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Drug Information

What is Repaglinide used for?

Repaglinide is used for the treatment of type 2 diabetes. This drug should be used in conjunction with proper diet and regular exercise for effective glycaemic control.

Repaglinide may also be prescribed for other conditions as determined by the doctor.

How does Repaglinide work?

Repaglinide belongs to the class of drugs called oral hypoglycaemic agents. This drug acts by stimulating the insulin release from the pancreas. This action is produced by opening the calcium channels in the intracellular spaces, which enhances the release of insulin. This drug helps in lowering the glucose levels during the meals, but a long-term treatment is required for effective glycaemic control.

How to take Repaglinide?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Repaglinide as prescribed by your doctor.

Swallow the tablet whole. Do not crush or chew the tablet. Take the drug at least 30 minutes before a meal.

If you miss a dose of Repaglinide, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

The overdose symptoms of Repaglinide may include:

  • Blood vomiting
  • Dizziness
  • Increased sweating
  • Seizures
  • Sweating

You must seek immediate medical care if you experience any of the above symptoms.

What are the drugs that interact with Repaglinide?

Drugs that interact with Repaglinide include the following:

  • Carbamazepine
  • Clopidogrel
  • Cyclosporine
  • Gatifloxacin
  • Gemfibrozil
  • Itraconazole
  • Rifampicin

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Repaglinide?

The following are the most common side effects of Repaglinide:

  • Abdominal discomfort
  • Anxiety
  • Chills
  • Cold sweat
  • Confusion
  • Increased urination
  • Increased hunger
  • Increased thirst
  • Shivering

The following are the severe side effects and you may require immediate medical attention:

  • Blurry vision
  • Coma
  • Increased heart rate
  • Joint pains
  • Rhinitis
  • Seizures
  • Severe diarrhoea

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Repaglinide?

  • Avoid taking the medicine if you are allergic to Repaglinide or similar drugs.
  • Be cautious while taking Repaglinide if you have any kidney or liver impairment.
  • Avoid consumption of alcohol as it may alter the absorption of Repaglinide.
  • Do not stop using the medication abruptly unless instructed by the doctor. Stopping the medication suddenly may alter the blood sugar levels.
  • Do not exceed the dose more than what is prescribed.

You are advised not to take Repaglinide if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Repaglinide?

  • Tell your doctor if you have any history of hypertension, liver and kidney disorders.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • If you have to undergo any surgery or medical procedure, you must inform the doctor about the usage of Repaglinide.
  • Inform the doctor if you have any history of allergic reaction with the usage of Repaglinide.
  • Notify the doctor if you are pregnant or breastfeeding.

Frequently asked questions about Repaglinide

  1. How long can I take Repaglinide?
  2. Repaglinide tablet is recommended for a long-term treatment. A change in the drug may be recommended if the medicine is not effective in later treatment stages. Please consult your doctor.

  3. Should I follow any special dietary instructions while taking Repaglinide?
  4. Yes, proper diabetic diet accompanied with regular exercise is advised while on Repaglinide medication.

  5. Do I need to be monitored for any laboratory parameters while taking Repaglinide?
  6. Yes, regular monitoring of blood sugar levels is recommended while using Repaglinide tablet.

  7. Can I use Repaglinide to treat type 1 diabetes?
  8. No, Repaglinide is only used to treat type 2 diabetes. Please consult your doctor for an appropriate medication to treat type 1 diabetes.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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