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ESOBRINT 40 TABLET contains Esomeprazole which belongs to the group of medicines called Proton pump inhibitors. It is used for the treatment of Gastroesophageal reflux disease (GERD) heartburn in adults and in adolescents above 12 years of age. ESOBRINT 40 TABLET also helps in treating stomach ulcers or upper part of the gut (intestine) that are infected with Helicobacter pylori bacteria and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) medicines in adults and in adolescents above 12 years of age. It is also used to treat Zollinger-Ellison syndrome (too much acid produced in the stomach caused by a growth in the pancreas).
GERD is a disease where acid from the stomach escapes into the tube which connects your throat to your stomach (oesophagus) causing pain and inflammation.
ESOBRINT 40 TABLET is not recommended to be taken in patients with severe kidney and liver failure. ESOBRINT 40 TABLET should be taken only if considered clearly necessary by your doctor in pregnant women. It is not recommended for use in breast-feeding women. Consult your doctor for advice before taking the medicine.
ESOBRINT 40 TABLET is not recommended for children and adolescents aged less than 12 years. Consult your doctor for advice before taking the medicine.
The most common side effects of taking ESOBRINT 40 TABLET are headache, diarrhoea, stomach pain, constipation, flatulence, nausea and vomiting. Contact your physician if any of the above symptoms worsens with time.
Used to treat:
ESOBRINT 40 TABLET is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of enzymes in the stomach cell. It hence reduces gastric acidity by blocking the final step in acid production and helps in relief of acid related indigestion and heartburn.
Take ESOBRINT 40 TABLET as advised by your doctor. It can be taken with or without food. Swallow ESOBRINT 40 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking ESOBRINT 40 TABLET and consult your doctor immediately if you experience any of the following side effects:
Rest and relax. Frequently hydrate yourself by drinking plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if needed. Do not consume too much of alcohol. Consult your doctor if symptom worsens.
Drink plenty of liquids such as water, fruit juices or electrolytes to avoid loss of water (dehydration) in your body. Consult your doctor if the symptom persists for long time.
Nausea and Vomiting:
Try to take ESOBRINT 40 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food.
ESOBRINT 40 TABLET should be used during pregnancy only if considered clearly necessary. Consult your doctor before taking ESOBRINT 40 TABLET.
ESOBRINT 40 TABLET is not recommended for use in breast feeding women as it is unclear whether it passes through the breast milk. Consult your doctor before taking ESOBRINT 40 TABLET.
Do not drive or operate any heavy tools or machines if you experience dizziness and blurred vision after taking ESOBRINT 40 TABLET. Consult your doctor before taking ESOBRINT 40 TABLET.
Avoid or limit the consumption of alcohol while taking ESOBRINT 40 TABLET because it might increase the amount of acid in your stomach than normal which can irritate your stomach lining and worsen your symptoms.
ESOBRINT 40 TABLET should be used with caution in patients with severe kidney problems. Consult your doctor before taking ESOBRINT 40 TABLET.
[GBNKWEYWORD] should be used with caution in patients with severe liver problems. Consult your doctor before taking ESOBRINT 40 TABLET.
Do not take ESOBRINT 40 TABLET if you are allergic to Esomeprazole or to any other proton pump inhibitor medicines.
Before taking ESOBRINT 40 TABLET, inform your doctor if you:
Use in pediatrics:
ESOBRINT 40 TABLET is not recommended to be taken in children and adolescents below 12 years of age. Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before taking ESOBRINT 40 TABLET.
Use in geriatrics:
ESOBRINT 40 TABLET should be taken with caution in elderly patients (65 years and above). Consult your doctor before taking ESOBRINT 40 TABLET.
A. Drug-Drug interactions:
Before taking ESOBRINT 40 TABLET inform your doctor if you are taking any of these medicines:
If you or anyone else accidentally take more of ESOBRINT 40 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose may include reduced physical (motor) activity, changes in respiratory rate, tremor, coordination-balance-speech disorders (ataxia) and intermittent fits (clonic convulsions).
|Pharmacological Category||:||Proton Pump Inhibitors|
|Therapeutic Indication||:||Gastroesophageal reflux disease (GERD), Stomach ulcers, Intestinal ulcers caused by NSAID’s, Prevents rebleeding following therapeutic endoscopic procedures done for acute bleeding stomach (gastric) or intestinal (duodenal) ulcers|
|Dosage Forms||:||Tablet, Capsule, Injection, Infusion, Sachet, Granules|
Can ESOBRINT 40 TABLET used to treat heartburn?
Yes. ESOBRINT 40 TABLET contains Esomeprazole used to treat symptoms of stomach acid reflux such as heartburn and indigestion. Consult your doctor regarding the symptoms before taking it.
Can I take an antacid along with ESOBRINT 40 TABLET?
Yes. It is safe to take ESOBRINT 40 TABLET with antacids as there is no known interaction. However, consult your doctor before taking it together.
Is ESOBRINT 40 TABLET addictive in nature?
No, ESOBRINT 40 TABLET is not addictive in nature and you can continue ESOBRINT 40 TABLET to take as long as it is of benefit to you. Consult your doctor to assess your treatment on a regular basis.
How and when ESOBRINT 40 TABLET should be taken?
Take ESOBRINT 40 TABLET as advised by your doctor and can be taken with or without food. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Can ESOBRINT 40 TABLET be taken in pregnant women?
ESOBRINT 40 TABLET should be taken in pregnant women only if considered clearly necessary by your doctor. If you think you may be pregnant or planning to become pregnant, consult your doctor for advice before taking ESOBRINT 40 TABLET.
Can ESOBRINT 40 TABLET cause headache?
Yes, headache is one of the most common side effects of taking ESOBRINT 40 TABLET. In case if you are experiencing a headache after taking ESOBRINT 40 TABLET, try to rest and relax. Keep drinking plenty of fluids such as water. Apply a pain-relieving balm on the forehead if needed. Consult your doctor if headache persists for a long time.
1. KD Tripathi. Drugs for Peptic Ulcer and G.E.R.D. Essentials of Medical Pharmacology. seventh edition. 2013. Page – 649, 653, 657.
2. Franke, Andreas, Caroline Hepp, Hermann Harder, Christoph Beglinger, and Manfred V. Singer. Esomeprazole reduces gastroesophageal reflux after beer consumption in healthy volunteers. Scandinavian journal of gastroenterology. NIH National Library of Medicines, National Library of Medicine. 2008. [Accessed on 11th June 2022] https://pubmed.ncbi.nlm.nih.gov/18924018/
3. Sun Pharmaceutical Industries Europe B.V. Electronic Medicines Compendium (EMC). [Revised in March 2021] [Accessed on 11th June 2022] https://www.medicines.org.uk/emc/files/pil.2326.pdf
4. Astra Zeneca Pharmaceuticals LP. U.S. Food & Drug Administration. [Revised in December 2014] [Accessed on 11th June 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022101s014021957s017021153s050lbl.pdf
5. AstraZeneca Pharmaceuticals (Ptd) Limited. [Revised in October 2020] [Accessed on 11th June 2022] https://www.sahpra.org.za/wp-content/uploads/2020/08/Nexium-Sachets_PIL_AstraZeneca_MCC-Format-02-October-2020.pdf
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