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INTRODUCTION
F TIN 40 TABLET contains Fluoxetine which belongs to the group of medicines called Anti-depressants. It is used to treat major depressive episodes, obsessive-compulsive disorder (mental disorder) and bulimia nervosa (eating disorder).
Major depressive disorder is a mental health disorder characterized by a persistent and intense feeling of sadness for an extended duration of time. It mainly impacts mood, behavior and other physical functions, such as sleep and appetite.
Obsessive-compulsive disorder (OCD) is a mental disorder that is associated with repetitive thoughts (obsessions) and the urge to do things over and again (compulsions).
Bulimia nervosa is a serious eating disorder that is characterized by binge eating followed by methods to avoid being overweight such as vomiting, severe exercise or fasting.
Before taking F TIN 40 TABLET, inform your doctor if you have or ever had epilepsy or fits, history of mania, diabetes, liver problems, heart problems and glaucoma.
F TIN 40 TABLET is not recommended for use in pregnancy and breastfeeding women as it may harm the unborn baby. Consult your doctor for advice.
The most common side effects of taking F TIN 40 TABLET are insomnia, headache, diarrhea, feeling sick (nausea) and fatigue. Contact your physician if any of the above side effects worsen.
USES OF F TIN 40 TABLET
Treats:
- major depressive episodes
- obsessive-compulsive disorder (mental disorder)
- bulimia nervosa (eating disorder)
HOW F TIN 40 TABLET WORKS
F TIN 40 TABLET works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and relieves symptoms of panic and obsessive disorders.
DIRECTIONS FOR USE
Take F TIN 40 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking F TIN 40 TABLET without consulting your doctor.
SIDE EFFECTS OF F TIN 40 TABLET
COMMON
- insomnia
- headache
- diarrhea
- nausea
- fatigue
- not feeling hungry, weight loss
- nervousness, anxiety
- poor concentration
- sleepiness, unusual dreams, tiredness
- dizziness
- change in taste
- uncontrollable shaking movements
- blurred vision
- rapid and irregular heartbeat sensation
- flushing
- yawning
- indigestion, vomiting
- dry mouth
- rash, urticaria, itching
- excessive sweating
- joint pain
- passing urine more frequently
- unexplained vaginal bleeding
- feeling shaky or chills
UNCOMMON
- feeling detached from yourself
- strange thinking
- abnormally high mood
- orgasm problems
- teeth grinding
- muscle twitching, problems with balance or coordination
- memory impairment
- enlarged (dilated) pupils
- ringing in the ears
- low blood pressure
- shortness of breath
- nose bleeds
- difficulty swallowing
- hair loss
- increased tendency to bruising or bleeding
- difficulty passing urine
- feeling hot or cold
- abnormal liver function test results
- feeling general discomfort or illness
- memory problems
RARE
- low salt levels in the blood
- reduced platelets in the blood, decrease in white blood cells
- untypical wild behaviour
- hallucinations
- agitation
- panic attacks
- confusion
- stuttering
- aggression
- fits
- vasculitis (inflammation of a blood vessel)
- rapid swelling of the tissues around the neck, mouth, face or throat
- pain in the tube that takes food or water to the stomach
- hepatitis (inflammation of the liver)
- lung problems
- sensitivity to sunlight
- muscle pain
- producing breast milk
Stop taking F TIN 40 TABLET and contact your doctor immediately if you experience any of the following side effects:
- self-harming thoughts
- rash or allergic reaction such as itching, swelling of face, neck, lips, tongue, mouth or throat or wheezing/shortness of breath
- restlessness and cannot sit or stand still, may have akathisia
- a combination of symptoms (serotonin syndrome) including unexplained fever with faster breathing or heart rate, sweating, muscle stiffness or tremor, confusion, extreme agitation or sleepiness
- drowsiness, weakness or confusion (mostly in elderly people)
- prolonged and painful erection
- irritability and extreme agitation
- fast or irregular heart rate, collapsing, fainting or dizziness upon standing which may indicate abnormal functioning of the heart rate
- widespread rash, circular, irregular red patches on the hands and arms (Erythema Multiforme), severe skin rash with fever, redness, blisters or ulcers (Stevens-Johnson Syndrome), severe rash involving reddening, peeling and swelling of the skin resembling severe burns (Toxic Epidermal Necrolysis)
- bleeding from stomach or intestines Ex. black tarry stools, unexplained bruise or bleeding and fever, sore throat, tiredness due to decreased blood cells
- yellowing of the skin or eyes (jaundice) or tiredness, pain in abdomen, joints or muscles
HOW TO MANAGE SIDE EFFECTS
Nausea or Vomiting:
Take this medicine with or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. Contact your doctor if nausea and vomiting do not improve.
