ERYPRO PREFIL 2000IU (PFS) contains Erythropoietin alfa which belongs to a group of medicines called Erythropoiesis-Stimulating agent (ESA). It is used to treat symptomatic anaemia caused by kidney disease (in children on haemodialysis, in adults on haemodialysis or peritoneal dialysis and in severely anaemic adults not yet undergoing dialysis), anaemia in adults receiving chemotherapy for solid tumors. It is also used to treat moderately anaemic adults who donate their blood before surgery, in patients about to have major orthopaedic surgery and anaemia in patients with a bone marrow disorder that causes a severe disruption in the creation of blood cells (myelodysplastic syndromes).
Erythropoietin alfa (epoetin alfa) is a protein that stimulates the bone marrow to produce more red blood cells which carry haemoglobin (a substance that transports oxygen).
This medicine will be administered by your doctor or nurse by intravenous or subcutaneous route. Before receiving ERYPRO PREFIL 2000IU (PFS), tell your physician if you have high blood pressure, blood clotting diseases or problems related to liver, kidney and heart. Pregnant and breastfeeding women are recommended to consult the doctor before receiving this medicine. The common side effects are diarrhea, vomiting, headache, redness, burning and pain at the site of injection.
Treats,
ERYPRO PREFIL 2000IU (PFS) belongs to erythropoiesis-stimulating agents which works by causing the bone marrow (soft tissue inside the bones where blood is made) to make more red blood cells.
ERYPRO PREFIL 2000IU (PFS) will be administered intravenously or subcutaneously (under the skin) by your doctor or nurse.
Headache:
Rest and drink plenty of fluids. Apply a wet or cold cloth on forehead and rest in a quiet, comfortable and dark room.
Diarrhoea:
Drink plenty of fluids to avoid dehydration. ORS can also be used to prevent dehydration.
Vomiting:
Drink clear or ice-cold drinks. Eat light and bland foods. Avoid sweets.
Pregnant women, consult your doctor before using ERYPRO PREFIL 2000IU (PFS).
It is not known whether ERYPRO PREFIL 2000IU (PFS) is excreted in human milk. Consult your doctor for advice.
ERYPRO PREFIL 2000IU (PFS) should be used with caution in patients with kidney disease. Consult your doctor for advice.
ERYPRO PREFIL 2000IU (PFS) should be used with caution in patients with liver disease. Consult your doctor for advice.
Tell your doctor if you are allergic (hypersensitive) to Erythropoietin alfa.
ERYPRO PREFIL 2000IU (PFS) should be used with caution in patients with lung disease. Consult your doctor for advice.
ERYPRO PREFIL 2000IU (PFS) is not recommended in patients with recent episodes of heart attack or stroke, severe heart disease, severe disorders of the veins and arteries. Consult your doctor for advice.
Tell your doctor before taking this medicine if you,
Use in pediatrics:
Use in geriatrics:
A. Drug - Drug interactions:
Tell the doctor about all the medications including prescription, non-prescription and herbal supplements.
Overdosage:
Drug | : | Erythropoietin alfa (epoetin alfa) |
Pharmacological Category | : | Erythropoiesis-Stimulating Agent (ESA) |
Therapeutic Indication | : | Anemia due to chemotherapy in patients with cancer, chronic kidney disease |
Dosage Forms | : | Injection |
What is ERYPRO PREFIL 2000IU (PFS) used for?
ERYPRO PREFIL 2000IU (PFS) helps your body make more red blood cells.
How do I know if ERYPRO PREFIL 2000IU (PFS) is working?
Your doctor will test the blood regularly, at least weekly at the beginning of your treatment.
What should I check before taking ERYPRO PREFIL 2000IU (PFS)?
You will be monitored regularly by your doctor while you are taking this medicine.
Can ERYPRO PREFIL 2000IU (PFS) affect blood pressure?
Yes. During initial therapy, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure.
1. KD Tripathi MD. Haematinics and Erythropoietin. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 611.
2. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page -1071-1072.
3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 479-481.
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5. Janssen Products, LP. Amgen Inc. [Revised on May, 2012] [Accessed on Sep 25, 2021] https://www.janssenlabels.com/package-insert/product-monograph/prescribing-information/PROCRIT-pi.pdf
6. Ortho Biotech Products, L.P. Amgen Inc. U.S. Food & Drug Administration; [Revised on Aug, 2008] [Accessed on Sep 25, 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/103234s5196pi.pdf
7. Drugs.com. Epoetin Alfa. [Revised on June 02, 2020] [Accessed on Sep 25, 2021] https://www.drugs.com/ppa/epoetin-alfa.html
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