if the symptoms do not improve after using FENTIWILL.
What is FENTIWILL used for?
FENTIWILL is used to treat genital candidiasis (fungal infection of the vagina and tissues at the opening of the vagina (vulva) that results in inflammation, intense itchiness and a thick, white discharge from the vagina) and mixed vaginal infections (a change in the characteristics of vaginal discharge along with genital itching and burning pain) in adults and adolescents.
What precautions to be followed before using FENTIWILL?
Before using FENTIWILL, inform your doctor if you have or ever had abnormal or irregular vaginal bleeding, blood staining in the vaginal discharge, vulval or vaginal sores, ulcers or blisters, lower abdominal pain or dysuria (painful or difficult urination), and a history of sexually transmitted disease or exposure to partner with the sexually transmitted disease. Consult your doctor for advice before using FENTIWILL.
How does FENTIWILL work?
FENTIWILL works by interfering with the cell membrane of the fungi by inhibiting the production of a substance called ergosterol. Thereby, preventing the growth of the fungi by forming holes in the membrane and as a result it helps to treat vaginal fungal infections.
REFERENCES
1. Kubra Saygisever-Faikoglu, Gokhan Faikoglu, Fatmanur Otmar Ozcan, Tugce Uskur, Dundar Okan Yillar, Barkin Berk, Pelin Kelicen Ugur. The efficacy and safety of fenticonazole in the treatment of mixed vaginitis. Pharmacy & Pharmacology International Journal. January 2022. [Accessed on 30th June 2022] https://medcraveonline.com/PPIJ/the-efficacy-and-safety-of-fenticonazole-in-the-treatment-of-mixed-vaginitis.html
2. Stefano Veraldi, Rodolfo Milani. Topical fenticonazole in dermatology and gynaecology: current role in therapy. NIH. National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2008 [Accessed on 30th June 2022] https://pubmed.ncbi.nlm.nih.gov/18840006/
3. J Fernandez-Alba, A Valle-Gay, M Dibildox, J A Vargas, J Gonzalez, M Garcia, L H Lopez. Fenticonazole nitrate for treatment of vulvovaginitis: efficacy, safety, and tolerability of 1-gram ovules, administered as ultra-short 2-day regimen. Journal of Chemotherapy. April 2004. [Accessed on 30th June 2022] https://pubmed.ncbi.nlm.nih.gov/15216954/
4. Recordati Industria Chimica e Farmaceutica S.p.A. Gynoxin Vaginal Cream. [Revised in March 2020] [Accessed on 30th June 2022] http://recordati.pl/produkty_upload/gynoxin_krem_dopochwowy/File/Gynoxin_cream_leaflet.pdf
5. Recordati Industria Chimica e Farmaceutica SpA. Health Products Regulatory Authority (HPRA) [Revised in January 2010] [Accessed on 30th June 2022] https://www.hpra.ie/img/uploaded/swedocuments/LicenseSPC_PA0812-002-001_30012010225621.pdf
6. Leeford pharmaceuticals limited. Fenzitop Cream [Accessed on 30th June 2022] https://www.leeford.in/product/1495/fenzitop-cream
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.