Diarrhea:
Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for treating diarrhea. Contact your doctor if your if it persists for a long time.
Headache:
Rest and relax. Drink plenty of fluids such as water and electrolytes. Apply a pain-relieving balm on the head if necessary. Do not consume alcohol. Contact your doctor if your headache did not improve.
Dizziness or Drowsiness:
Try to rest and relax. Get enough sleep. Avoid driving or operate any machines while you are feeling dizzy. Do not drink alcohol, as it can aggravate your dizziness. Contact your doctor if your dizziness or drowsiness did not improve.
WARNING & PRECAUTIONS
PREGNANCY
F TIN 40 TABLET is not recommended for use especially in the last 3 months of pregnancy as it harms the unborn baby. It should be used with caution during late pregnancy or just before giving birth. Consult your doctor before taking F TIN 40 TABLET.
BREASTFEEDING
F TIN 40 TABLET will be excreted through breast milk., hence it should be used with caution if it is clearly necessary. Your doctor will lower the dose accordingly. Consult your doctor before taking F TIN 40 TABLET.
DRIVING AND USING MACHINES
Do not drive or operate any machines as it may affect your judgement or coordination after taking F TIN 40 TABLET.
ALCOHOL
Avoid consumption of alcohol while taking F TIN 40 TABLET. Consult your doctor before taking.
KIDNEY
F TIN 40 TABLET should be used with caution in patients with kidney problems. Consult your doctor before taking F TIN 40 TABLET.
LIVER
F TIN 40 TABLET should be used with caution in patients with liver problems. Consult your doctor before taking F TIN 40 TABLET.
ALLERGY
Do not take F TIN 40 TABLET if you are allergic to Fluoxetine or to any other ingredients of this medicine.
LUNGS
F TIN 40 TABLET should be used with caution in patients with lung problems. Consult your doctor before taking F TIN 40 TABLET.
HEART DISEASE
F TIN 40 TABLET should be used with caution in patients with heart problems or low heart rate. Consult your doctor before taking F TIN 40 TABLET.
OTHERS
Before taking F TIN 40 TABLET, inform your doctor if you:
- have or ever had epilepsy or fits
- have history of mania
- have diabetes
- have glaucoma
- have ongoing ECT (electroconvulsive therapy)
- have a history of bleeding disorder
Use in pediatrics:
Your doctor will give the right dose depends on your child’s age, body weight and disease condition. Consult your doctor for advice before taking.
Use in geriatrics:
F TIN 40 TABLET should be used with caution in elderly patients (above 70 years of age). Consult your doctor before taking F TIN 40 TABLET.
INTERACTIONS
A. Drug-Drug interactions:
Before taking F TIN 40 TABLET, inform your doctor if you are taking any of the following medicine:
- medicine used to treat depression (Ex. tranylcypromine, moclobemide iproniazid, nialamide, isocarboxazid, toloxatone)
- linezolid (used for bacterial infections)
- methylthioninium chloride (used to treat methaemoglobinaemia)
- selegiline (used for parkinson's disease)
- lithium (used to mania)
- L- tryptophan (used to treat premenstrual disorders)
- medicines used to treat epilepsy (Ex. phenytoin, carbamazepine, oxcarbazepine)
- medicine used as a pain killer (Ex. tramadol)
- medicine used to treat migraine (Ex. sumatriptan)
- medicine used to treat heart’s rhythm (Ex. Class IA and III antiarrhythmics like quinidine and amiodarone)
- medicine used as antipsychotics (Ex. phenothiazine derivatives like fluphenazine, pimozide, haloperidol)
- medicine used as antimicrobial agents (Ex. sparfloxacin, moxifloxacin, erythromycin IV, pentamidine)
- medicine used to treat malaria (Ex. halofantrine, mefloquine, chloroquine)
- medicines used to treat allergies (astemizole, mizolastine, mequitazine, cyproheptadine)
- medicine used for heart problems (Ex. flecainide or encainide)
- nebivolol (medicines used for high blood pressure)
- atomoxetine (medicines used to treat attention deficit hyperactivity disorder)
- chlorothiazide (used to remove sodium and water from the body)
- desmopressin (used to reduce the amount of urine produced by the kidneys)
- medicine used for depression (Ex. imipramine, desipramine, amitriptyline and selective serotonin reuptake inhibitors Ex. citalopram, escitalopram) and or St John’s wort (herbal medicine)
- medicine used to treat breast cancer (Ex. tamoxifen)
- medicine used to thin the blood (Ex. warfarin, aspirin)
- ibuprofen, diclofenac, tramadol (medicines used to treat pain)
- medicines used to treat certain mental disorders (Ex. clozapine)
- metoprolol (medicines used for heart failure)
- buprenorphine/naloxone (medicines used for opioid dependence)
- bupropion (medicines helps to stop smoking)
Overdosage:
If you or anyone else accidentally took too much of F TIN 40 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are nausea, vomiting, seizures, heart problems (ranging from irregular heartbeat with no symptoms, heart attack (cardiac arrest), lungs not working properly (pulmonary dysfunction), central nervous system (CNS) alterations (excitation and an altered level of consciousness or loss of consciousness) or coma.
