FEBULIFE 40 Tablet 10's

Gout Rx required

Best Price* ₹ 79.60 MRP ₹ 99.50
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Renauxe Pharma India Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

FEBULIFE 40 TABLET contains Febuxostat, which belongs to a group of medicines called Antigout agents. It is used in the treatment of gout (common and complex form of arthritis that occurs when too much uric acid crystallises and deposits in the joints, resulting in sudden, severe attacks of pain, swelling, redness and tenderness in one or more joints, most often in the big toe). It is also used to prevent accumulation of high blood levels of uric acid in the blood.

Before taking FEBULIFE 40 TABLET inform your doctor if you have any liver, kidney, heart, thyroid problems and undergoing treatment for Lesch-Nyhan syndrome. FEBULIFE 40 TABLET is not recommended for use by pregnant women, breastfeeding mothers, children, and adolescents. FEBULIFE 40 TABLET should be used with caution by elderly patients.

The common side effects of taking FEBULIFE 40 TABLET are abnormal liver test results, diarrhoea, headache, rash, nausea, increase in gout symptoms, localized swelling due to retention of fluids in tissues (oedema). Consult your doctor immediately if any of your symptoms gets worse.

USES OF FEBULIFE 40 TABLET

  • Treats gout
  • Prevents accumulation of high uric acid levels in the blood

HOW FEBULIFE 40 TABLET WORKS

FEBULIFE 40 TABLET works by blocking the action of enzyme called xanthine oxidase, which is involved in the process of converting hypoxanthine into uric acid (purine metabolism pathway). This type of action reduces high uric acid level in gout and blood cancer patients undergoing chemotherapy treatment.

DIRECTIONS FOR USE

Take FEBULIFE 40 TABLET as advised by your physician. Swallow FEBULIFE 40 TABLET with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight.

SIDE EFFECTS OF FEBULIFE 40 TABLET

COMMON

  • liver function test results appear abnormal
  • diarrhea
  • headache
  • skin rash
  • nausea
  • exaggerated gout symptoms
  • oedema

UNCOMMON

  • decreased appetite
  • signs of diabetes (blood sugar level changes, excessive thirst, increased blood fat levels and weight)
  • loss of sex drive
  • difficulty in sleeping
  • sleepiness
  • dizziness, numbness, tingling, reduced or altered sensation
  • altered taste sensation, decreased sense of smell
  • abnormal ECG, irregular or rapid heartbeats and palpitation
  • hot flushes (e.g., redness of the face or neck), increased blood pressure
  • cough, shortness of breath, chest discomfort or pain, inflammation of nasal passage and/or throat and bronchitis
  • dry mouth, abdominal pain or wind, heartburn, constipation, vomiting, stomach discomfort
  • skin itching, and small red or purple spots on the skin, covered with small confluent bumps, areas of redness and spots on the skin
  • inflammation of joints usually accompanied by pain, swelling and/or stiffness,
  • blood in the urine, abnormal frequent urination, abnormal urine tests (increased level of proteins in the urine)
  • fatigue, chest pain, chest discomfort
  • stones in gallbladder or bile ducts (cholelithiasis)
  • increase thyroid stimulating hormone (TSH) level
  • blood chemistry changes or abnormal amount of blood cells or platelets
  • kidney stones
  • erectile dysfunction

RARE

  • nervousness
  • feeling thirsty
  • ringing sensation in the ears
  • blurred vision, change in vision
  • hair loss
  • ulcers in mouth
  • increased sweating
  • weight decrease, increased appetite, or uncontrolled loss of appetite
  • muscle and/or joint stiffness
  • urgent need to urinate
  • changes or decrease in urine amount due to inflamed kidneys
  • inflamed liver, yellowing of the skin or liver damage
  • increased level of creatine phosphokinase in blood
  • sudden cardiac death

Stop taking FEBULIFE 40 TABLET and contact your doctor immediately if you experience any of the following side effects:

  • signs of Stevens- Johnson syndrome/ toxic epidermal necrolysis (serious skin rashes characterized by formation of blisters and shedding of the skin and inner surfaces of mouth and genitals, painful ulcers in the mouth and/or genital areas, accompanied by fever, sore throat, fatigue)
  • muscle pain, tenderness, or weakness
  • sings of drug reaction with eosinophilia and systemic symptoms (extensive skin rash in association with enlarged lymph nodes, liver enlargement, raising of the white cells count)

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Take FEBULIFE 40 TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. If the symptom does not improve, contact your doctor immediately.

Flatulence:

Eat smaller and more frequent meals. Eat and drink slowly, and exercise regularly. If the symptom does not improve, contact your doctor immediately.

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. If the symptom does not improve, contact your doctor immediately.

Diarrhoea:

Drink lots of fluids, such as water or fruit juice, to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor immediately.

WARNING & PRECAUTIONS

PREGNANCY

FEBULIFE 40 TABLET is generally not recommended for use by pregnant women. Consult your doctor before taking the medicine.

