Best Price*  ₹ 40.80
MRP ₹51.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mfr: Intas Pharmaceuticals Ltd * Country of Origin: India

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What is ESPIN?

  • ESPIN contains Amlodipine Besylate and Hydrochlorothiazide
  • Amlodipine Besylate belongs to a group of medicines called calcium antagonists
  • Hydrochlorothiazide belongs to a group of medicines called thiazide diuretics
Therapeutic Uses
Warning & Precautions
Directions & For Use
Side Effects
More Information

What ESPIN is used for?

  • It is used to treat high blood pressure (hypertension)

Talk to Doctor

Pregnancy & Breast Feeding

Children & Adolescents

Driving & Using Machines

Talk to your doctor before taking this medicine, if you:

  • are allergic to amlodipine besylate or hydrochlorothiazide or any other ingredients of this medicine
  • are suffering from cardiogenic shock
  • are suffering from narrowing of the aortic heart valve (aortic stenosis) or suffer from heart failure after a heart attack
  • suffer from chest pain at rest or with minimal effort (unstable angina pectoris)
  • have severe low blood pressure (hypotension)
  • have liver, kidney problems
  • have anuria (significantly decreased urine output)
  • have bronchial asthma
  • have systemic lupus erythematosus
  • suffer from acute myopia and secondary angle-closure glaucoma
  • have seizures
  • have tachycardia
  • have hypokalemia, hyponatremia
  • have hyperuricemia, hyperglycemia
  • have acute gout
  • have hyperparathyroidism
  • If you are pregnant or breast-feeding, think you may be pregnant or planning to have a baby, ask your doctor for advice before using this medicine
  • Consult your doctor before taking this medicine
  • If you feel sick, dizzy or tired, or give you a headache when taking this medicine, do not drive or use any tools or machines

Tell your doctor if you are taking,

  • dihydropyridine derivates like felodipine, nifedipine, nimodipine)
  • medicines that can lower blood pressure (e.g. verapamil, diltiazem)
  • ketoconazole and itraconazole (antifungal medicines used to treat skin and fungal infections)
  • protease-inhibitors (antiviral medicines used to treat HIV infections, e.g. ritonavir, indinavir, nelfinavir, nevirapine)
  • clarithromycin, erythromycin and telithromycin, rifampicin, rifabutin (antibiotics)
  • nefazodone (medicine to treat depression)
  • dexamethasone (corticosteroid used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis)
  • dantrolene (infusion for severe body temperature abnormalities)
  • tacrolimus (medicine used to alter the way your immune system works)
  • simvastatin (cholesterol lowering medicine)
  • cyclosporine (an immunosuppressant)
  • phenobarbital, phenytoin and carbamazepine (medicines for epilepsy)
  • sildenafil (medicine for impotence)
  • medicines used to treat pain ex: narcotics
  • antidiabetic drugs (oral agents and insulin)
  • antihypertensive drugs
  • cholestyramine and colestipol resins
  • corticosteroids
  • pressor amines (e.g. norepinephrine)
  • skeletal muscle relaxants, nondepolarizing (e.g. tubocurarine)
  • medicine used to treat some types of psychiatric diseases (e.g. lithium)
  • medicine used to treat pain ex: non-steroidal anti-inflammatory drugs
  • Always take this medicine exactly as your doctor has told you
  • Take this medicine by mouth at the same time of the day each day
  • This medicine can be swallowed with a whole glass of water
  • Do not crush or chew the tablets
  • Do not take this medicine with grapefruit juice

If you take more ESPIN

  • If you take too many ESPIN or if someone else has taken your medicine, talk to your doctor immediately and you may need medical attention
  • Symptoms of an overdose are: extreme dizziness and/or feeling very light-headed, faint or weak, problems with breathing, having to urinate very often, shock, skin could feel cool and clammy and you could lose consciousness, dehydration

 If you forget to take ESPIN

  • If you have forgotten to take your ESPIN take them as soon as possible on the same day. Do not take a double dose

If you stop taking ESPIN

  • Do not stop taking ESPIN without talking to your doctor first
Very Rare

Like all medicines this medicine can cause side effects although not everybody gets them.

  • sudden wheeziness, chest pain, shortness of breath or difficulty in breathing
  • swelling of eyelids, face or lips
  • swelling of the tongue and throat which causes great difficulty breathing
  • severe skin reactions including intense skin rash, hives, reddening of the skin over your whole body, severe itching, blistering, peeling and swelling of the skin, inflammation of mucous membranes (Stevens Johnson syndrome) toxic epidermal necrolysis
  • heart attack, abnormal heart beat
  • inflamed pancreas which may cause severe abdominal and back pain accompanied with feeling very unwell
  • headache, dizziness, sleepiness (especially at the beginning of treatment)
  • palpitations (awareness of your heart beat), flushing
  • abdominal pain, feeling sick(nausea)
  • altered bowel habits, diarrhoea, constipation, indigestion,
  • tiredness, weakness
  • visual disturbances, double vision
  • muscle cramps
  • enlarged breasts or discomfort in men
  • sleep disorders, irritability, depression
  • pain, feeling unwell, dry mouth, uncontrolled shaking, pins and needles, increased sweating
  • problems with your eye-sight (visual disturbances)
  • mood changes, anxiety, depression, sleeplessness
  • trembling, taste abnormalities
  • numbness or tingling sensation in your limbs, loss of pain sensation
  • sneezing/running nose caused by inflammation of the lining of the nose (rhinitis)
  • disorder in passing urine, increased need to urinate at night, increased number of times of passing urine
  • ringing or buzzing in the ears
  • fainting, increased heart rate, chest pain, aggravation of angina may occur at the beginning of the treatment
  • inflammation of the blood vessels
  • breathing difficulties, inflammation of the nasal mucosa, cough
  • dry mouth, vomiting (being sick), diarrhoea, constipation, swollen gums
  • prickling and tingling sensation of the skin, itching, red patches on skin, nettle rash, hair loss, discoloration of the skin
  • muscle cramps, back pain, muscle and joint pain
  • increased need to urinate
  • impotence
  • increase or decrease in weight
  • Confusion
  • decreased numbers of white blood cells, decrease in blood platelets which may result in

unusual bruising or easy bleeding (red blood cell damage)

  • excess sugar in blood (hyperglycaemia)
  • a disorder of the nerves which can cause weakness, tingling or numbness
  • swelling of the gums
  • abdominal bloating (gastritis)
  • abnormal liver function, inflammation of the liver (hepatitis), yellowing of the skin (jaundice), liver enzyme increases which may influence some medical tests
  • increased muscle tension
  • inflammation of blood vessels, often with skin rash
  • sensitivity to light
  • disorders combining rigidity, tremor, and/or movement disorders
Additional Information


  • Protect from excess heat and light
  • Keep out of reach of children
  • Store at room temperature (15-25ºC)
  • Do not use this medicine after the expiry date

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Espin H Tablet 10'S

Espin H Tablet 10'S Mfr: Intas Pharmaceuticals Ltd

M.R.P.: Rs.51.00
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