SYNOPSIS
| Drug | : | Fluoxetine |
| Pharmacological Category | : | Anti-depressants |
| Therapeutic Indication | : | Major depressive episodes, Obsessive-compulsive disorder, Bulimia nervosa |
| Dosage Forms | : | Tablet, Capsule, Suspension |
MORE INFORMATION
- Keep F TIN 40 TABLET out of reach of children
- Store at a temperature below 25°C
FAQs ABOUT F TIN 40 TABLET
For what conditions F TIN 40 TABLET is used?
F TIN 40 TABLET is used to treat major depressive episodes, obsessive-compulsive disorder (mental disorder) and bulimia nervosa (eating disorder). Contact your before taking F TIN 40 TABLET.
Is it safe to use F TIN 40 TABLET if I have glaucoma?
Yes. F TIN 40 TABLET may cause increased pressure in the eye in patients having glaucoma. Consult your doctor before taking F TIN 40 TABLET.
Is it safe to use F TIN 40 TABLET in elder people?
Yes. F TIN 40 TABLET should be used with caution in elderly patients (above 70 years of age). Consult your doctor before taking F TIN 40 TABLET.
Can I take F TIN 40 TABLET if I have diabetes?
Yes. F TIN 40 TABLET should be taken with caution in patients with diabetes as it might fluctuate blood glucose levels. Monitor blood sugar levels frequently. Consult your doctor before taking F TIN 40 TABLET.
What are the common side effects of F TIN 40 TABLET?
The most common side effects of taking F TIN 40 TABLET are insomnia, headache, diarrhea, feeling sick (nausea) and fatigue. Contact your physician if any of the above side effects worsen.
REFERENCES
1. James M. O’Donnell, Robert R. Bies, and Richard C. Shelton. Drug Therapy of Depression and Anxiety Disorders, Goodman & Gilman’s: The Pharmacological basics of Therapeutic, 13th Edition. New York McGraw Hill Medical 2018. Page – 267-277.
2. Andrea Rossi, Alessandra Barraco, and Pietro Donda. Fluoxetine: a review on evidence-based medicine. Journal of Annals of General Hospital Psychiatry. February 2004 [Accessed on 13th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC356924/
3. S Alboni, R M van Dijk, S Poggini, G Milior, M Perrotta, T Drenth, N Brunello, D P Wolfer, C Limatola, I Amrein, F Cirulli, L Maggi & I Branchi. Uses of Fluoxetine. Journal of Molecular Psychiatry. November 2015 [Accessed on 13th June 2022] https://www.nature.com/articles/mp2015142
4. Carla Carratala-Ros, Laura Lopez-Cruz, Andrea Martinez-Verdu, Regulo Olivares-Garcia, John D. Salamone and Merce Correa. Impact of Fluoxetine on behaviour. Frontiers in Behavioural Neuroscience. July 2021 [Accessed on 13th June 2022] https://www.frontiersin.org/articles/10.3389/fnbeh.2021.700182/full
5. Accord limited. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 13th June 2022] https://www.medicines.org.uk/emc/files/pil.5787.pdf
6. Endo Ventures Ltd. Electronic Medicines Compendium (EMC). [Revised in January 2021] [Accessed on 13th June 2022] https://www.medicines.org.uk/emc/files/pil.9338.pdf
AUTHOR DETAILS
Written By Dr. Janet.C, Pharm.D
Last updated on 28 Sep 2022 | 04:39 PM(IST)
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