BREASTFEEDING

FEBULIFE 40 TABLET is generally not recommended for use by breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy, sleepy, blurred vision and numbness or tingling sensation after taking FEBULIFE 40 TABLET.

KIDNEY

FEBULIFE 40 TABLET should be used with caution in patients with having or have had kidney disease. Consult your doctor for advice before taking FEBULIFE 40 TABLET.

LIVER

FEBULIFE 40 TABLET should be used with caution in patients who have or had liver disease or liver function test abnormalities. Consult your doctor for advice before taking FEBULIFE 40 TABLET.

ALLERGY

FEBULIFE 40 TABLET is not recommended for use if you are allergic to febuxostat. It should also be used with caution in patients having history of serious allergic reaction to Allopurinol.

HEART DISEASE

FEBULIFE 40 TABLET should be used with caution in patients having or have had heart failure or heart problems or stroke. Consult your doctor for advice before taking FEBULIFE 40 TABLET.

OTHERS

Before taking FEBULIFE 40 TABLET, inform your doctor if you:

  • are being treated for Lesch-Nyhan syndrome
  • have thyroid problems

Use in Paediatrics:

FEBULIFE 40 TABLET is generally not recommended for use in children and adolescents (under 18 years of age). Consult your doctor before taking FEBULIFE 40 TABLET.

Use in Geriatrics:

FEBULIFE 40 TABLET should be used with caution in elderly patients. Consult your doctor for advice before taking FEBULIFE 40 TABLET.

INTERACTIONS

A. Drug-Drug Interactions:

Before taking FEBULIFE 40 TABLET, inform your doctor if you are taking any of the following medicine:

  • mercaptopurine (used to treat cancer)
  • azathioprine (used to reduce immune response)
  • theophylline (used to treat asthma)

Overdosage:

If you or anyone else accidentally takes too much of FEBULIFE 40 TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

Drug :  

Febuxostat

Pharmacological Category :  

Xanthine oxidase inhibitors

Therapeutic Indication :  

Gout, blood cancer patients undergoing chemotherapy

Dosage Forms :  

Tablet

MORE INFORMATION

  • Keep the medicine out of reach from children
  • Store FEBULIFE 40 TABLET at room temperature

FAQs ABOUT FEBULIFE 40 TABLET

What is FEBULIFE 40 TABLET used for?

FEBULIFE 40 TABLET is used in adults to treat gout (form of arthritis that occur when too much uric acid crystallises and deposits in the joints) and used to prevent high blood levels of uric acid in blood cancer patients receiving chemotherapy.

What are the side effects of FEBULIFE 40 TABLET?

FEBULIFE 40 TABLET can commonly cause side effects such as abnormal liver function test results, diarrhea, headache, skin rash, nausea, exaggerated gout symptoms and oedema. If you feel any of these getting worse, please consult your doctor immediately.

Does FEBULIFE 40 TABLET reduce uric acid levels?

Yes, FEBULIFE 40 TABLET works by blocking the action of an enzyme called xanthine oxidase, which is involved in the process of converting hypoxanthine into uric acid (purine metabolism pathway). This type of action reduces high uric acid levels in gout and blood cancer patients undergoing chemotherapy treatment.

What happens if I stop taking FEBULIFE 40 TABLET?

Once you are prescribed FEBULIFE 40 TABLET it is very important that you do not stop taking it unless advised by your doctor or unless side effects develop. If FEBULIFE 40 TABLET treatment is stopped, there is a high risk that your gout may worsen. You should continue to take it even if you do not have symptoms.

Is FEBULIFE 40 TABLET good for kidney?

No, FEBULIFE 40 TABLET might affect the function of the kidney, resulting in kidney stones, changes in the amount of urine, abnormally frequent urination, and an increased level of proteins in the urine). If you experience any of these symptoms while taking FEBULIFE 40 TABLET, please consult your doctor immediately.

REFERENCES

1. KD Tripathi. Section 11, Antirheumatoid and Antigout Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 210-218.

2. N. Lawrence Edwards, Febuxostat: a new treatment for hyperuricemia in gout, Rheumatology. [Revised in May 2009] [Accessed on 18th July 2022] https://doi.org/10.1093/rheumatology/kep088

3. Schumacher Jr, H. R., M. A. Becker, E. Lloyd, P. A. MacDonald, and C. Lademacher. Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study. Rheumatology. [Revised in June 2009] [Accessed on 18th July 2022] https://doi.org/10.1093/eurheartj/ehz119

4. MIAS Pharma Limited. Electronic Medicines Compendium (EMC). [Revised in June 2021] [Accessed on 18th July 2022] https://www.medicines.org.uk/emc/files/pil.11500.pdf

5. Takeda Pharmaceuticals Inc. U.S. Food & Drug Administration. [Revised in March 2013] [Accessed on 18th July 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021856s011lbl.pdf

PRODUCT DETAILS

    Country Of Origin
    India
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

FEBULIFE 40 Tablet 10's

FEBULIFE 40 Tablet 10's Mkt: Renauxe Pharma India Pvt Ltd

M.R.P.: Rs.99.50
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